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MRP: Rs. 882.86 for 1 vial(s) (1 ML injection each)
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Composition for IFOXAN + MESNA

Mesna(2 gm),Ifosfamide(NA)

food interaction for IFOXAN + MESNA

alcohol interaction for IFOXAN + MESNA

pregnancy interaction for IFOXAN + MESNA

lactation interaction for IFOXAN + MESNA

There is no data available. Please consult doctor before consuming the drug.
Ifoxan + mesna injection may cause excessive drowsiness and calmness with alcohol.
Ifoxan + mesna injection is unsafe to use during pregnancy.
There is positive evidence of human fetal risk, but the benefits from use in pregnant women may be acceptable despite the risk, for example in life-threatening situations. Please consult your doctor.
Ifoxan + mesna injection is probably unsafe to use during breastfeeding. Please consult your doctor.


Mesna(2 gm)


Mesna is used to prevent and reduce the bleeding in the urinary bladder (haemorrhagic cystitis) in the patients who receive ifosfamide or higher doses of cyclophosphamide given during the cancer treatment (chemotherapy).

How it works

Mesna belongs toabdominal pain a class of drugs called cytoprotectants. It protects the urinary bladder from harmful effects of ifosfamide and cyclophosphamide.

Common side effects

Vomiting, Nausea, Drowsiness, Abdominal pain, Application site redness of skin, Application site irritation, Constipation, Cough, Diarrhoea, Fever, Fatigue, Dizziness, Flushing, Hair loss, Headache, Weight loss, Loss of appetite, Loss of strength, Muscle pain, Joint pain, Sore throat


Ifosfamide is used in combination with other anticancer drugs to treat cancer of the bronchi, breast, testes (male gonads), bladder, head, neck, bone (osteogenic sarcoma), and blood (lymphoma).

How it works

Ifosfamide belongs to group of medicines called alkylating agents. It inhibits the growth of cancer cells (cytotoxic effects) by interfering with structure and function of DNA that lead to cell death and inhibition of tumor growth.

Common side effects

Inflammation of a vein, Liver injury, Acute renal failure, Urinary bladder inflammation, Bleeding of the urinary bladder, Blood in urine, Bone marrow suppression, Hair loss, Infection, Loss of appetite, Nausea, Renal dysfunction, Vomiting, Reduced blood platelets, Decreased white blood cell count


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Expert advice for IFOXAN + MESNA

  • Drink at least 1 litre of fluid daily while you are receiving mesna.
  • Seek immediate medical attention if you experience severe allergic reactions like rash, itching, breathing difficulty, chest tightness, and swelling of the mouth, face, lips, or tongue while taking mesna.
  • Do not drive or operate machinery as mesna may cause drowsiness, dizziness, blurred vision, or light headedness.
  • Tell your doctor if you are pregnant or planning to become pregnant or are breastfeeding.
  • You will be monitored for blood or protein in urine during the treatment of mesna.
  • Do not take if allergic to mesna or any of its ingredients (thiol containing compound)

Frequently asked questions for IFOXAN + MESNA


Q. Is mesna a chemotherapy drug?
Mesna is not a chemotherapy drug.

Q. Why it is given with ifosamide or cyclophosphamise (Cytoxan)?
 It is given along with the chemotherapy drug ifosfamide or cyclophosphamide to reduce the side effects of these drugs.
Q. Is mesna cytotoxic?
No. Mesna is not cytotoxic drug. It is cytoprotective drug.
Q. Is mesna compatible with potassium chloride and doxorubicin?
Yes, Mesna is compatible with potassium chloride and doxorubicin.
Q. Is mesna a vesicant?
No, mesna is not a vesicant.


Q. Does ifosfamide cause hair loss or a vesicant?
Yes, ifosfamide may cause hair loss and it may act as vesicant.
Q. What is ifosfamide with mesna?
Ifosfamide may cause damage to urinary bladder therefore it is used in combination with mesna to prevent bleeding and inflammation of the urinary bladder (hemorrhagic cystitis).


Content on this page was last updated on 17 May, 2014, by Dr. Varun Gupta (MD Pharmacology)