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Composition FOR IFEX M

Mesna(1 gm),Ifosfamide(NA)

food interaction for IFEX M

alcohol interaction for IFEX M

pregnancy interaction for IFEX M

lactation interaction for IFEX M

There is no data available. Please consult doctor before consuming the drug.
Ifex m injection may cause excessive drowsiness and calmness with alcohol.
Ifex m injection is unsafe to use during pregnancy.
There is positive evidence of human fetal risk, but the benefits from use in pregnant women may be acceptable despite the risk, for example in life-threatening situations. Please consult your doctor.
Ifex m injection is probably unsafe to use during breastfeeding. Please consult your doctor.


Mesna(1 gm)


Mesna is used in the treatment of ovarian cancer, blood cancer, hemorrhagic cystitis and methotrexate toxicity

How it works

Mesna belongs toabdominal pain a class of drugs called cytoprotectants. It protects the urinary bladder from harmful effects of ifosfamide and cyclophosphamide.

Common side effects

Vomiting, Nausea, Drowsiness, Abdominal pain, Application site redness of skin, Application site irritation, Constipation, Cough, Diarrhoea, Fever, Fatigue, Dizziness, Flushing, Hair loss, Headache, Weight loss, Loss of appetite, Loss of strength, Muscle pain, Joint pain, Sore throat


Ifosfamide is used in the treatment of ovarian cancer, breast cancer, non-small cell lung cancer and blood cancer

How it works

Ifosfamide works by damaging the genetic material (DNA) of the cancer cells and stops their growth and multiplication.

Common side effects

Inflammation of a vein, Liver injury, Acute renal failure, Urinary bladder inflammation, Bleeding of the urinary bladder, Blood in urine, Bone marrow suppression, Hair loss, Infection, Loss of appetite, Nausea, Renal dysfunction, Vomiting, Reduced blood platelets, Decreased white blood cell count


No substitutes found

Expert advice FOR IFEX M

  • Drink at least 1 litre of fluid daily while you are receiving mesna.
  • Seek immediate medical attention if you experience severe allergic reactions like rash, itching, breathing difficulty, chest tightness, and swelling of the mouth, face, lips, or tongue while taking mesna.
  • Do not drive or operate machinery as mesna may cause drowsiness, dizziness, blurred vision, or light headedness.
  • Tell your doctor if you are pregnant or planning to become pregnant or are breastfeeding.
  • You will be monitored for blood or protein in urine during the treatment of mesna.
  • Do not take if allergic to mesna or any of its ingredients (thiol containing compound)

Frequently asked questions FOR IFEX M


Q. Is mesna a chemotherapy drug?
Mesna is not a chemotherapy drug

Q. Why it is given with ifosamide or cyclophosphamise (Cytoxan)?
It is given along with the chemotherapy drug ifosfamide or cyclophosphamide to reduce the side effects of these drugs

Q. Is mesna cytotoxic?
No. Mesna is not cytotoxic drug. It is cytoprotective drug

Q. Is mesna compatible with potassium chloride and doxorubicin?
Yes, Mesna is compatible with potassium chloride and doxorubicin

Q. Is mesna a vesicant?
No, mesna is not a vesicant.


Q. Does ifosfamide cause hair loss or a vesicant?
Yes, ifosfamide may cause hair loss and it may act as vesicant

Q. What is ifosfamide with mesna?
Ifosfamide may cause damage to urinary bladder therefore it is used in combination with mesna to prevent bleeding and inflammation of the urinary bladder (hemorrhagic cystitis).


Content on this page was last updated on 12 January, 2017, by Dr. Varun Gupta (MD Pharmacology)