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Ibanic 6 Injection

Written By Dr. Subita Alagh, BDS
Reviewed By Dr. Sachin Gupta, MD Pharmacology, MBBS
Last updated on 21 Sep 2025 | 05:27 PM (IST)
Ibanic 6 Injection is used to treat high levels of a mineral called calcium in people who have cancer. It is also used to treat or prevent weakening of the bones (osteoporosis) caused by menopause or the use of steroids. Using this medicine can reduce your risk of breaking bones.
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General Information

The content is shown in English
Ibanic 6 Injection image
Ibanic 6 Injection image

Product introduction

Ibanic 6 Injection is given by a doctor or nurse. You will not need to do this yourself. How much you are given, and how often, will be decided by your doctor. It may just be a single injection but if you are being treated for bone problems caused by the spread of cancer you may need regular injections. Your doctor will ask you to drink plenty of water before the injection, to avoid getting dehydrated. It may take several days to get the full benefit of this drug. Ibanic 6 Injection is only part of a program of treatment that may also include changes to your diet and taking calcium and vitamin supplements.

The most common side effects include headache, musculoskeletal (bone, muscle, or joint) pain, indigestion, heartburn, and diarrhea. These are usually mild and will disappear after a short time. If they do not go away, tell your doctor. Ibanic 6 Injection can cause serious kidney problems, especially if you are dehydrated, if you take diuretic medicine (water pills), or if you already have kidney disease. It can also cause low levels of calcium in the blood and pain in the mouth or jaw. These are serious side effects and need urgent medical attention. Tell your doctor straight away.

You should not be given this medicine if you are breastfeeding. Before taking it, tell your doctor if you have kidney problems or low calcium levels. Also, let your doctor know what other drugs you are taking. Some of them may affect, or be affected by, this injection, especially medicines used to treat severe infections and medicines used to treat cancer and osteoporosis. You may need frequent medical tests to check your kidney function and mineral levels. Avoid smoking or try to quit as smoking can reduce your bone mineral density, making fractures more likely. Drinking large amounts of alcohol can also cause bone loss and should be avoided.

Uses of Ibanic Injection

Benefits of Ibanic Injection

Hypercalcemia
Calcium is a mineral found in different places in your body and has many functions including bone growth. Most of your calcium should be in your bones. When you have more calcium in your blood than normal it is called hypercalcaemia (high blood calcium levels). It is a serious condition and affects a large number of people with cancer. Ibanic 6 Injection is a type of medicine called a bisphosphonate. It reduces the amount of calcium in your blood by slowing down the rate at which bone is broken down in your body. This medicine is normally only given once by injection to treat hypercalcaemia, but you may need additional doses. Make sure you attend all appointments with your doctor.

Being immobile makes hypercalcaemia worse. Whenever possible you should take regular exercise, especially weight-bearing exercise. Do not take calcium or vitamin D3 supplements and try to decrease your intake of these in your diet.
Osteoporosis
Osteoporosis is a common condition that weakens bones, making them fragile and more likely to break. It often occurs in women after menopause. This condition can be treated with bone-strengthening medicines. Ibanic 6 Injection is a type of medicine called a bisphosphonate. It slows down the rate at which bone is broken down in your body. This maintains bone density and reduces your risk of breaking a bone. The injection is usually given once every year to treat osteoporosis and every two years to prevent it.

You can help improve the strength of your bones by doing regular exercise (especially weight-bearing exercise), eating healthy foods containing calcium and Vitamin D, and reducing your consumption of alcohol and tobacco. Supplements of calcium and Vitamin D3 are also effective.

Side effects of Ibanic Injection

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Ibanic
  • Injection site reactions (pain, swelling, redness)
  • Headache
  • Musculoskeletal (bone, muscle or joint) pain
  • Heartburn
  • Diarrhea
  • Indigestion

How to use Ibanic Injection

Your doctor or nurse will give you this medicine. Kindly do not self administer.

How Ibanic Injection works

Ibanic 6 Injection is a bisphosphonate. It works by suppressing the activity of osteoclasts, cells that cause destruction of bone. This strengthens the bones and minimizes the risk of fractures.

Quick tips

  • It is given by injection into a vein, usually over 15-30 seconds or as directed by your doctor.
  • Drink plenty of fluids to prevent dehydration and kidney damage.
  • It can lower the level of calcium in the blood. Take calcium and vitamin D supplements as suggested by your doctor.
  • You may develop fever or flu-like symptoms, such as chills, tiredness, and weakness. These are usually temporary and should go away after a few days. You may take a pain reliever/fever reducer to prevent or treat these symptoms.
  • It may cause a rare condition called osteonecrosis of the jaw. Have regular dental check-ups and inform your doctor if you develop sudden pain in your jaw.
  • Your doctor will monitor your response to Ibanic 6 Injection by testing your bone mineral density (BMD). This is usually done every 1-3 years.
  • Do not take it if you are pregnant.

Safety advice

Alcohol

Alcohol

CAUTION
Caution is advised when consuming alcohol with Ibanic 6 Injection. Please consult your doctor.
Pregnancy

Pregnancy

CONSULT YOUR DOCTOR
Ibanic 6 Injection may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Breast feeding

Breast feeding

CONSULT YOUR DOCTOR
Information regarding the use of Ibanic 6 Injection during breastfeeding is not available. Please consult your doctor.
Driving

Driving

SAFE
Ibanic 6 Injection does not usually affect your ability to drive.
Kidney

Kidney

SAFE IF PRESCRIBED
Ibanic 6 Injection is safe to use in patients with kidney disease. No dose adjustment of Ibanic 6 Injection is recommended.
However, the use of Ibanic 6 Injection is not recommended in patients with severe renal impairment.
Liver

Liver

SAFE IF PRESCRIBED
Ibanic 6 Injection is probably safe to use in patients with liver disease. Limited data available suggests that dose adjustment of Ibanic 6 Injection may not be needed in these patients. Please consult your doctor.

Frequently asked questions

Ibanic 6 Injection belongs to a class of medicines called bisphosphonates that prevents abnormal breakdown of the bones. Ibanic 6 Injection is used to prevent and treat osteoporosis and fractures in people with metastatic cancer (a cancer which spreads to newer areas of the body). It may also be used to treat hypercalcemia (elevated blood calcium levels).
Ibanic 6 Injection works by increasing the density of the bones which helps prevent osteoporosis. Along with that, it helps to treat high calcium levels in the blood caused due to secondary bone cancer. It is also helpful in treating metastasis of bone which is caused due to breast cancer.
Ibanic 6 Injection should be taken in the dose and duration advised by your doctor. Usually Ibanic 6 Injection is prescribed for at least 6 months before it has the maximum effect on your bones. However, your doctor may continue your treatment for as long as Ibanic 6 Injection is working well for you.
Ibanic 6 Injection should be administered by a trained healthcare professional or a doctor only and should not be self-administered. The dose will depend on the condition you are being treated for and will be decided by your doctor. Follow your doctor’s instructions carefully to get maximum benefit from Ibanic 6 Injection.
Ibanic 6 Injection is safe if used in the dose and duration advised by your doctor. Take it exactly as directed and do not skip any dose. Follow your doctor's instructions carefully and let your doctor know if any of the side effects bother you.
To get maximum benefit from Ibanic 6 Injection, there are certain lifestyle changes that you must adhere to. Include some calcium or Vitamin D rich foods for bone strength. Try to spend more time in sunlight to get natural vitamin D. Quit smoking and reduce alcohol consumption as they may harm your bones. You can take up an exercise regime such as walking and low-impact aerobics as they are good for your bones. Similarly, you can try strength-training exercises where you use your own body weight which in turn improve bone health.

Fact Box

Chemical Class

Bisphosphonate Derivative

Habit Forming

No

Therapeutic Class

PAIN ANALGESICS

Action Class

Bone Resorption Inhibitors- Bisphosphonates

References

  1. Furst DE, Ulrich RW, Varkey-Altamirano C. Nonsteroidal Anti-Inflammatory Drugs, Disease Modifying Antirheumatic Drugs, Nonopioids Analgesics, & Drugs Used in Gout. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. p. 630.
  2. Vinetz JM, Clain J, Bounkeua V, Eastman RT, et al. Chemotherapy of Malaria. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. p. 1402-405.
  3. Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 669-71.
  4. Chaves RG, Lamounier JA. Breastfeeding and maternal medications. J Pediatr (Rio J). 2004;80(5 Suppl):S189-S198. [Accessed 02 Apr. 2019] (online) Available from:
  5. Central Drugs Standard Control Organisation (CDSCO). [Accessed 02 Apr. 2019] (online) Available from:
  6. Ibandronic acid bondronat [Product Information]. Akshar Pharma. [Accessed 05 Jul. 2023]. (online) Available from:
  7. Ibandronate Sodium Injection [Prescribing Information]. Tainan City, Taiwan: Nang Kuang Pharmaceutical Co., Ltd.; 2022. [Accessed 05 Jul. 2023]. (online) Available from:
  8. Drugs and Lactation Database (LactMed®) [Internet]. Bethesda (MD): National Institute of Child Health and Human Development; 2006. Ibandronate. [Updated 2021 Apr 19]. [Accessed 05 Jul. 2023]. (online) Available from:
  9. Central Drugs Standard Control Organisation. Ibandronic Acid. [Accessed 05 Jul. 2023]. (online) Available from:
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Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Axiommax Oncology Pvt Ltd
Address: A/303, Atrium -1, Andheri - Kurla Road, Mumbai – 400 059 India

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Country of origin: India
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