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25 Jul 2019 | 03:53 PM (IST)
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Hermab 150mg Injection


Overview

Introduction

Hermab 150mg Injection is used in the treatment of breast and stomach cancer.

Hermab 150mg Injection is given as an injection by a qualified medical professional. You should continue to take as long as your doctor advises for it. The duration of treatment varies according to your need and response to treatment. Your doctor will monitor your heart regularly while taking this medicine. Inform your doctor if you notice symptoms like breathlessness, cough, shivering, swelling of legs and arm after taking Hermab 150mg Injection.

You should use effective contraception method to prevent pregnancy while taking this medicine and after you stop the treatment (for 7 months). There are various side effects related to Hermab 150mg Injection such as sore throat, fever, chills, excessive tiredness, pale skin, and nosebleeds.

Uses of Hermab Injection

Side effects of Hermab Injection

Common
  • Nausea
  • Headache
  • Rash
  • Insomnia (difficulty in sleeping)
  • Infection
  • Upper respiratory tract infection
  • Fatigue
  • Fever
  • Anemia (low number of red blood cells)
  • Chills
  • Diarrhea
  • Cough
  • Weight loss
  • Taste change
  • Mucosal inflammation
  • Stomatitis (Inflammation of the mouth)
  • Heart failure
  • Decreased blood cells (red cells, white cells, and platelets)
  • Common cold

How to use Hermab Injection

Your doctor or nurse will give you this medicine. Kindly do not self administer.

How Hermab Injection works

Hermab 150mg Injection is a recombinant IgG1 monoclonal antibody. It works against the HER2 (human epidermal growth factor receptor protein) receptors which are responsible for the over-proliferation of cancer cells in breast cancer and stomach cancer cells. It destroys the cancer cells by inhibiting HER2. It also inhibits various cancer-causing downstream signaling pathways.

Safety Advice

Alcohol
UNSAFE
Hermab 150mg Injection may cause excessive drowsiness with alcohol.
Pregnancy
CONSULT YOUR DOCTOR
Hermab 150mg Injection is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.
Breastfeeding
CONSULT YOUR DOCTOR
Hermab 150mg Injection is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
Driving
CONSULT YOUR DOCTOR
It is not known whether Hermab 150mg Injection alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react.
Kidney
SAFE IF PRESCRIBED
Hermab 150mg Injection is probably safe to use in patients with kidney disease. Limited data available suggests that dose adjustment of Hermab 150mg Injection may not be needed in these patients. Please consult your doctor.
Liver
CONSULT YOUR DOCTOR
There is limited information available on the use of Hermab 150mg Injection in patients with liver disease. Please consult your doctor.

What if you forget to take Hermab Injection?

If you miss a dose of Hermab 150mg Injection, please consult your doctor.

Alternate Brands

For informational purposes only. Consult a doctor before taking any medicines.
Hermab 150mg Injection
₹19500.0/Injection
₹21430.5/ml of Injection
10% costlier
₹22447/Injection
15% costlier
Hertraz 150mg Injection
Mylan Pharmaceuticals Pvt Ltd
₹19500/Injection
same price
Trasturel 150mg Injection
Reliance Life Sciences
₹24200/Injection
24% costlier
Hersima 150mg Injection
Alkem Laboratories Ltd
₹19132.65/Injection
save 2%

Quick Tips

  • It is given as an injection into your vein or under the skin, usually over 1 hour.
  • Use effective contraception method to prevent pregnancy while taking this medicine and for 7 months after you stop the treatment. 
  • Your doctor will monitor your heart regularly while taking this medicine. Inform your doctor if you notice symptoms such as breathlessness, cough, shivering, swelling of legs and arm.
  • Inform your doctor if you are pregnant, planning pregnancy or breastfeeding. 

Patient Concerns

arrow
Any medicine to treat stage 4 breast cancer and strengthen immunity
Dr. Saurav Arora
Homeopathy
Dear mam you can safely take homeopathic treatment in your case, but as your case is chronic the treatment should be under monitoring of a physician
She has breast cancer at 4 sta
Dr. Rohan Khandelwal
Cancer Specialist
Dear PATIENT 4 Breast Cancer means that the cancer has spread to other parts of the body. The management of such cancers depends on the site where the cancer has spread and on the receptor status of the breast cancer. If you can share the details with me, I will be happy to let you know the potential management
arrow
Do you have any questions related to Hermab 150mg Injection ?

User Feedback


FAQs

Q. What are the serious side effects of Hermab?

There are various side effects related to Hermab such as sore throat, fever, chills, excessive tiredness, pale skin, nosebleeds, and other unusual bruising or bleeding. One can also experience stomach pain, seizures, hallucinations, muscle cramps, and spasms. Along with that, nausea or vomiting, loss of appetite, fatigue, rapid heart beat, discoloration of urine; decreased amount of urine, difficulty in urinating, pain when urinating, and other signs of infection can also be observed with the use of Hermab. You should call your doctor immediately if you notice any such symptoms.

Q. How long after Hermab therapy can I get pregnant?

Women of child-bearing age should use effective contraception during Hermab therapy and for 7 months after completing the treatment. You can plan your pregnancy after 7 months of treatment with Hermab.

Q. How long should Hermab be taken?

Patients with early breast cancer should take Hermab for 1 year or until disease recurs, whichever occurs first. It is not advised to extend the treatment beyond 1 year in patients of early breast cancer.

Q. Is fasting required before administering Hermab?

No, fasting is not required before administering Hermab. It should be given under the guidance of a doctor who is experienced in giving cancer chemotherapy and should be given only by a healthcare professional.

Q. How is Hermab given, intravenously or intramuscularly?

There are 2 different formulations available for administration of Hermab, one is given as an infusion into a vein (intravenous infusion) and the other is given as an injection under the skin (subcutaneous injection). It is important to check the product labels to ensure that the correct formulation is being given as prescribed. Hermab intravenous formulation is not for subcutaneous use and should be given as an intravenous infusion only. Your doctor may consider switching your Hermab intravenous treatment to Hermab subcutaneous treatment (and vice versa) if considered appropriate for you.

Q. Can Hermab be given to HER2 negative cancer patients?

No, Hermab cannot be given in patients with HER2 negative cancer cells. Hermab belongs to class of monoclonal antibody. It binds selectively to a protein called human epidermal growth factor receptor 2 (HER2). HER2 is found, in large amounts, on the surface of some cancer cells. When Hermab binds to HER2, it stops the growth and spread of the cancer cells. Therefore, it is only effective in HER2 positive patients (in which HER2 is present) and will not be beneficial for HER2 negative patients (in which HER2 is not present).

Q. Why has my doctor advised for investigations of heart?

Hermab when used with anthracycline class of anti-cancer medicines (eg doxorubicin) may adversely affect your heart. Hence, your doctor needs to check the health of your heart initially before starting treatment and during treatment.

Q. How frequently heart investigations are required?

Heart investigations should be performed at the starting of the treatment. It should be repeated every 3 months during treatment and every 6 months after the discontinuation of treatment until 24 months from the last administration of Hermab. Those patients who already have heart-related problems will require investigations every 12 weeks.

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Disclaimer: 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover all possible side effects, drug interactions or warnings or alerts. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.
References
  1. Chabner BA, Barnes J, Neal J, et al. Targeted Therapies: Tyrosine Kinase Inhibitors, Monoclonal Antibodies, and Cytokines. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. pp. 1737.
  2. Lake DF, Briggs AD, Akporiaye ET. Immunopharmacology. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. p. 978.
  3. Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 1390-91.
  4. Trastuzumab. South San Francisco, California: Genentech, Inc.; 1998 [revised Oct. 2010]. [Accessed 27 Mar. 2019] (online) Available from:External Link
  5. U.S. National Library of Medicine. Trastuzumab. [Accessed 27 Mar. 2019] (online) Available from:External Link
Manufacturer/Marketer Address
463, 4 th Floor, RPG HOUSE, Dr. Annie Besant Road, Worli, Mumbai – 400 030. Maharashtra, INDIA
A licensed pharmacy from your nearest location will deliver Hermab 150mg Injection. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your prescription and the availability of this medicine.
Best Price
₹15600
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1 Injection in 1 vial
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