







Harmoni-F Tablet
Cyproterone (2mg)+ Ethinyl Estradiol (0.035mg)+ Folic Acid (5mg)
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Harmoni-F Tablet is a combination medicine used in the treatment of polycystic ovarian syndrome (PCOS), as it helps to regularize the menstrual cycle. It also treats severe acne and hirsutism (excess hair growth, mainly on face and chest) in women.
Written By Dr. Lipika Khurana, PGDHHM, BDS,
Reviewed By Dr. Mekhala Chandra, MD, MBBS,
Last updated on 25 Nov 2025 | 03:07 PM (IST)
Written By Dr. Lipika Khurana, PGDHHM, BDS,
Reviewed By Dr. Mekhala Chandra, MD, MBBS,
Last updated on 25 Nov 2025 | 03:07 PM (IST)
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General Information
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Product introduction
Harmoni-F Tablet can be taken with or without food, but take it at the same time to get the most benefit. It should be taken as per your doctor's advice. The dose and how often you take it depends on what you are taking it for. Your doctor will decide how much you need to improve your symptoms. Swallow the tablets whole with a glass of water. You should take this medicine for as long as it is prescribed for you. It also works as a contraceptive, so better to avoid taking any other hormonal pills while taking this medicine.
The most common side effects of this medicine include nausea, stomach pain, headache, breast pain, and mood changes. If these bother you or appear serious, let your doctor know. There may be ways of reducing or preventing them. Usually, missing a dose may cause spotting or brown discharge in the middle of the cycle. Let your doctor know if this occurs frequently. Consult with your doctor immediately if you notice unexplained swelling and pain in your limbs, shortness of breath, chest pain or changes in vision. Do not continue with the medicine and consult with the doctor if your periods do not start within a week of the treatment.
Before taking this medicine, let your doctor know if you smoke and are over 35, or if you have ever had a heart attack or have cancer of uterus/cervix, or vagina. Your doctor should also know about all other medicines you are taking as many of these may make this medicine less effective or change the way it works. Avoid the use of medicine if you are pregnant or breastfeeding.
The most common side effects of this medicine include nausea, stomach pain, headache, breast pain, and mood changes. If these bother you or appear serious, let your doctor know. There may be ways of reducing or preventing them. Usually, missing a dose may cause spotting or brown discharge in the middle of the cycle. Let your doctor know if this occurs frequently. Consult with your doctor immediately if you notice unexplained swelling and pain in your limbs, shortness of breath, chest pain or changes in vision. Do not continue with the medicine and consult with the doctor if your periods do not start within a week of the treatment.
Before taking this medicine, let your doctor know if you smoke and are over 35, or if you have ever had a heart attack or have cancer of uterus/cervix, or vagina. Your doctor should also know about all other medicines you are taking as many of these may make this medicine less effective or change the way it works. Avoid the use of medicine if you are pregnant or breastfeeding.
Uses of Harmoni-F Tablet
Benefits of Harmoni-F Tablet
Polycystic ovarian syndrome (PCOS)
Polycystic ovarian syndrome (PCOS) is a condition that causes hormonal imbalance in women. This leads to irregular menstrual cycles (periods), excessive hair growth and acne. Harmoni-F Tablet helps in regulating hormonal imbalance as well as periods in females and thus reduces the symptoms associated with PCOS. Take it as prescribed by the doctor. Do not skip any doses and follow your doctor’s instructions carefully to get maximum benefit.
Polycystic ovarian syndrome (PCOS) is a condition that causes hormonal imbalance in women. This leads to irregular menstrual cycles (periods), excessive hair growth and acne. Harmoni-F Tablet helps in regulating hormonal imbalance as well as periods in females and thus reduces the symptoms associated with PCOS. Take it as prescribed by the doctor. Do not skip any doses and follow your doctor’s instructions carefully to get maximum benefit.
Side effects of Harmoni-F Tablet
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Harmoni-F
- Nausea
- Stomach pain
- Headache
- Breast pain
- Mood changes
How to use Harmoni-F Tablet
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Harmoni-F Tablet may be taken with or without food.
How Harmoni-F Tablet works
Harmoni-F Tablet is a combination of two hormonal medicines: Cyproterone and Ethinyl Estradiol, and Folic Acid which treat PCOS symptoms such as acne, excessive hair growth (hirsutism) and irregular menstrual cycle (periods). Cyproterone works by blocking the overproduction of androgens (male hormones) in the ovaries thereby reducing unwanted hair growth and acne. Ethinyl Estradiol enhances the effect of Cyproterone by reducing the amount of androgens in the blood circulation. Folic Acid is a form of vitamin B. It plays a vital role in the formation of red blood cells, which carry oxygen throughout the body. It is also used to treat or prevent low folate levels due to poor diet. Together, they also regularize the menstrual cycle in PCOS.
Quick tips
- Your doctor has prescribed Harmoni-F Tablet to treat symptoms of polycystic ovary syndrome (PCOS) such as excessive hair growth (hirsutism), acne and irregular menstrual cycle (periods).
- Take your pill at the same time every day to help you remember to take it.
- Do not use Harmoni-F Tablet if you are obese, over 50, smoke, on prolonged bed rest, or have a history of blood clots.
- Stop taking it and inform your doctor if you notice unexplained swelling and pain in your limbs, shortness of breath, chest pain, or changes in vision.
- You may experience vaginal spotting (blood stain) or breakthrough bleeding while taking Harmoni-F Tablet. This is temporary, inform your doctor if it lasts longer.
- If your period fails to come within a week after completing your course, don’t start the next course, before consulting your doctor.
- Do not use additional hormonal contraceptives when taking Harmoni-F Tablet, as it works as a contraceptive.Â
Safety advice

Alcohol
CAUTION
Alcohol should be used with caution while taking Harmoni-F Tablet.

Pregnancy
UNSAFE
Harmoni-F Tablet is highly unsafe during pregnancy. It can cause serious harm to the unborn baby, including birth defects and pregnancy loss. Do not use this medicine if you are pregnant or planning to become pregnant.

Breast feeding
UNSAFE
Harmoni-F Tablet is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.

Driving
UNSAFE
Harmoni-F Tablet may decrease alertness, affect your vision, or make you feel sleepy and dizzy. Do not drive if these symptoms occur.

Kidney
SAFE IF PRESCRIBED
Harmoni-F Tablet is probably safe to use in patients with kidney disease. Limited data suggest dose adjustment may not be needed.

Liver
SAFE IF PRESCRIBED
Harmoni-F Tablet is probably safe to use in patients with liver disease. Limited data suggest dose adjustment may not be needed.
Frequently asked questions
Harmoni-F Tablet is a combination of two hormonal medicines Cyproterone and Ethinyl Estradiol along with folic acid. It treats PCOS symptoms such as acne, excessive hair growth (hirsutism) and irregular periods. Cyproterone works by blocking the overproduction of androgens (male hormones) in the ovaries, thereby reducing unwanted hair growth and acne. Ethinyl Estradiol enhances the effect of Cyproterone by reducing the amount of androgens in the blood circulation.
Harmoni-F Tablet has to be started on day 1 or 2 of your natural cycle (first day of menstrual bleeding). Take it as per the duration advised by your doctor. However, it is recommended to take it at the same time each day. This will ensure consistent levels of medicine in your body.
If you miss a dose, you should take it as soon as possible. If the dose was missed by more than 12 hours, you should not take the missed dose and simply continue the usual dosing schedule. However, to prevent pregnancy another non-hormonal birth control (like condoms) method should be used during this cycle. Frequent missing of dose, may also cause unexpected vaginal bleeding or spotting (blood stain). If it lasts long, consult your doctor.
If vomiting occurs within 3-4 hours of taking the tablet, you must repeat the dose.
Yes, if taken as advised, Harmoni-F Tablet also act as a contraceptive. Discontinue using any other birth control pills while taking Harmoni-F Tablet.
The most common side effects associated with Harmoni-F Tablet are nausea, stomach pain, increased weight, headache, altered mood, and breast pain. Most of these symptoms are temporary. However, if they persist, check with your doctor as soon as possible.
Usually, you will be able to notice improvements in 3-4 weeks. However, it is important to finish the full course of treatment to see its full benefit. Inform your doctor if your acne did not get cured even after finishing the full course of treatment.
Fact Box
Habit Forming
No
Therapeutic Class
GYNAECOLOGICAL
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User feedback
Once A Day
97%
Once A Month
3%
Twice A Day
1%
Polycystic ovarian syndrome (PCOS)
80%
Others
15%
Contraception
3%
Post menopausal osteoporosis
2%
Average
48%
Poor
28%
Excellent
23%
Nausea
27%
No Side Effect
24%
Headache
24%
Mood changes
5%
Stomach pain
5%
With food
79%
With or without food
18%
Empty stomach
3%
Expensive
47%
Average
39%
Not Expensive
14%
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Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.
Marketer details
Name: Alembic Pharmaceuticals Ltd
Address: Alembic Road, Vadodara - 390 003, Gujarat,INDIA
Address: Alembic Road, Vadodara - 390 003, Gujarat,INDIA
Vendor Details
Country of origin: India
Lab tests offered by us
- CBC (Complete Blood Count)
- FBS (Fasting Blood Sugar)
- Thyroid Profile Total (T3, T4 & TSH)
- HbA1c (Glycosylated Hemoglobin)
- PPBS (Postprandial Blood Sugar)
- Lipid Profile
- Vitamin D (25-Hydroxy)
- Urine R/M (Urine Routine & Microscopy)
- Coronavirus Covid -19 test- RT PCR
- LFT (Liver Function Test)
- KFT (Kidney Function Test)
- TSH (Thyroid Stimulating Hormone) Ultrasensitive
- ESR (Erythrocyte Sedimentation Rate)
- Uric Acid, Serum
- Vitamin B12
- CRP (C-Reactive Protein), Quantitative
- Urine C/S (Urine Culture and Sensitivity)
- Serum Electrolytes
- Serum Calcium
- Serum Creatinine
- Diabetes Screening (HbA1C & Fasting Sugar)
- KFT with Electrolytes (Kidney Function Test with Electrolytes)
- Cholesterol - Total
- Hb (Hemoglobin)
- Complete Hemogram (CBC & ESR)
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