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Granirex Injection

Granisetron (1mg/ml)
Genuine
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Granirex Injection is an antiemetic medicine used to prevent and treat nausea and vomiting caused by chemotherapy, radiotherapy, or surgical procedures. Granirex Injection works by blocking certain chemical in the brain that triggers vomiting signals, especially during chemotherapy.

Written By Dr. Syeda Aafia, MBA, BDS,
Reviewed By Dr. Rajeev Sharma, MBA, MBBS,
Last updated on 26 Dec 2025 | 05:16 PM (IST)
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Granirex Injection image
Granirex Injection image

Product introduction

Granirex Injection will not relieve other side effects associated with cancer treatments. It is administered under the supervision of a healthcare professional and should be taken as advised by the doctor. It is important that you keep having the injections until your doctor decides it is safe to stop them. After this, your doctor may prescribe tablets instead of injections.


The most common side effects of taking this medicine include injection site pain or reaction, headache, constipation, diarrhea, and weakness. These symptoms should disappear when you stop taking the medicine, but if they bother you or do not go away, your doctor may be able to suggest ways of preventing or reducing them.


Before taking this medicine, tell your doctor if you have heart or liver problems or a blockage in your stomach or intestines. Als,o tell your doctor about other drugs you are using, especially medicines to treat epilepsy, heart problems, cancer, and depression. These may affect, or be affected by, this medicine. If you are pregnant or breastfeeding, ask for advice from your doctor.

Uses of Granirex Injection

  • Treatment of Nausea and vomiting due to chemotherapy

Benefits of Granirex Injection

Treatment of Nausea and vomiting due to chemotherapy
Granirex Injection blocks the action of chemicals in the body that can make you feel or be sick. It is often used to prevent nausea and vomiting associated with cancer treatment such as chemotherapy or radiation therapy. This medicine helps you recover more comfortably from these treatments.

Side effects of Granirex Injection

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Granirex
  • Injection site pain
  • Constipation
  • Diarrhea
  • Headache
  • Weakness
  • Insomnia (difficulty in sleeping)

How to use Granirex Injection

Your doctor or nurse will give you this medicine. Kindly do not self administer.

How Granirex Injection works

Granirex Injection is an antiemetic medication. It works by blocking the action of a chemical messenger (serotonin) in the brain that may cause nausea and vomiting during anti-cancer treatment (chemotherapy).

All substitutes for Granirex Injection

For information purposes only. Consult a doctor before taking any medicine.

Quick tips

  • Take meals in small, frequent portions and avoid heavy, greasy, or spicy foods to reduce nausea while on Granirex Injection.
  • Stay hydrated with small, frequent sips of water or electrolyte fluids, especially if vomiting has occurred.
  • Inform your doctor if you are taking other medicines that affect heart rhythm, as Granirex Injection can influence cardiac conduction in rare cases.
  • Do not drive or perform tasks requiring alertness if you feel dizzy or lightheaded after receiving Granirex Injection.
  • Report any persistent headache, constipation, or abdominal discomfort to your doctor if symptoms do not improve.

Safety advice

Alcohol

Alcohol

CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with Granirex Injection. Please consult your doctor.
Pregnancy

Pregnancy

SAFE IF PRESCRIBED
Granirex Injection is generally considered safe to use during pregnancy. Animal studies do not indicate harmful effects. However, there are limited human studies.
Breast feeding

Breast feeding

SAFE IF PRESCRIBED
Granirex Injection may be safe to use during breastfeeding. Animal studies have shown low or no adverse effects to the developing baby; however, there are limited human studies.
Driving

Driving

SAFE
Granirex Injection does not usually affect your ability to drive.
Kidney

Kidney

SAFE IF PRESCRIBED
Granirex Injection is probably safe to use in patients with kidney disease. Limited data suggest dose adjustment may not be needed.
Liver

Liver

SAFE IF PRESCRIBED
Granirex Injection is probably safe to use in patients with liver disease. Limited data suggest dose adjustment may not be needed.

Interaction with drugs

Taking Granirex with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
Severe

Venlafaxine (Oral Route)

Watch out for symptoms such as tremors, fever, diarrhea or agitation and consult your doctor if you experience them. Factors such as old age, chronic heart issues, or low potassium levels may more frequently cause disturbance in heart rhythm, and your doctor may consider ECG monitoring in their presence. Your doctor may discontinue the medicines accordingly.
Severe

Apomorphine (Sublingual route)

Do not consume Apomorphine with Granisetron. If concurrent use is essential, please consult your doctor.
Severe

Apomorphine (Injection Route)

Do not consume Apomorphine with Granisetron. If concurrent use is essential, please consult your doctor.
Moderate

Chloroquine (Oral Route)

Careful consideration is advised when taking Chloroquine with Granisetron. Your doctor may monitor your treatment and adjust the doses as per the observations. Factors such as old age, chronic heart issues, or low potassium levels may more frequently cause disturbance in heart rhythm, and your doctor may consider ECG monitoring in their presence.
Moderate

Loperamide (Oral Route)

Careful consideration is advised when taking Loperamide with Granisetron. Your doctor may monitor your treatment and adjust the doses as per the observations. Factors such as old age, chronic heart issues, or low potassium levels may more frequently cause disturbance in heart rhythm, and your doctor may consider ECG monitoring in their presence.

Frequently asked questions

Granirex Injection is an antiemetic medicine used to treat and prevent nausea or vomiting caused after any surgical procedure or due to certain medicines, stomach upset, or cancer treatment. It also prevents nausea due to motion sickness to some extent.
The most common side effects of Granirex Injection are sleepiness, weakness, headache, constipation and diarrhea. However, these are not usually bothersome and resolve in some time on their own. Consult your doctor, if the symptoms worry you or persist for a longer duration. Your doctor will suggest ways to cope up with these side effects and to prevent them in future.
Granirex Injection did not show any adverse effects in research studies done on animals. However, since the safety and efficiency of Granirex Injection in pregnant women is unknown. It is not recommended to be used in women who are pregnant women or if you are planning to conceive unless prescribed by your doctor.
Granirex Injection and Ondansetron belong to the same class of medicines, that is serotonin 5-HT3 receptor antagonists. Both these medicines help prevent nausea and vomiting effectively. However, some studies suggest that Granirex Injection is more effective than Ondansetron. According to some reports, Granirex Injection is comparatively well tolerated, quicker in action and alleviates nausea and vomiting relatively faster.
Yes, Granirex Injection may cause constipation as one of the common side effects. However, this is usually not bothersome. Taking a fiber-rich diet can enhance your digestion and avoid constipation. You may also consider taking laxatives for relief and drink plenty of water too. Avoid drinking alcohol as it may worsen your constipation. If you still face issues, please consult your doctor to know about ways to treat it.

Fact Box

Chemical Class

Indazole- 3- carboxamides

Habit Forming

No

Therapeutic Class

GASTRO INTESTINAL

Action Class

Serotonin 5-HT3 Receptor Antagonists
100% genuine products
100% genuine products
Safe & secure payments
Safe & secure payments
No contact delivery
No contact delivery
Fully sanitized facilities
Fully sanitized facilities
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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Bennet Pharmaceuticals Limited
Address: 6th Floor, “B” Wing, Manubhai Towers,Sayajigunj, Vadodara - 390005 Gujarat. India

Vendor Details

Country of origin: India
A licensed vendor partner from your nearest location will deliver Granirex Injection. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's ℞ and the availability of this medicine.

In case of any issues, contact us

Email ID: [email protected]
Phone Number: 0124-4166666
Address: 5th Floor Tower - B of the Presidency Building, 46/4 Mehrauli Gurgaon Road, Sector 14, Gurugram, Haryana-122001, India
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