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MD (Pharmacology), MBBS
Last updated:
22 Jul 2020 | 06:00 PM (IST)
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Granirex 2mg Tablet

Prescription Required
SALT COMPOSITION
Storage
Store at room temperature (10-30°C)

Overview

Introduction

Granirex 2mg Tablet is an antiemetic medicine commonly used to control nausea and vomiting due to certain medical conditions like stomach upset. It is also used to prevent nausea and vomiting caused due to any surgery, cancer drug therapy or radiotherapy.

Granirex 2mg Tablet will not relieve other side effects associated with cancer treatments. It also has little effect on vomiting caused by motion sickness. You should take this medicine in the dose and duration advised by your doctor. But, it is better to take this medicine at a fixed time. Remember, you should not stop taking this medicine suddenly without talking to your doctor. In case you vomit within one hour of taking a dose, then take another dose and avoid heavy meals throughout the day.

The most common side effects of taking this medicine include headache, constipation, diarrhea, and weakness. Dizziness and sleepiness may also occur, so do not drive or do anything that requires mental focus until you know how this medicine affects you. These symptoms should disappear when you stop taking the medicine but if they bother you or do not go away, your doctor may be able to suggest ways of preventing or reducing them.

Before taking this medicine, tell your doctor if you have heart or liver problems or a blockage in your stomach or intestines. Also, tell your doctor about any other medicine that you might be using, especially medicines to treat epilepsy, heart problems, cancer, and depression. These may affect, or be affected by, this medicine. If you are pregnant or breastfeeding, ask for advice from your healthcare team.

Uses of Granirex Tablet

Benefits of Granirex Tablet

In Nausea

Granirex 2mg Tablet blocks the action of chemicals in the body that can make you feel or be sick. It is often used to prevent nausea and vomiting that may be caused by cancer chemotherapy and radiation treatment (in adults and children). It is usually taken both before and after chemotherapy or radiation. This medicine helps you recover more comfortably from these treatments. It is also effective at preventing nausea and vomiting after an operation (in adults only). The dose will depend on what you are being treated for but always take this medicine as it is prescribed.

Side effects of Granirex Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Granirex

  • Sleepiness
  • Weakness
  • Headache
  • Constipation
  • Diarrhea

How to cope with side effects?

The occurrence of side effects varies from person to person. The following are a few ways of dealing with some of the common side effects. However, consult your doctor if these persist.

  • Coping with Sleepiness
    If the medicine is making you drowsy during the day, stop what you are doing and sit or lie down until you feel better. You can also consider taking a nap. Physical exercises such as walking may be helpful. Do not drink alcohol, as it will make you feel more tired. Avoid driving or operating heavy equipment when you are feeling drowsy. This problem usually goes away as your body gets used to the medicine. However, if it does not, ask your doctor if you can take your medicine at bedtime or whether the dose can be reduced.
  • Coping with Weakness
    Make sure you rest and drink plenty of fluids. Eat a well-balanced diet to keep your energy levels up. Do not drink too much alcohol. Do not drive or use tools or machinery until you feel better. Other things that can help include doing some gentle exercise every day, prioritizing and pacing your activities and having a short nap if you need to. If you are still having problems after a week, speak to your doctor, as they may want to change you to a different type of medicine.
  • Coping with Headache
    Make sure you rest and drink plenty of fluids. Rest in a quiet, dimly lit room. Do not sleep more than you normally would. Do not strain your eyes (for example by looking at a screen). Do not drink alcohol. Headaches are usually temporary and usually go away with time. But, if they last longer or get worse, ask your doctor to recommend a painkiller.
  • Coping with Constipation
    Try to eat foods which are high in fiber such as fresh fruits, vegetables and cereals to increase the bulk and consistency of bowel movements. Drink plenty of water or non-alcoholic drinks and stay hydrated to promote healthy digestion. Increasing physical activities such as walking, yoga and regular exercise can also be helpful. If your condition does not improve, you can ask your doctor to prescribe you laxative medicine.
  • Coping with Diarrhea
    Keep up your intake of fluids and electrolytes (sugars and salts) to avoid getting dehydrated. Eat less fiber (avoid raw fruits, fruit juice and vegetables). Talk to your doctor about possible medication to manage diarrhea. Ask about reducing the dosage of your drug or other suitable treatments.

How to use Granirex Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Granirex 2mg Tablet may be taken with or without food, but it is better to take it at a fixed time.

How Granirex Tablet works

Granirex 2mg Tablet is an antiemetic medication. It works by blocking the action of a chemical messenger (serotonin) in the brain that may cause nausea and vomiting during anti-cancer treatment (chemotherapy) or after surgery.

Safety Advice

Alcohol
CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with Granirex 2mg Tablet. Please consult your doctor.
Pregnancy
SAFE IF PRESCRIBED
Granirex 2mg Tablet is generally considered safe to use during pregnancy. Animal studies have shown low or no adverse effects to the developing baby; however, there are limited human studies.
Breastfeeding
SAFE IF PRESCRIBED
Granirex 2mg Tablet is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.
Driving
SAFE
Granirex 2mg Tablet does not usually affect your ability to drive.
Kidney
SAFE IF PRESCRIBED
Granirex 2mg Tablet is probably safe to use in patients with kidney disease. Limited data available suggests that dose adjustment of Granirex 2mg Tablet may not be needed in these patients. Please consult your doctor.
Liver
SAFE IF PRESCRIBED
Granirex 2mg Tablet is probably safe to use in patients with liver disease. Limited data available suggests that dose adjustment of Granirex 2mg Tablet may not be needed in these patients. Please consult your doctor.

What if you forget to take Granirex Tablet?

If you miss a dose of Granirex 2mg Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

Alternate Brands

For informational purposes only. Consult a doctor before taking any medicines.
Granirex 2mg Tablet
₹7.26/Tablet
Spentron 2mg Tablet
Swati Spentose Pvt Ltd
₹12/Tablet
65% costlier

Quick Tips

  • You have been prescribed Granirex 2mg Tablet for prevention of nausea and vomiting caused after surgery or due to chemotherapy and radiotherapy.
  • Unlike some other nausea medicines, the side effects for Granirex 2mg Tablet are relatively mild.
  • It is fast-acting and starts working within 30 minutes.
  • If you vomit within one hour of taking a dose, take another dose.
  • Avoid heavy meals and try eating small nourishing snacks throughout the day. Also, sip water regularly to help avoid dehydration.

Fact Box

Chemical Class
Indazole Derivative
Habit Forming
No

Interaction with Drugs

Taking Granirex with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
Brand(s): Montokuf, Codine Sulphate, Codeine Phosphate
SERIOUS
Brand(s): Parvodex
SERIOUS
Brand(s): Nalfy, Nacphin, Ruffy
SERIOUS
Brand(s): Wintal
SERIOUS

Patient Concerns

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She is doing vomiting since 5pm today. Doctor has given GRANIREX for it. Only water is being given to her. But water is not staying in stomach. Stomach is also slightly filled with gas on left side.
Dr. Gopal Samdani
Paediatrics
There are many underlying causes of Patient?s symptoms. Different cause needs different treatment. Specific treatment cannot be given unless we establish exact underlying cause. Final and perfect diagnosis cannot be done without doing clinical examination of patient. Please consult me or any other Paediatrician. will take detail history and will examine patient in detail. All information will be used to determine exact underlying cause of problem. Depending upon cause will give opinion and prescribe you treatment. At time may ask you relevant investigations if necessary.
My wife is 13 week pregnent her docter change her tablet from mvista to doxynate plus me I know the reason is both tablet aee same. Docter asked to taje doxynate plus 2 tablet at bed time.please suggest.
Dr. Megha Tuli
Obstetrics and Gynaecology
Doxynate is tablet to stop vomiting dear. It is ok to take them at bed time. It is widely recommended to take for nausea and vomiting of pregnancy.
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Do you have any questions related to Granirex 2mg Tablet ?

User Feedback


FAQs

Q. What is Granirex used for?

Granirex is an antiemetic medicine used to treat and prevent nausea or vomiting caused after any surgical procedure or due to certain medicines, stomach upset, or cancer treatment. It also prevents nausea due to motion sickness to some extent.

Q. What are the side effects of Granirex?

The most common side effects of Granirex are sleepiness, weakness, headache, constipation and diarrhea. However, these are not usually bothersome and resolve in some time on their own. Consult your doctor, if the symptoms worry you or persist for a longer duration. Your doctor will suggest ways to cope up with these side effects and to prevent them in future.

Q. Is Granirex safe to be used in pregnant women?

Granirex did not show any adverse effects in research studies done on animals. However, since the safety and efficiency of Granirex in pregnant women is unknown. It is not recommended to be used in women who are pregnant women or if you are planning to conceive unless prescribed by your doctor.

Q. Is Granirex better than Ondansetron?

Granirex and Ondansetron belong to the same class of medicines, that is serotonin 5-HT3 receptor antagonists. Both these medicines help prevent nausea and vomiting effectively. However, some studies suggest that Granirex is more effective than Ondansetron. According to some reports, Granirex is comparatively well tolerated, quicker in action and alleviates nausea and vomiting relatively faster.

Q. Does Granirex cause constipation?

Yes, Granirex may cause constipation as one of the common side effects. However, this is usually not bothersome. Taking a fiber-rich diet can enhance your digestion and avoid constipation. You may also consider taking laxatives for relief and drink plenty of water too. Avoid drinking alcohol as it may worsen your constipation. If you still face issues, please consult your doctor to know about ways to treat it.

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1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover all possible side effects, drug interactions or warnings or alerts. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

References

  1. Granisetron. Hertfordshire: Generics [UK] Limited; 2005 [revised Nov. 2018]. [Accessed on 28 Mar. 2018] (online) Available from:External Link
  2. Drugs.com. Granisetron Pregnancy and Breastfeeding Warnings. [Accessed 28 Mar. 2019] (online) Available from:External Link
  3. Central Drugs Standard Control Organisation (CDSCO). [Accessed 28 Mar. 2019] (online) Available from:External Link

Manufacturer/Marketer Address

6th Floor, “B” Wing, Manubhai Towers,Sayajigunj, Vadodara - 390005 Gujarat. India
Country of Origin: India
Best Price
₹61.71
MRP72.6  Get 15% OFF
Valid only on the orders above ₹500
10 tablets in 1 strip
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