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Gramonex Injection is a combination of two antibiotics that effectively treat diarrhea and dysentery. It kills the microorganisms to treat the infection.

Written By Dr. Anuj Saini, MMST, MBBS,
Reviewed By Dr. Rajeev Sharma, MBA, MBBS,
Last updated on 12 Mar 2026 | 04:24 PM (IST)
₹109 MRP ₹120.9410% off 
As per Ministry of Health and Family Welfare
 
 
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Gramonex Injection image
Gramonex Injection image

Product introduction

Gramonex Injection is a prescription medicine that must be administered under the supervision of a healthcare professional. Do not miss any scheduled appointments for taking this medicine. The treatment must be completed even if you feel better to ensure a complete recovery.

Gramonex Injection may lead to some side effects such as nausea, vomiting, stomach pain, loss of appetite, headache, etc. To overcome any such side effects, it is advised to eat a healthy balanced diet and drink plenty of fluid. You may also experience mild injection site reactions such as pain, swelling, and redness. If any of the side effects get aggravated, contact your doctor immediately. If you experience any allergic reaction (rashes, itching, swelling, shortness of breath, etc.), you must seek immediate medical help.

Before taking this medicine, you should tell your doctor if you have any problems with your liver or kidneys. Also, tell your doctor if you are on any medication for any health condition. Pregnant or breastfeeding women should also consult with the doctors before taking it. Avoid drinking alcohol as it can cause excessive dizziness with this medicine. It usually does not impair your ability to drive, but you should not drive if it makes you feel sleepy or dizzy. If you are a known allergic to the medicine, you must refrain from using this medicine and consult your doctor. It is advised to take proper rest during the course of treatment for the medicine to work effectively.

Uses of Gramonex Injection

Benefits of Gramonex Injection

Diarrhea
Diarrhea is a condition where a person passes loose or watery stools frequently, often caused by bacterial infections. This can lead to dehydration, weakness, and discomfort. Gramonex Injection helps fight the infection, control the symptoms, and restore normal bowel function, improving overall comfort and recovery.
Dysentery
Dysentery is a more severe form of intestinal infection, often marked by diarrhea with blood or mucus, stomach pain, and fever. If not treated, it can lead to serious complications. Gramonex Injection helps clear the infection, reduce inflammation in the intestines, and ease symptoms, helping patients recover faster and avoid complications.

Side effects of Gramonex Injection

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Gramonex
  • Nausea
  • Dryness in mouth
  • Metallic taste
  • Headache

How to use Gramonex Injection

Your doctor or nurse will give you this medicine. Kindly do not self administer.

How Gramonex Injection works

Gramonex Injection is a combination of two antibiotics: Nalidixic Acid and Metronidazole. Nalidixic Acid works by preventing the bacterial cells from dividing and repairing, thereby killing the bacteria. Metronidazole kills parasites and anaerobic bacteria that cause infections by damaging their DNA. Together, they treat your infection effectively.

Quick tips

  • Your doctor has prescribed this combination medicine for the treatment of diarrhea and dysentery.
  • Diarrhea can cause dehydration. Drink plenty of fluids to help rehydrate you. 
  • Consult your doctor if your diarrhea lasts for more than 48 hours.
  • Do not use Gramonex Injection if you have blood in your stool or if you are severely constipated.
  • It may cause dizziness and sleepiness. Do not drive or do anything that requires mental focus until you know how it affects you.
  • Avoid consuming alcohol when taking Gramonex Injection as it may irritate your stomach and also cause excessive drowsiness.
  • Notify your doctor if you feel pain in your tendons, numbness, or tingling sensations.
  • Inform your doctor if you are pregnant or planning to conceive or breastfeeding.
  • Your doctor has prescribed this combination medicine for the treatment of diarrhea and dysentery.
  • Diarrhea can cause dehydration. Drink plenty of fluids to help rehydrate you. 
  • Consult your doctor if your diarrhea lasts for more than 48 hours.
  • Do not use Gramonex Injection if you have blood in your stool or if you are severely constipated.
  • It may cause dizziness and sleepiness. Do not drive or do anything that requires mental focus until you know how it affects you.
  • Avoid consuming alcohol when taking Gramonex Injection as it may irritate your stomach and also cause excessive drowsiness.
  • Notify your doctor if you feel pain in your tendons, numbness, or tingling sensations.
  • Inform your doctor if you are pregnant or planning to conceive or breastfeeding.

Safety advice

Alcohol

Alcohol

UNSAFE
Consumption of alcohol with Gramonex Injection may cause a disulfiram-like reaction, leading to symptoms such as flushing, increased heart rate, low blood pressure, nausea, lightheadedness, and severe headache.
Pregnancy

Pregnancy

CONSULT YOUR DOCTOR
The safety of Gramonex Injection during pregnancy has not been established. There are no adequate and well-controlled studies in pregnant women, and animal data on reproductive toxicity are insufficient. Your doctor will weigh the benefits and any potential risks before prescribing.
Breast feeding

Breast feeding

CAUTION
Gramonex Injection should be used with caution during breastfeeding. Breastfeeding should be held until the treatment of the mother is completed and the drug is eliminated from the body.
If a single dose of Gramonex Injection is used, it is recommended to hold breastfeeding for 12-24 hours to allow the removal of the drug.
Driving

Driving

UNSAFE
Gramonex Injection may cause side effects that could affect your ability to drive.
Gramonex Injection may make you feel sleepy, dizzy, confused. You may have hallucinations, fits (convulsions) or temporary eyesight problems (such as blurred or double vision) affecting your ability to drive.
Kidney

Kidney

CAUTION
Gramonex Injection should be used with caution in patients with kidney disease. Dose adjustment may be needed.
Regular monitoring of kidney function tests is advised if this medicine is to be taken for a long time.
Liver

Liver

CAUTION
Gramonex Injection should be used with caution in patients with liver disease. Dose adjustment may be needed.

Frequently asked questions

Inform your doctor if you don't feel better after finishing the full course of treatment. Also, inform him if your symptoms are getting worse while using this medicine.
No, do not stop taking Gramonex Injection and complete the full course of treatment even if you are feeling better. Your symptoms may improve before the infection is completely cured.
Take Gramonex Injection as soon as you remember it. However, do not take it if it's almost time for your next dose. Also, do not take an extra dose to make up for your missed dose.

Fact Box

Habit Forming

No

Therapeutic Class

GASTRO INTESTINAL

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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Nippon Seiyaku Pvt Ltd
Address: 514 - 515 ILD Tower Sohna Road Sec- 47 , Gurgaon, India

Vendor Details

Country of origin: India
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