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food interaction for GRAMONEX

alcohol interaction for GRAMONEX

pregnancy interaction for GRAMONEX

lactation interaction for GRAMONEX

food
alcohol
pregnancy
lactation
Avoid Gramonex injection with grapefruit juice.
UNSAFE
Gramonex injection may cause symptoms such as flushing, increased heartbeat, nausea, thirst, chest pain and low blood pressure with alcohol (Disulfiram reactions).
UNSAFE
Gramonex injection may be unsafe to use during pregnancy.
Animal studies have shown adverse effects on the foetus, however, there are limited human studies. The benefits from use in pregnant women may be acceptable despite the risk. Please consult your doctor.
WEIGH RISKS VS. BENEFITS
Unknown. Human and animal studies are not available. Please consult your doctor.

SALT INFORMATION FOR GRAMONEX

Nalidixic Acid(1.5 gm)

Uses

Nalidixic Acid is used in the treatment of bacterial infections

How it works

Nalidixic Acid is an antibiotic. It kills bacteria by inhibiting the DNA replication.

Common side effects

Nausea, Pain, Rash, Changes in color vision, Convulsion, Decreased pain sensitivity, Diarrhoea, Dizziness, Drowsiness, Headache, Increased body temperature, Skin redness, Stomach discomfort, Stomach pain, Inflammation of tendons, Vertigo, Vomiting, Weakness
Metronidazole(NA)

Uses

Metronidazole is used in the treatment of diarrhoea and bacterial infections

How it works

Metronidazole is an antibiotic. It kills the bacteria that cause infections.

Common side effects

Joint pain, Angioedema (swelling of deeper layers of skin), Throat irritation, Nasal congestion, Vomiting, Weakness, Allergic reaction, Dry mouth, Nausea, Skin irritation, Coating on tongue, Numbness, Loss of appetite, Fever, Itching, Furry tongue, Dry skin, Diarrhoea, Dark colored urine, Skin rash, Altered taste, Urticaria, Bitter taste, Stomach upset, Tingling sensation, Mouth irritation

SUBSTITUTES FOR GRAMONEX

No substitutes found

Top Physicians

Expert advice FOR GRAMONEX

  • Do not take medicines that contain magnesium, aluminium, calcium, sucralfate, iron, or zinc preparations within 2 to 3 hours of taking nalidixic acid.
  • Do not drink products that contain caffeine while taking nalidixic acid.
  • Continue taking nalidixic acid even if you feel better. Do not stop taking this medication as it may result in relapse of the infection. 
  • Do not drive or operate machinery as nalidixic acid can cause drowsiness, dizziness, or blurred vision. 
  • Do not consume alcohol as nalidixic acid as it may worsen the side effects.
  • Avoid exposure to sun while taking nalidixic acid. Use a sunscreen or wear protective clothing if you must be outside for more than a short time.
  • Seek immediate medical attention if you develop stomach pain or cramps, severe diarrhea, or bloody stools.
  • Consult your doctor if you develop signs of infections as long-term or repeated use of nalidixic acid may cause secondary infections. 
  • Inform your doctor if you are on nalidixic acid treatment as it may affect some tests for urine glucose in patients with diabetes.
  • Use of nalidixic acid is not recommended in children younger than 3 months old or younger than 9 years old with diarrhea or a gastrointestinal infection.
  • You may be monitored with blood tests, kidney and liver function test, if you are on long-term treatment with nalidixic acid.

Frequently asked questions FOR GRAMONEX

Nalidixic Acid

Q.

Is nalidixic acid an antibiotic / quinolone / broad spectrum / fluoroquinolone?
Yes, Nalidixic acid is a broad spectrum quinolone antibiotic

Q.

How does nalidixic acid work/ inhibit bacterial growth /inhibit DNA synthesis?
It works by killing the bacteria that are causing an infection. It does this by entering the bacterial cells and inhibiting a bacterial enzyme called DNA-gyrase

Q.

What does nalidixic acid target?
It stops the production of essential proteins needed by bacteria

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Q.

How does nalidixic acid inhibit DNA synthesis?
Nalidixic acid acts by inhibiting DNA synthesis, probably by interfering with DNA polymerisation.

Metronidazole

Q.

What is metronidazole?
Metronidazole is an antibiotic. It works by killing bacteria and parasites that cause infections in your body.

Q.

What is metronidazole used for?
Metronidazole is active against anaerobic bacteria nd can be used to treat infections of the blood, brain, lung, bones, genital tract, pelvic area, stomach and intestines, gum ulcers and other dental infections, treat infected leg ulcers and pressure sores and to prevent infections after surgery.

Q.

Is metronidazole safe?
Yes, metronidazole is a relatively safe drug if used in prescribed dose and for prescribed duration as advised by your doctor

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Q.

Is metronidazole a pain killer?
Metronidazole is an antibiotic and not pain killer

Q.

Does metronidazole affect birth control?
There is no evidence of metronidazole affecting birth control (contraception) as no interactions have been clinically observed between the two. However, interactions may occur. Please consult your doctor to confirm before taking the two medicines together as you may require a secondary birth control measure while taking metronidazole.

Q.

Is metronidazole an over the counter (OTC) product?
No, metronidazole is not an over the counter (OTC) product. It's a prescription medicine.

Q.

Can metronidazole cause vomiting?
Vomiting has been reported as a side effect with metronidazole. However, the exact incidence is not known. Consult your doctor if vomiting occurs while you are taking metronidazole.

Q.

Can I take metronidazole for urinary tract infections (UTI)?
Metronidazole is indicated for the treatment of infections caused by anaerobic bacteria. It can be indicated for the treatment of urinary tract infections (UTI) only if the underlying cause is anaerobic bacteria. Hence, it is always advisable to consult your doctor who would be able to diagnose your infections and give antibiotics accordingly.

Q.

Can I take metronidazole for yeast (fungal) infection?
Metronidazole is not active against yeast (fungal) infections, hence not recommended to be used for yeast infections.

Q.

Can I take metronidazole for chest infection?
Yes, metronidazole can be taken for chest infections only once the cause of infection is diagnosed and the antibiotics are recommended by your doctor.

Q.

can I take metronidazole for a sinus infection?
Metronidazole can be used for anaerobic sinus infections. Please consult your doctor before taking any antibiotics as the cause of infection must be diagnosed by a doctor before starting the treatment.

Q.

Can I take metronidazole for chlamydia?
Metronidazole is not active against chlamydia. Please consult your doctor before taking any treatment for chlamydia. Antibiotics should be taken only as advised by your doctor.

Q.

Can I take metronidazole for kidney infection?
Metronidazole is indicated for the treatment of infections caused by anaerobic bacteria. It can be indicated for the treatment of kidney infection only if the underlying cause is anaerobic bacteria. Hence, it is always advisable to consult your doctor who would be able to diagnose your infections and give antibiotics accordingly.

Q.

Can I take metronidazole for bronchitis?
Metronidazole is not indicated for the treatment of bronchitis. Consult your doctor if you have symptoms of bronchitis and antibiotics are needed for the same.

Q.

Can I take metronidazole for diarrhea?
Metronidazole is indicated for the treatment of infections caused by anaerobic bacteria. It can be indicated for the treatment of diarrhea only if the underlying cause is anaerobic bacteria. Hence, it is always advisable to consult your doctor who would be able to diagnose your infections and give antibiotics accordingly.

Q.

Can I take metronidazole for a sore throat?
Metronidazole is not indicated for the treatment of a sore throat. It is indicated for the treatment of infections caused by anaerobic bacteria. Hence, it is always advisable to consult your doctor who would be able to diagnose your infections and give antibiotics accordingly.

Q.

Can I take metronidazole for the ear infection?
Metronidazole is indicated for the treatment of infections caused by anaerobic bacteria. So, it can be used for ear infection only if it is caused by anaerobic bacteria. Please consult your doctor in case antibiotics are needed as the antibiotics should be used only once the cause of infection is properly diagnosed.

Q.

Is metronidazole safe in pregnancy?
Metronidazole has been found to be safe in animal studies during pregnancy. However, it should be avoided in pregnancy except if recommended by a doctor as its effects on the human fetus (unborn baby) are not known.

Q.

Is metronidazole steroid?
Metronidazole is not a steroid. It is an antibiotics which acts by killing bacteria.

Q.

Is metronidazole carcinogenic?
There is no evidence of metronidazole showing carcinogenicity in humans. However, it has shown cancer like growth in mouse and rat studies. Please consult your doctor if you have any questions related to this.

Q.

Is metronidazole an antibiotic?
Yes, metronidazole is an antibiotic. It works by killing bacteria and parasites that cause infections in your body.

Q.

Is metronidazole safe while breastfeeding?
It is advised not to breastfeed if you are taking metronidazole as some amounts of metronidazole is secreted in the milk. Please consult your doctor before using any medicine if you are breastfeeding. Your doctor may decide whether you should stop taking metronidazole or stop breastfeeding.

Q.

Is metronidazole bacteriostatic or bactericidal?
Metronidazole is a bactericidal (kills bacteria) agent. It works by killing bacteria and parasites that cause infections in your body.

Q.

Can I take metronidazole without food?
Metronidazole should not be taken without food. It should be taken with food or after food.

Q.

Can I take metronidazole with doxycycline?
Metronidazole can be taken with azithromycin as no interactions have been clinically seen between the two medicines. However, interactions may occur. Please consult your doctor before taking the two medicines together.

Q.

Can I take metronidazole with food?
Metronidazole can be taken with food or after food. It should be swallowed with water, not chewed.

Q.

Can I take metronidazole with milk?
There are no recommendations on if metronidazole should be taken with milk or not. However, it can be taken with food or after food.

Q.

Can I take metronidazole with azithromycin?
Metronidazole can be taken with azithromycin as no interactions have been clinically seen between the two medicines. However, interactions may occur. Please consult your doctor before taking the two medicines together.

Q.

Can I take metronidazole with tramadol?
Metronidazole can be taken with tramadol as no interactions have been clinically seen between the two medicines. However, interactions may occur. Please consult your doctor before taking the two medicines together.

Q.

Can I take metronidazole with alcohol?
Alcohol should be avoided when taking metronidazole. Avoid alcohol for at least 48 hours after metronidazole therapy as it may cause an antabuse reaction.

Q.

can I take metronidazole with paracetamol?
Metronidazole can be taken with paracetamol as no interactions have been clinically seen between the two medicines. However, interactions may occur. Please consult your doctor before taking the two medicines together.

Q.

Can I take metronidazole with fluconazole?
Metronidazole can be taken with fluconazole as no interactions have been clinically seen between the two medicines. However, interactions may occur. Please consult your doctor before taking the two medicines together.

Q.

Can I take metronidazole with gabapentin?
Metronidazole can be taken with gabapentin as no interactions have been clinically seen between the two medicines. However, interactions may occur. Please consult your doctor before taking the two medicines together.

Q.

Does metronidazole delay your period?
Metronidazole is not known to delay monthly period. Consult your doctor if it occurs while taking metronidazole.

Q.

Does metronidazole affect birth control?
No, metronidazole is not shown to affect birth control. It is an antibiotic and works in your body by killing bacteria nd parasites that cause infection.

Q.

Does metronidazole make you fertile?
Metronidazole plays no role in the treatment of infertility. It is an antibiotic and works in your body by killing bacteria nd parasites that cause infection.

Q.

Does metronidazole cause dark urine?
Dark urine has been reported to be an uncommon side effect with metronidazole. If you develop dark urine, talk to your doctor immediately. you may need to stop the medicine.

Q.

Does metronidazole cause constipation?
Yes, metronidazole may cause constipation. Consult your doctor if you have constipation during metronidazole therapy.

Q.

Does metronidazole contain sulfa?
Metronidazole is not a sulfa-containing drug.

Q.

Does metronidazole make you feel tired?
Tiredness has not been reported as a side effect of metronidazole. In case you experience tiredness while taking metronidazole. Please consult your doctor.

Q.

Does metronidazole cause nausea?
There have been reports that metronidazole may cause nausea. However, the exact incidence is not known. Consult your doctor if nausea occurs and persists for a long time when you are taking metronidazole.

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Content on this page was last updated on 08 March, 2017, by Dr. Varun Gupta (MD Pharmacology)