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Last updated on:
20 Aug 2019 | 04:39 PM (IST)
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GM Pio 2mg/500mg/15mg Tablet


Overview

Introduction

GM Pio 2mg/500mg/15mg Tablet is used in the treatment of type 2 diabetes mellitus.

GM Pio 2mg/500mg/15mg Tablet is a combination medicine that can control blood sugar better than a single medication. This medicine should be used along with a proper diet and exercise for best results. It should be taken with food to avoid upset stomach, and it may cause hypoglycemia (low blood sugar level) as a side effect. Monitor your blood sugar level regularly while taking this medicine.

Uses of GM Pio Tablet

GM Pio Tablet side effects

Common
  • Hypoglycemia (low blood sugar level)
  • Nausea
  • Taste change
  • Diarrhea
  • Stomach pain
  • Headache
  • Edema (swelling)
  • Weight gain
  • Blurred vision
  • Bone fracture
  • Respiratory tract infection

How to use GM Pio Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. GM Pio 2mg/500mg/15mg Tablet is to be taken with food.
GM Pio 2mg/500mg/15mg Tablet may cause stomach upset if taken empty stomach.

How GM Pio Tablet works

GM Pio 2mg/500mg/15mg Tablet is a combination of three antidiabetic medicines: Glimepiride, Metformin and Pioglitazone. They work by different mechanisms to provide better control of blood sugar when single or dual therapy is not effective. Glimepiride is a sulfonylurea which works by increasing the amount of insulin released by the pancreas in order to lower the blood glucose. Metformin is a biguanide. It works by lowering glucose production in the liver, delaying glucose absorption from intestines and increasing the body's sensitivity to insulin. Pioglitazone is a thiazolidinedione which further increases insulin sensitivity.

GM Pio Tablet related warnings

Alcohol
UNSAFE
It is unsafe to consume alcohol with GM Pio 2mg/500mg/15mg Tablet Taking pioglitazone with alcohol may affect blood glucose levels in patients with diabetes.
Pregnancy
CONSULT YOUR DOCTOR
GM Pio 2mg/500mg/15mg Tablet may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Lactation
SAFE IF PRESCRIBED
GM Pio 2mg/500mg/15mg Tablet is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.
Monitor the breastfed baby’s blood sugar during treatment with GM Pio 2mg/500mg/15mg Tablet
Driving
CAUTION
Your ability to drive may be affected if your blood sugar is too low or too high. Do not drive if these symptoms occur.
Kidney
CAUTION
GM Pio 2mg/500mg/15mg Tablet should be used with caution in patients with kidney disease. Dose adjustment of GM Pio 2mg/500mg/15mg Tablet may be needed. Please consult your doctor.
Use of GM Pio 2mg/500mg/15mg Tablet is, however, not recommended in patients with severe kidney disease. Regular monitoring of kidney function test is advisable while you are taking this medicine.
Liver
CAUTION
GM Pio 2mg/500mg/15mg Tablet should be used with caution in patients with liver disease. Dose adjustment of GM Pio 2mg/500mg/15mg Tablet may be needed. Please consult your doctor.
Use of GM Pio 2mg/500mg/15mg Tablet is not recommended in patients with severe liver disease.

Alternate Brands

For informational purposes only. Consult a doctor before taking any medicines.
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Expert Advice

  • Take it with food to lower your chance of having an upset stomach.
  • It may cause hypoglycemia (low blood sugar level) when used with other antidiabetic medicines, alcohol or if you delay or miss a meal.
  • Always carry some sugary food or fruit juice with you in case you experience hypoglycemic symptoms such as cold sweats, cool pale skin, tremor, and anxiety.
  • Your doctor may check your liver function regularly. Inform your doctor if you develop symptoms such as abdominal pain, loss of appetite, or yellowing of the eyes or skin (jaundice).

Patient Concerns

Questions Related to GM Pio

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Type 2 diabetes since 10 years. Uncontrolled.Fasting 120. PP 192. Night insulin dose 18 unit mantis + amaryllis m2 forte. Morning- voglibose GM forte 2.+Israel 100 + losakar 25.
Dr. Ashwin Porwal
Diabetes Specialist
kindly check the name of medicinesi need complete history and printed reports of following cbc urine routine and microscopy serum creatinine hba1c fbs ppbs
I HAVE TYPE 2 DIABETES NOW I TAKE A MEDICINE FOR HUMINSULIN 30/70 DAY TIME 35 UNIT NIGHT 25 UNIT GLYCOMET SR 1 GM TWICE A DAY AND CARDACE 5 MG ECOSPIRIN AV 75/20 BUT I HAVE NO CONTROL OF SUGAR AND OTHER I GOT A GASTRIC PROBLEM HOW RECTIFIE THE PROBLEM NOW SUGAR LEVEL AFTER FOOD 256MG PLEASE DO THE NEED FUL. THANKING YOU
Dr. Rajesh Chhabra
Diabetes Specialist
You need to take proper precautions including dos n don't
arrow
Do you have any questions related to GM Pio 2mg/500mg/15mg Tablet?

FAQs

Q. Can I drink alcohol while taking GM Pio?

No, it is not safe to drink alcohol while using GM Pio. Drinking alcohol may lower your blood sugar levels (hypoglycemia). Also, it can increase the chances of lactic acidosis.

Q. What should I inform the doctor before taking GM Pio?

Before taking GM Pio inform your doctor if you have congestive heart failure, kidney problems, liver problems, swelling of the back of the eye. Inform the doctor if you are pregnant, breastfeeding or a premenopausal woman. Let the doctor know if you are taking any prescription and non-prescription medicines, vitamins, and herbal supplements.

Q. Can the use of GM Pio lead to Vitamin B12 deficiency?

Yes, the use of GM Pio can cause vitamin B12 deficiency as it contains metformin in it. On long-term use, it interferes with absorption of vitamin B12 in the stomach.

Q. Can the use of GM Pio cause hypoglycemia?

Yes, the use of GM Pio can cause hypoglycemia (low blood sugar level). Symptoms of hypoglycemia include nausea, headache, irritability, hunger, sweating, dizziness, fast heart rate and feeling anxious or shaky. It happens more often if you miss or delay your meal, drink alcohol, over-exercise or take other antidiabetic medicine along with it. So, regular monitoring of blood sugar level is important. Always carry some sugary item like a candy or chocolate with you.

Q. What are the instructions for the storage and disposal of GM Pio?

Keep this medicine in the container it came in, tightly closed. Store it according to the instructions mentioned on the pack or label. Dispose of the unused medicine. Make sure it is not consumed by pets, children and other people.

Related Products

Disclaimer: 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover all possible side effects, drug interactions or warnings or alerts. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.
References
  1. Glimepiride. North Harrow, Middlesex: Accord Healthcare Limited; 2008 [revised 24 Jul. 2014]. [Accessed 08 Apr. 2019] (online) Available from:External Link
  2. Metformin hydrochloride oral solution. Gloversville, New York: Ranbaxy Pharmaceuticals Inc.; 2003. [Accessed 08 Apr. 2019] (online) Available from:External Link
  3. Pioglitazone hydrochloride. Wooburn Green, High Wycombe: Takeda UK Ltd.; 2000 [revised 13 Sep. 2018]. [Accessed 08 Apr. 2019] (online) Available from:External Link
Manufacturer/Marketer Address
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