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05 Nov 2019 | 10:16 AM (IST)
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Glyson-MF Tablet


Overview

Introduction

Glyson-MF Tablet is a medicine used in the treatment of type 2 diabetes.

Glyson-MF Tablet is a combination of two medicines that effectively controls blood sugar levels when a single medication is not effective. It should be used along with a proper diet and regular exercise for best results. It should be taken with food to avoid side effects like nausea and stomach upset.

Uses of Glyson-MF Tablet

Side effects of Glyson-MF Tablet

Common
  • Hypoglycemia (low blood sugar level)
  • Taste change
  • Nausea
  • Stomach pain
  • Diarrhea
  • Headache
  • Upper respiratory tract infection

How to use Glyson-MF Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Glyson-MF Tablet is to be taken with food.

How Glyson-MF Tablet works

Glyson-MF Tablet is a combination of two antidiabetic medicines: Glipizide and Metformin. Glipizide is a sulfonylurea which works by increasing the amount of insulin released by the pancreas in order to lower the blood glucose. Metformin is a biguanide which works by lowering glucose production in the liver, delaying glucose absorption from intestines and increasing the body's sensitivity to insulin.

Safety Advice

Alcohol
UNSAFE
It is unsafe to consume alcohol with Glyson-MF Tablet.
Pregnancy
CONSULT YOUR DOCTOR
Glyson-MF Tablet may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Breastfeeding
SAFE IF PRESCRIBED
Glyson-MF Tablet is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.
Driving
CAUTION
Your ability to drive may be affected if your blood sugar is too low or too high. Do not drive if these symptoms occur.
Kidney
CAUTION
Glyson-MF Tablet should be used with caution in patients with kidney disease. Dose adjustment of Glyson-MF Tablet may be needed. Please consult your doctor.
Use of Glyson-MF Tablet is, however, not recommended in patients with severe kidney disease. Regular monitoring of kidney function test is advisable while you are taking this medicine.
Liver
CAUTION
Glyson-MF Tablet should be used with caution in patients with liver disease. Dose adjustment of Glyson-MF Tablet may be needed. Please consult your doctor.
Glyson-MF Tablet is generally started with low dose in patients with mild to moderate liver disease and its use is not recommended in patients with severe liver disease.

Alternate Brands

For informational purposes only. Consult a doctor before taking any medicines.
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Quick Tips

  • Monitor your blood sugar level regularly while you are taking this medicine. 
  • It can cause hypoglycemia (low blood sugar level) when used with other antidiabetic medicines, alcohol or if you delay or miss a meal. 
  • Inform your doctor about your diabetes treatment if you are due to have surgery under a general anesthetic.
  • Tell your doctor immediately if you experience any deep or rapid breathing or if you have persistent nausea, vomiting, and stomach pain as Glyson-MF Tablet may cause a rare but serious condition called lactic acidosis, which is an excess of lactic acid in the blood.
  • Your doctor may check your liver function regularly. Inform your doctor if you develop symptoms such as abdominal pain, loss of appetite, or yellowing of the eyes or skin (jaundice).

Patient Concerns

arrow
I have type-2 Diabetes taking trivolib1 And glisen mf 1 Two times a day.before meal.but.my sugar not controlled my.fbs sugar-236 And pp2bs.is 356 Pl,advisr what to do
Dr. Ila Jain Khandelwal
Pathologist
Hi I suggest you should consult your diabetologist or general practitinoer He will see all your previous records and review your treatment
Since 3 years I have Type 2 Diabetes and am presently on 1 tab. of glynase MF .My fasting is 130 and PP goes up to 170-180. I want to lower it further. I have been advised to take 1 tab. of voglibose 0.3 with lunch.Iam unable to walk more than 1 k.m. due to osteoarthritis but I am cycling daily for one hour to compensate. What do I do to control B-G level more effectively?
Dr. Sanjay Bhatt
Diabetes Specialist
It is ok but further maintain your calories intake as per your BMI.CONSULT DIABETIC EDUCATOR
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Do you have any questions related to Glyson-MF Tablet ?

User Feedback


FAQs

Q. What is Glyson-MF?

Glyson-MF is a combination of two medicines: Glipizide and Metformin. This medicine is used in the treatment of type 2 diabetes mellitus (DM). It improves the blood glucose levels in adults when taken along with proper diet and regular exercise. Glipizide lowers the blood glucose levels by increasing the release of insulin from the pancreas. Metformin works by lowering the glucose production in the liver and improving insulin sensitivity. This combination is not indicated for the treatment of type 1 DM.

Q. What are the possible side effects of Glyson-MF?

The use of Glyson-MF is associated with common side effects like hypoglycemia (low blood sugar level), altered taste, nausea, stomach pain, diarrhea, headache and upper respiratory tract infection. Its use can also lead to serious but rare side effects like lactic acidosis. On long-term use, it can also lead to Vitamin B12 deficiency.

Q. Can the use of Glyson-MF cause hypoglycemia?

Yes, the use of Glyson-MF can cause hypoglycemia (low blood sugar level). Symptoms of hypoglycemia include nausea, headache, irritability, hunger, sweating, dizziness, fast heart rate and feeling anxious or shaky. It happens more often if you miss or delay your food, drink alcohol, over-exercise or take other antidiabetic medicine along with it. So, regular monitoring of the blood sugar level is important. Always carry some glucose tablets, honey or fruit juice with you.

Q. Can the use of Glyson-MF cause lactic acidosis?

Yes, the use of Glyson-MF can lead to lactic acidosis. It is a medical emergency which is caused by increased levels of lactic acid in the blood. It is also known as MALA (Metformin associated lactic acidosis). It is a rare side effect associated with the use of metformin and therefore, it is avoided in patients with underlying kidney disease, old age patients or who take large amounts of alcohol. Symptoms of lactic acidosis may include muscle pain or weakness, dizziness, tiredness, feeling of cold in arms and legs, difficulty in breathing, nausea, vomiting, stomach pain or slow heart rate. If you have these symptoms, stop taking Glyson-MF and immediately consult your doctor.

Q. Can the use of Glyson-MF lead to Vitamin B12 deficiency?

Yes, the use of Glyson-MF can cause Vitamin B12 deficiency on long-term use. It interferes with absorption of Vitamin B12 in the stomach. If untreated, it may cause anemia and nerve problems and the patient can feel a tingling sensation and numbness in the hands and feet, weakness, urinary problems, change in mental status and difficulty in maintaining balance (ataxia). To avoid such problems, some researchers suggest an intake of Vitamin B12 from outside sources at least once every year.

Q. Are there any specific conditions in which Glyson-MF should not to be taken?

The use of Glyson-MF should be avoided in patients with known allergy to any of the components or excipients of this medicine. It should also be avoided in patients with moderate to severe kidney disease and in patients with underlying metabolic acidosis including diabetic ketoacidosis.

Q. Is it safe to take alcohol while I am also taking Glyson-MF?

No, it is not safe to take Glyson-MF along with alcohol, as it may lower your low blood sugar levels (hypoglycemia) and can increase the chances of lactic acidosis.

Q. What are the instructions for storage and disposal of Glyson-MF?

Keep this medicine in the container or the pack it came in, tightly closed. Store it according to the instructions mentioned on the pack or label. Dispose of the unused medicine. Make sure it is not consumed by pets, children and other people.

Related Products

Disclaimer: 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover all possible side effects, drug interactions or warnings or alerts. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.
References
  1. Glipizide+metformin HCl. Princeton, New Jersey: Bristol-Myers Squibb Company. [Accessed 29 Jan. 2019] (online) Available from:External Link
  2. Drugs.com. Glipizide+Metformin. [Accessed 08 Apr. 2019] (online) Available from:External Link
  3. Glipizide and Metformin Hydrochloride. Ahmedabad, India: Cadila Healthcare Ltd; 2016. [Accessed 08 Apr. 2019] (online) Available from:External Link
Manufacturer/Marketer Address
Unison Pharmaceuticals Pvt. Ltd., "UNISON HOUSE" Near Prernatirth Derasar, Near Ratnadeep-II, Satellite, Jodhpur, Ahmedabad-380 015, GUJARAT, INDIA.
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