Medicine Overview of Gliotem Capsule
Gliotem 20 mg Capsule is used in the treatment of brain tumor
Side Effects of Gliotem are Rash, Headache, Dizziness, Convulsion, Coordination disorder, Insomnia (difficulty in sleeping), Vomiting, Weakness, Nausea, Loss of appetite, Hair loss, Fatigue, Fever, Diarrhoea, Memory loss, Constipation, Hemiparesis (weakness on one side of the body), Viral infection.
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Gliotem 20 mg Capsule is to be taken empty stomach.
Gliotem 20 mg Capsule is an anti-cancer medication. It enters the brain tissues and works by damaging the genetic material (DNA and RNA) of the cancer cells. This stops their growth and multiplication.
In Depth Information on Gliotem Capsule
- Swallow full tablets on an empty stomach, one hour before your meal.
- Avoid being near people who are sick or have infections. Consult your doctor if you develop symptoms of opportunistic infections (such as Pneumocystis jirovecii pneumonia) and reactivation of infections (such as hepatitis B virus) Using temozolomide may increase your risk of developing certain types of bone marrow cancer. Be aware about your specific risk.
- You may be given medication to prevent nausea or other side effects while you are receiving temozolomide.
- Your blood will be tested frequently during treatment to monitor the side effects of temozolomide on your blood cells as you may have a small risk of other changes in blood cells, including leukemia.
- Avoid activities that may increase your risk of bleeding or injury. Use extra care to prevent bleeding while shaving or brushing your teeth.
- Do not drink alcohol while taking temozolomide.
- Do not drive or operate machinery while using temozolomide as it may make you tired or sleepy.
- Both male and female patients should take effective contraceptive precautions during and after 6 months of treatment. Male patients should seek advice on conservation of sperm prior to treatment as temozolomide treatment may cause infertility.
Gliotem Capsule related warnings
Interaction with alcohol is unknown. Please consult your doctor.
WEIGH RISKS VS BENEFITS
Gliotem 20 mg Capsule is unsafe to use during pregnancy.
There is positive evidence of human fetal risk, but the benefits from use in pregnant women may be acceptable despite the risk, for example in life-threatening situations. Please consult your doctor.
Gliotem 20 mg Capsule is unsafe to use during lactation.
Data suggests that the drug may cause toxicity to the baby, or the mother is suffering from a condition in which breastfeeding is not advisable.
Gliotem 20 mg Capsule may make you feel dizzy, sleepy, tired, or decrease alertness. If this happens, do not drive.
Gliotem 20 mg Capsule is probably safe to use in patients with kidney disease. Limited data available suggests that dose adjustment of Gliotem 20 mg Capsule may not be needed in these patients. Please consult your doctor.
Cautious use is advised in patients with severe kidney disease while they are taking Gliotem 20 mg Capsule.
Gliotem 20 mg Capsule should be used with caution in patients with severe liver disease. Dose adjustment of Gliotem 20 mg Capsule may be needed. Please consult your doctor.
Limited information is available on the use of Gliotem 20 mg Capsule in these patients. No dose adjustment is recommended in patients with mild to moderate liver disease.
If you miss a dose of Gliotem 20 mg Capsule, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
Frequently asked questions about Gliotem Capsule
Q. What is Gliotem used for/ what does Gliotem treat/ Is Gliotem chemotherapy/ is Gliotem cytotoxic/ is Gliotem a radiosensitizer?
Gliotem is an anti-cancer (antineoplastic or cytotoxic) chemotherapy drug. It is used to treat specific types of brain tumor. It is a radiosensitizer
Q. Is Gliotem effective/ does Gliotem work?
Gliotem is effective and works for patients if taken at recommended dosage and duration as recommended by the doctor
Q. How is Gliotem given/administered/ metabolized/ how long does Gliotem stay in the body?
Gliotem is given as a capsule and is taken by mouth. It should be administered in the fasting state, at least one hour before meal. It is rapidly metabolized at physiologic pH to the active monomethyl triazenoimidazole carboxamide (MTIC). The half-life (t1/2) in plasma is approximately 1.8 hours
Q. How does Gliotem cross the blood-brain barrier?
Gliotem because of its small size and lipophilic properties is able to cross the blood-brain barrier rapidly and is present in the cerebrospinal fluid
Q. Does Gliotem cause hair loss?
Hair loss is a side effect of using Gliotem. Always follow doctor's advice regarding its use
Q. Is Gliotem FDA approved?
Gliotem is a FDA approved drug.
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