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Gliben DM Plus 5 mg/500 mg Tablet

Prescription Required

Primary uses of Gliben DM Plus 5 mg/500 mg Tablet

Potentiallyunsafewith
Alcohol
MRP
23.81
₹2.38/Tablet
10 tablets in 1 strip
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Medicine Overview of Gliben DM Plus Tablet

Uses of Gliben DM Plus Tablet

Gliben DM Plus 5 mg/500 mg Tablet is used in the treatment of type 2 diabetes.

Gliben DM Plus Tablet side effects

Common

Side Effects of Gliben DM Plus are Hypoglycemia (low blood sugar level), Taste change, Nausea, Diarrhoea, Stomach pain, Headache, Upper respiratory tract infection.

How to use Gliben DM Plus Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Gliben DM Plus 5 mg/500 mg Tablet is to be taken with food.
This medicine may cause stomach upset if taken empty stomach.

How Gliben DM Plus Tablet works

Gliben DM Plus 5 mg/500 mg Tablet is a combination of two antidiabetic medicines: Glibenclamide and Metformin. Glibenclamide is a sulfonylurea which works by increasing the amount of insulin released by the pancreas in order to lower the blood glucose. Metformin is a biguanide which works by lowering glucose production in the liver, delaying glucose absorption from intestines and increasing the body's sensitivity to insulin.

In Depth Information on Gliben DM Plus Tablet

Expert advice for Gliben DM Plus Tablet

  • You have been prescribed this combination medicine as it can control blood sugar better than metformin alone.
  • You should continue to exercise regularly, eat a healthy diet, and take your other diabetes medicines along with Gliben DM Plus 5 mg/500 mg Tablet.
  • Take it with food to lower your chance of having an upset stomach.
  • Monitor your blood sugar level regularly while you are taking this medicine. 
  • Inform your doctor about your diabetes treatment if you are due to have surgery under a general anaesthetic.
  • It can cause hypoglycemia (low blood sugar level) when used with other antidiabetic medicines, alcohol or if you delay or miss a meal. 
  • Tell your doctor immediately if you experience any deep or rapid breathing, or persistent nausea, vomiting, and stomach pain as Gliben DM Plus 5 mg/500 mg Tablet may cause a rare but serious condition called lactic acidosis, which is an excess of lactic acid in the blood.
  • Your doctor may check your liver function regularly. Inform your doctor if you develop symptoms such as abdominal pain, loss of appetite, or yellowing of the eyes or skin (jaundice).
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Gliben DM Plus Tablet related warnings
Special precautions for Gliben DM Plus Tablet
Alcohol
CAUTION
Taking metformin with alcohol can cause lactic acidosis and you may experience malaise, respiratory distress, slow or irregular heartbeat, sleepiness, stomach upset, or other unusual symptoms.
Pregnancy
PROBABLY SAFE
Gliben DM Plus 5 mg/500 mg Tablet is probably safe to use during pregnancy.
Animal studies have shown low or no adverse effect on the foetus, however, there are limited human studies. Please consult your doctor.
Lactation
Gliben DM Plus 5 mg/500 mg Tablet is probably safe to use during lactation. Limited human data suggests that the drug does not represent a significant risk to the baby.
Driving
Your ability to drive may be affected if your blood sugar is low or high. If this happens, do not drive.
Kidney
UNSAFE
Gliben DM Plus 5 mg/500 mg Tablet is probably unsafe to use in patients with kidney disease and should be avoided. Please consult your doctor.
Liver
CAUTION
Gliben DM Plus 5 mg/500 mg Tablet should be used with caution in patients with liver disease. Dose adjustment of Gliben DM Plus 5 mg/500 mg Tablet may be needed. Please consult your doctor.
Gliben DM Plus 5 mg/500 mg Tablet is generally started with low dose in patients with mild to moderate liver disease and its use is not recommended in patients with severe liver disease.

Patient Concerns

Frequently asked questions about Gliben DM Plus Tablet

Frequently asked questions about Gliben DM Plus Tablet

Q. What is Gliben dm plus?
Gliben dm plus is a combination of two medicines: Glibenclamide and Metformin. This medicine is used in the treatment of type 2 diabetes mellitus (DM) along with diet and exercise to improve blood glucose levels in adults. Glibenclamide lowers the blood glucose levels by increasing the release of insulin from the pancreas. Metformin works by lowering the glucose production in the liver and improving insulin sensitivity. This combination is not indicated for the treatment of Type 1 DM.
Q. What is type 2 diabetes?
Type-2 diabetes, which is the most common form is a condition when the body is not able to make enough insulin, and the insulin produced by the body does not work well. When this happens, the level of glucose rises in the blood that leads to serious medical problems. Symptoms of high blood sugar include frequent urination, increased thirst, and increased hunger. Diabetes, if not treated properly, can cause long-term complications like neuropathy (nerve damage), nephropathy (kidney damage), eye damage (retinopathy), foot problems and also develop higher risk of heart diseases.
Q. What are the possible side effects of Gliben dm plus?
The use of Gliben dm plus is associated with common side effects like hypoglycemia (low blood sugar level), altered taste, nausea, stomach pain, diarrhea, headache and upper respiratory tract infection. Its use can also lead to serious, but rare side effects like lactic acidosis. On long-term use, it can also lead to Vitamin B12 deficiency.
Q. Can the use of Gliben dm plus cause hypoglycemia?
Yes, the use of Gliben dm plus can cause hypoglycemia (low blood sugar level). Symptoms of hypoglycemia include nausea, headache, irritability, hunger, sweating, dizziness, fast heart rate and feeling anxious or shaky. It happens more often if you miss or delay your food, drink alcohol, do more than routine exercise or take other antidiabetic medicine along with. So, regular monitoring of blood sugar level is important. Always keep a quick source of sugar like glucose tablets, honey or fruit juice with you.
Q. Can the use of Gliben dm plus cause lactic acidosis?
Yes, the use of Glipenclamide+Metformin can lead to lactic acidosis. It is a medical emergency which is caused by increased levels of lactic acid in the blood. It is also known as MALA (Metformin associated lactic acidosis). It is a rare side effect associated with the use of metformin and therefore, it is contraindicated in patients with underlying kidney disease, old age patients or who take large amounts of alcohol. Symptoms of lactic acidosis may include muscle pain or weakness, dizziness, tiredness, feeling of cold in arms and legs, difficulty in breathing, nausea, vomiting, stomach pain or slow heart rate. If you have these symptoms, stop taking Glipizide+Metformin and immediately consult your doctor
Q. Can the use of Gliben dm plus lead to Vitamin B12 deficiency?
Yes, the use of Gliben dm plus can cause vitamin B12 deficiency on long-term use as it interferes with absorption of vitamin B12 in the stomach. If untreated, it may cause anemia and nerve problems and the patient can have tingling sensation and numbness in hands and feet, weakness, urinary problems, change in mental status and difficulty in making balance (ataxia). To avoid such problems, some researchers suggest an intake of vitamin B12 from outside at least once every year.
Q. Are there any specific conditions in which Gliben dm plus should not to be taken?
The use of Gliben dm plus should be avoided in patients with known allergy to any of the component or excipients of this medicine, in patients with moderate to severe kidney disease and in patients with underlying metabolic acidosis including diabetic ketoacidosis.
Q. Is it safe to take alcohol while I am also taking Gliben dm plus?
No, it is not safe to take Gliben dm plus along with alcohol, as it may lower your low blood sugar levels (hypoglycemia) and can increase the chances of lactic acidosis.
Q. Does Gliben dm plus expire?
Yes, Gliben dm plus does expire. The expiry date is written on the pack of the medicine and it refers to the last day of the month mentioned. Do not use Gliben dm plus after the expiry date.
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