Gibtulio-SM 25/1000 Tablet ER
Prescription RequiredProduct introduction
Gibtulio-SM 25/1000 Tablet ER is a medicine used to treat type 2 diabetes mellitus. It works by lowering sugar production and improving insulin action. It also removes excess glucose, helping maintain better blood sugar control.
Gibtulio-SM 25/1000 Tablet ER should be taken exactly as prescribed. It can be taken with or without food. Regular dosing is important to keep blood sugar under control. Do not skip doses or stop without medical advice, as this may cause uncontrolled diabetes. If a dose is missed, take it as soon as remembered, but do not double the dose.
The most common side effects include hypoglycaemia, headache, thirst, constipation, increased urination, and urinary tract infection. Some patients may experience low blood sugar when taken with insulin or sulfonylureas. Rarely, dehydration, excessive thirst, or ketoacidosis may occur.
Gibtulio-SM 25/1000 Tablet ER should not be used in patients with severe kidney impairment, end-stage renal disease, or dialysis. It is contraindicated in people with metabolic acidosis or diabetic ketoacidosis. Caution is required in those with a history of frequent urinary or genital infections, dehydration, heart failure, or low blood pressure. It should not be used during pregnancy or breastfeeding unless clearly needed. Regular monitoring of kidney function, blood sugar, and hydration status is advised.
Uses of Gibtulio-SM Tablet ER
Benefits of Gibtulio-SM Tablet ER
In Treatment of Type 2 diabetes mellitus
Type 2 diabetes mellitus is a condition where the body cannot manage blood sugar effectively, leading to persistently high glucose levels. Gibtulio-SM 25/1000 Tablet ER helps lower and control blood sugar through complementary actions that improve how the body handles glucose. It helps to maintain stable blood sugar control, reducing the risk of complications and supporting overall health in people with type 2 diabetes.
Side effects of Gibtulio-SM Tablet ER
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Gibtulio-SM
- Hypoglycemia (low blood glucose level)
- Headache
- Increased thirst
- Constipation
- Frequent urge to urinate
- Urinary tract infection
How to use Gibtulio-SM Tablet ER
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Gibtulio-SM 25/1000 Tablet ER may be taken with or without food, but it is better to take it at a fixed time.
How Gibtulio-SM Tablet ER works
Gibtulio-SM 25/1000 Tablet ER is a combination of sitagliptin, metformin, and empagliflozin. Metformin decreases glucose production in the liver and improves the body’s response to insulin. Sitagliptin increases insulin release and lowers glucose production after meals by improving natural hormone activity. Empagliflozin helps remove excess glucose through urine by blocking its reabsorption in the kidneys. When combined, these actions complement each other, reducing sugar production, improving insulin action, and promoting glucose elimination. This multi-target approach provides stronger, more balanced blood sugar control and helps lower the risk of long-term complications in type 2 diabetes.
Safety advice
Alcohol
UNSAFE
It is unsafe to consume alcohol with Gibtulio-SM 25/1000 Tablet ER.
Pregnancy
CONSULT YOUR DOCTOR
Gibtulio-SM 25/1000 Tablet ER may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Breast feeding
CONSULT YOUR DOCTOR
Gibtulio-SM 25/1000 Tablet ER is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
Driving
CAUTION
Your ability to drive may be affected if your blood sugar is too low or too high. Do not drive if these symptoms occur.
Kidney
CAUTION
Gibtulio-SM 25/1000 Tablet ER should be used with caution in patients with severe kidney disease. Dose adjustment of Gibtulio-SM 25/1000 Tablet ER may be needed. Please consult your doctor.
Liver
CAUTION
Gibtulio-SM 25/1000 Tablet ER should be used with caution in patients with liver disease. Dose adjustment of Gibtulio-SM 25/1000 Tablet ER may be needed. Please consult your doctor.
What if you forget to take Gibtulio-SM Tablet ER?
If you miss a dose of Gibtulio-SM 25/1000 Tablet ER, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
All substitutes
For informational purposes only. Consult a doctor before taking any medicines.
No substitutes found for this medicine
Quick tips
- Stay well hydrated to avoid dehydration and kidney-related problems.
- Maintain good personal hygiene to reduce the risk of urinary or genital infections.
- Monitor blood sugar levels regularly and attend follow-up checkups.
- Inform your doctor immediately if you experience symptoms like extreme thirst, nausea, vomiting, or rapid breathing (possible ketoacidosis).
Fact Box
Habit Forming
No
Therapeutic Class
ANTI DIABETIC
Patient concerns
FAQs
What is Gibtulio-SM 25/1000 Tablet ER used for?
It is used to manage type 2 diabetes mellitus by helping control blood sugar levels when diet and exercise alone are not enough.
What side effects should I watch for?
Common side effects include urinary or genital infections, frequent urination, or diarrhea. Rarely, serious conditions like ketoacidosis or dehydration may occur.
Can I use Gibtulio-SM 25/1000 Tablet ER with insulin?
Yes, but combining with insulin or sulfonylureas may increase the risk of low blood sugar. Your doctor may adjust doses to reduce this risk.
Is Gibtulio-SM 25/1000 Tablet ER safe during pregnancy or breastfeeding?
It is not recommended during pregnancy or breastfeeding unless clearly needed. Always consult your doctor before use.
Want to share the information?
Disclaimer:
Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.References
- Empagliflozin, sitagliptin, and metformin hydrochloride [Product Information]. Valsad, Gujarat: Torrent Pharmaceuticals Ltd. [Accessed 27 Aug. 2025] (online) Available from:
Marketer details
Name: Lupin Ltd
Address: 3rd floor Kalpataru Inspire, Off. W E Highway, Santacruz (East), Mumbai 400 055. India
Country of origin: India
Expires on or after: July, 2027
A licensed vendor partner from your nearest location will deliver Gibtulio-SM 25/1000 Tablet ER. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's ℞ and the availability of this medicine.
Phone Number: 0124-4166666
Address: 5th Floor Tower - B of the Presidency Building, 46/4 Mehrauli Gurgaon Road, Sector 14, Gurugram, Haryana-122001, India
Expires on or after: July, 2027
A licensed vendor partner from your nearest location will deliver Gibtulio-SM 25/1000 Tablet ER. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's ℞ and the availability of this medicine.
In case of any issues, contact us
Email ID: [email protected]Phone Number: 0124-4166666
Address: 5th Floor Tower - B of the Presidency Building, 46/4 Mehrauli Gurgaon Road, Sector 14, Gurugram, Haryana-122001, India
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MRP₹210 10% OFF
₹189
Inclusive of all taxes
10.0 tablet er in 1 strip
New GST benefit included in this MRP, may differ from label
Get by Friday, 24 October
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