Overview
Uses and benefits
Side effects
How to use
How drug works
Safety advice
Missed dose
All substitutes
Quick tips
Fact box
Patient concerns
FAQs

Author Details

Written By

Dr. Syeda Aafia

MBA, BDS

Reviewed By

Dr. Mekhala Chandra

MD, MBBS

Last updated

21 Sep 2025 | 05:45 PM (IST)

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Home>Gastro-SL>gastro-sl capsule

Gastro-SL Capsule

Prescription Required

Marketer

SSK Pharma

SALT COMPOSITION

Levosulpiride (75mg) + Esomeprazole (40mg)

Storage

Store below 30°C

View available alternative with same salt composition

Click here to view all substitutes

Product introduction

Gastro-SL Capsule is a prescription medicine used in the treatment of gastroesophageal reflux disease (acid reflux). It works by relieving the symptoms such as heartburn, stomach pain, or irritation. It also neutralizes the acid production in the stomach to prevent discomfort.

Gastro-SL Capsule is taken without food in a dose and duration as advised by the doctor. The dose you are given will depend on your condition and how you respond to the medicine. You should keep taking this medicine for as long as your doctor recommends. If you stop treatment too early your symptoms may come back and your condition may worsen. Let your healthcare team know about all other medications you are taking as some may affect, or be affected by this medicine.

The most common side effects include diarrhea, nausea, vomiting, stomach pain, flatulence, constipation, and headache. Most of these are temporary and usually resolve with time. Contact your doctor straight away if you are at all concerned about any side effects. To overcome constipation, you should add fibre-rich foods in your diet and stay hydrated. It may also cause sleepiness, so do not drive or do anything that requires mental focus until you know how this medicine affects you. Avoid drinking alcohol while taking this medicine as it can worsen your sleepiness. Lifestyle modifications like having cold milk and avoiding hot tea, coffee, spicy food or chocolate can help you to get better results.

Before taking this medicine, you should tell your doctor if you are pregnant, planning pregnancy or breastfeeding. You should also tell your doctor if you have liver or kidney diseases so that your doctor can prescribe a suitable dose for you.

Uses of Gastro-SL Capsule

Treatment of Gastroesophageal reflux disease (Acid reflux)

Benefits of Gastro-SL Capsule

In Treatment of Gastroesophageal reflux disease (Acid reflux)

Gastroesophageal reflux disease (GERD) is a chronic (long-term) condition in which there is an excess production of acid in the stomach. Gastro-SL Capsule reduces the amount of acid your stomach makes and relieves the pain associated with heartburn and acid reflux. You should take it exactly as it is prescribed for it to be effective.
Some simple lifestyle changes can help reduce the symptoms of GERD. Think about what foods trigger heartburn and try to avoid them; eat smaller, more frequent meals; try to lose weight if you are overweight and try to find ways to relax. Do not eat within 3-4 hours of going to bed.

Side effects of Gastro-SL Capsule

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Gastro-SL

Nausea
Vomiting
Diarrhea
Constipation
Upset stomach
Stomach pain
Headache
Flatulence
Sleepiness
Fundic gland polyps

How to use Gastro-SL Capsule

Take this medicine in the dose and duration as advised by your doctor. Gastro-SL Capsule is to be taken empty stomach.

How Gastro-SL Capsule works

Gastro-SL Capsule is a combination of two medicines: Levosulpiride and Esomeprazole.

Safety advice

Alcohol

UNSAFE

It is unsafe to consume alcohol with Gastro-SL Capsule.

Pregnancy

CONSULT YOUR DOCTOR

Gastro-SL Capsule may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.

Breast feeding

CONSULT YOUR DOCTOR

Information regarding the use of Gastro-SL Capsule during breastfeeding is not available. Please consult your doctor.

Driving

UNSAFE

Gastro-SL Capsule may cause side effects which could affect your ability to drive.
Gastro-SL Capsule may cause drowsiness, numbness, or dyskinesias, therefore they should be advised to avoid driving and operations requiring supervision.

Kidney

CONSULT YOUR DOCTOR

There is limited information available on the use of Gastro-SL Capsule in patients with kidney disease. Please consult your doctor.
However, limited data suggest a cautious use of this medicine in these patients.

Liver

CAUTION

Gastro-SL Capsule should be used with caution in patients with severe liver disease. Dose adjustment of Gastro-SL Capsule may be needed. Please consult your doctor.

What if you forget to take Gastro-SL Capsule?

If you miss a dose of Gastro-SL Capsule, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

All substitutes

For informational purposes only. Consult a doctor before taking any medicines.

Gastro-SL Capsule

₹9.29/Capsule

Somifiz L Capsule

Mankind Pharma Ltd

₹21.7/capsule

134% costlier

Esoper L Capsule

Signova Pharma Pvt Ltd

₹16.9/capsule

82% costlier

Espra L 75mg/40mg Capsule

Zydus Cadila

₹17.9/capsule

93% costlier

Somaday-L Capsule

Kayra Innopharm Pvt Ltd

₹26.7/capsule

187% costlier

Es Omepraz L 75mg/40mg Capsule

Alkem Laboratories Ltd

₹23.5/capsule

153% costlier

Quick tips

It is a well-tolerated medicine and provides relief for a long time.
Take it one hour before the meal, preferably in the morning.
Inform your doctor if you get watery diarrhea, fever, or stomach pain that does not go away.
Do not consume alcohol while taking Gastro-SL Capsule as it can increase the risk of stomach damage.
Long-term use may cause weak or broken bones. Take adequate intake of dietary calcium and vitamin D or their supplements. Do not take Gastro-SL Capsule for longer than prescribed.

Fact Box

Habit Forming

Therapeutic Class

GASTRO INTESTINAL

Patient concerns

Gastro Esophagel Reflux Disorder

Dr. Ankit Soni

Homeopathy

Continue with the present medicines. Also avoid lying down immediately after lunch or dinner. If you have to lie down then use a higher pillow. This will in easing the reflux of contents from the stomach.

Please give me a diet chart for a patient who face gastro-esphageal reflux disease.

Shikha Mishra

Dietetics/Nutrition

eat 6-7 meals per day, which consist fruits, nuts, buttermilk,egg, homecooked food. Drink 3-4 litters of water limit your sugar consumption to 2 spoon per day. Be active whole day for personalized diet chart write to me on [email protected] do minimum 45 min exercise everyday like yoga, cardio or weights

I am having ulcers in my mouth due to which i cant eat food secondly whenever i eat i feel burning in my chest . suffering from such condition since a month my doctor told me that i m deficit of vitamin . but he didnt say which vitamin . so i want to know if he is right

Dr. Sfurti Mann

Internal Medicine

You have gastritis and Gastro esophageal reflux. Can take sompraz-IT OD before breakfast n syp digene thrice daily 2tsf.

Heartburn Mental disorder Depression Frequent persistent heartburn Gastroesophageal reflux disease Irritable bowel syndrome Indigestion Back flow of acid from stomach Difficulty in swallowing Inflammation of esophagus Excess acid secretion by stomach Intestinal or stomach ulcers

Dr. Sunil Sekhri

Diabetology

You need to be examined in clinic to reach a diagnosis and then appropriate medicine can be prescribed

What are the instructions for storage and disposal of Gastro-SL Capsule?

Keep this medicine in the container or the pack it came in, tightly closed. Store it according to the instructions mentioned on the pack or label. Dispose of the unused medicine. Make sure it is not consumed by pets, children and other people.

What is the best time to take Gastro-SL Capsule?

Take Gastro-SL Capsule exactly as directed by your doctor. It is best to take one capsule daily on an empty stomach.

What are the contraindications associated with the use of Gastro-SL Capsule?

The use of Gastro-SL Capsule should be avoided in patients with known allergy to any of the components or excipients of this medicine.

Can the use of Gastro-SL Capsule cause dizziness?

Yes, the use of Gastro-SL Capsule can cause dizziness (feeling faint, weak, unsteady or lightheaded) in some patients. If you feel dizzy or lightheaded, it is better to rest for some time and resume once you feel better.

Does the use of Gastro-SL Capsule lead to increased risk of fractures?

Several studies in adults suggest that treatment with Gastro-SL Capsule may be associated with an increased risk for osteoporosis-related fractures of the hip, wrist or spine. The risk of fracture was increased in patients who received high dose. High dose can mean multiple daily doses, and long-term therapy (a year or longer).

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Disclaimer:

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

References

ScienceDirect. Levosulpiride. [Accessed 12 Apr. 2019] (online) Available from:
Esomeprazole DR and Levosulpiride ER [Patient Information Sheet]. Haridwar, Uttarakhand: Torrent Pharmaceuticals Ltd.; 2020. [Accessed 28th Sept. 2023] (online) Available from: