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Frulac Sachet

Written By Dr. Anuj Saini, MMST, MBBS
Reviewed By Dr. Rajeev Sharma, MBA, MBBS
Last updated on 25 Nov 2025 | 05:18 PM (IST)
Frulac Sachet is used to treat resistant hypertension, chronic cardiac failure, and hepatic cirrhosis. It is commonly used when fluid buildup (edema) or high blood pressure cannot be controlled by a single medicine. It helps remove excess salt and water from the body, reducing swelling and fluid overload.
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Frulac Sachet image
Frulac Sachet image

Product introduction

Take Frulac Sachet exactly as prescribed by your doctor, preferably with breakfast and/or lunch along with a full glass of water. Avoid taking it in the evening to prevent nighttime urination. For the best results, take the medicine at the same time every day and do not stop on your own, even if you start feeling better.


Continue to follow your doctor’s advice about dietary salt and fluid intake. In conditions like hypertension or heart failure, your doctor may recommend limiting salt, avoiding alcohol, and maintaining a healthy weight. Regular follow-up visits are important, as your doctor may monitor blood pressure, kidney function, and electrolyte levels (especially potassium and sodium).


The most common side effects of Frulac Sachet include electrolyte disturbances, hyponatremia (low sodium level in blood), dehydration, and hypovolemia (decreased blood volume). Because this medicine increases urine output, you may feel thirsty or need to urinate more often. To reduce side effects, drink adequate water, avoid excessive sweating or dehydration, and do not use salt substitutes containing potassium unless your doctor advises it.


Do not take Frulac Sachet if you have kidney failure, severe liver disease (hepatic encephalopathy), high potassium levels, or low sodium levels, or if you are dehydrated. It is also contraindicated in pregnancy and breastfeeding due to potential harm to the baby. Avoid alcohol and other medicines that may lower blood pressure or increase potassium levels, such as ACE inhibitors, potassium supplements, or certain painkillers (NSAIDs). Be cautious while driving or operating machinery, as dizziness or drowsiness may occur, especially at the start of treatment.

Benefits of Frulac Sachet

Treatment of Resistant Hypertension (high blood pressure)
Frulac Sachet helps in the management of resistant hypertension (high blood pressure) that does not respond to standard diuretic therapy. It helps remove excess salt and water from the body and prevents potassium loss. This helps lower blood pressure more effectively in patients with secondary hyperaldosteronism, a condition where excess aldosterone causes fluid buildup and makes blood pressure harder to control.
Treatment of Chronic Heart Failure
In chronic congestive cardiac failure, the heart struggles to pump blood effectively, leading to fluid buildup in the lungs and body. Frulac Sachet helps remove this excess fluid, reducing swelling (edema), breathlessness, and strain on the heart. It is especially useful in resistant edema associated with secondary hyperaldosteronism, where single diuretic therapy is not sufficient.
Treatment of Liver cirrhosis with edema
In hepatic cirrhosis, impaired liver function often causes fluid accumulation in the abdomen (ascites) and swelling due to secondary hyperaldosteronism. Frulac Sachet helps reduce this fluid buildup by removing excess salt and water while maintaining potassium balance and preventing further electrolyte disturbances. It is specifically indicated for resistant edema in patients with hepatic cirrhosis when conventional diuretic therapy alone is inadequate.

Side effects of Frulac Sachet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Frulac
  • Electrolyte imbalance
  • Volume depletion

How to use Frulac Sachet

Take this medicine in the dose and duration as advised by your doctor. Check the label for directions before use. Empty the granules in a glass of water/milk, stir it and consume immediately. Frulac Sachet should be taken with or after food.
Avoid Frulac Sachet with dietary sodium.

How Frulac Sachet works

Frulac Sachet contains two medicines: furosemide and spironolactone, which act on different parts of the kidney to remove excess fluid. Furosemide is a short-acting loop diuretic that helps the kidneys eliminate sodium, chloride, and water through urine, thereby reducing fluid overload and blood pressure. Spironolactone is a long-acting aldosterone antagonist that promotes the excretion of sodium and water while conserving potassium, helping maintain electrolyte balance and preventing potassium loss during treatment.

Quick tips

  • Frulac Sachet helps remove excess water from your body.
  • Take it in the morning with breakfast to avoid getting up at night to urinate.
  • It may cause dizziness or sleepiness. Don't drive or do anything requiring concentration until you know how it affects you.
  • To lower the chance of feeling dizzy or passing out, rise slowly if you have been sitting or lying down.
  • It may cause excessive urine production, dehydration, and low electrolyte levels. Notify your doctor if you experience dizziness, tiredness, or muscle weakness that doesn't go away.
  • Your doctor may regularly monitor your blood pressure, kidney function, and the level of salts such as potassium and sodium in your blood while you're taking this medication.

Safety advice

Alcohol

Alcohol

CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with Frulac Sachet. Please consult your doctor.
Pregnancy

Pregnancy

UNSAFE
Frulac Sachet is highly unsafe during pregnancy. It can cause serious harm to the unborn baby, including birth defects and pregnancy loss. Do not use this medicine if you are pregnant or planning to become pregnant.
Breast feeding

Breast feeding

UNSAFE
Frulac Sachet is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.
Driving

Driving

UNSAFE
Frulac Sachet may decrease alertness, affect your vision, or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
Kidney

Kidney

UNSAFE
Frulac Sachet is unsafe to use in patients with kidney disease and should be avoided.
Liver

Liver

CAUTION
Frulac Sachet should be used with caution in patients with severe liver disease. Dose adjustment may be needed.

Frequently asked questions

The use of Frulac Sachet should be avoided in patients with hypersensitivity to furosemide, sulfonylureas or spironolactone or any other ingredient of the product. The use of this medicine should also be avoided in patients with anuria, acute renal insufficiency, hepatic coma and pre-coma, low blood pressure (hypotension), cardiac arrhythmias, patients taking aminoglycosides or cephalosporins, kidney dysfunction due to drugs which cause renal damage, patients with high potassium levels (hyperkalemia), Addison's disease and in children with moderate to severe renal impairment.
Frulac Sachet is a fixed-dose combination of furosemide (a loop diuretic) and spironolactone (an antagonist of aldosterone). Both are diuretics and they help to remove excess fluid from the body. The use of this combination is advised in patients with resistant hypertension, congestive heart failure (heart failure leading to fluid accumulation in the lung and rest of the body), and liver cirrhosis with fluid retention (edema).
Yes, Frulac Sachet is safe for most of the patients. However, in some patients it may cause common side effects like dizziness, dehydration, decreased sodium level in blood, breast enlargement in males, decreased magnesium level in blood, decreased calcium level in blood, increased blood uric acid. Inform your doctor if you experience any persistent problem while taking this medicine.
Yes, the use of Frulac Sachet can cause dizziness (feeling faint, weak, unsteady or lightheaded) in some patients. If you feel dizzy or lightheaded, it is better to rest for some time and resume once you feel better. Do not drive or use any machines.
Yes, Frulac Sachet can cause gout. Frulac Sachet contains furosemide which can increase the blood uric acid levels by increasing its absorption from the kidneys. Increased uric acid levels can cause a gout attack. Inform your doctor if you have hyperuricemia (excess of uric acid in blood) or a history of gout before taking this medicine. Use of Frulac Sachet should be avoided in patients with gout.

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Habit Forming

No

Therapeutic Class

CARDIAC
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Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

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Name: Ecstasy Biotech Pvt Ltd
Address: 1459-A IST FLOORRANI BAGH NEW DELHI New Delhi DL 110034 IN , - , .

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Country of origin: India
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