Flu-Stim Injection
Prescription RequiredProduct introduction
Flu-Stim Injection is used in the treatment of blood cancer called chronic lymphocytic leukemia (CLL). It may be used to treat other conditions, as determined by the doctor. It is sometimes used with certain other medicines as part of combination chemotherapy.
Flu-Stim Injection is given as infusion into veins under the supervision of doctor. Your doctor will decide what dose is necessary and how often you need to take it. This will depend on what you are being treated for and may change from time to time. You should take it exactly as your doctor has advised. Taking it in the wrong way or taking too much can cause very serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to.
The most common side effects of this medicine include nausea, vomiting, diarrhea, headache, weakness, fever, and cough. This medicine may reduce the number of blood cells (decrease white blood cells and red blood cells) in your blood, thereby, increasing the susceptibility to infections. Regular blood tests are required to check your blood cells along with heart, liver, and blood uric acid levels.
Before taking it, tell your doctor if you have heart disease, liver, or kidney problems or are taking any medicines to treat infections. Many other medicines can affect, or be affected by, this medicine so let your doctor know all medications you are using. This medicine is not recommended during pregnancy or while breastfeeding. The use of effective contraception by both males and females during treatment is important to avoid pregnancy.
Uses of Flu-Stim Injection
Benefits of Flu-Stim Injection
In Blood cancer (Chronic lymphocytic leukemia)
Blood cancer, also called leukemia, is a cancer of the blood-forming tissues, that decreases the body's ability to fight infection. Flu-Stim Injection kills or stops the growth of cancer cells and also prevents the multiplication of cancer cells. It is an effective medicine but you should discuss the side effects and benefits of this medicine with your doctor. Let your doctor know if any of the side effects bothers you.
Side effects of Flu-Stim Injection
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Flu-Stim
- Increased risk of infection
- Vomiting
- Weakness
- Nausea
- Fatigue
- Fever
- Decreased blood cells (red cells, white cells, and platelets)
- Diarrhea
- Cough
How to use Flu-Stim Injection
Your doctor or nurse will give you this medicine. Kindly do not self administer.
How Flu-Stim Injection works
Flu-Stim Injection is an anticancer medication. It works by interfering with the growth of genetic material (DNA and RNA) of the cancer cells in blood. This slows the growth of cancer cells and eventually kills them.
Safety advice
Alcohol
CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with Flu-Stim Injection. Please consult your doctor.
Pregnancy
CONSULT YOUR DOCTOR
Flu-Stim Injection is not recommended during pregnancy as there is positive evidence of fetal risk based on animal studies. However, it may still be prescribed by a doctor in situations where the benefits outweigh the risks.
Breast feeding
UNSAFE
Flu-Stim Injection is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.
Driving
UNSAFE
Flu-Stim Injection may decrease alertness, affect your vision, or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
Some people get tired, feel weak, have disturbed vision, become confused, or agitated or have seizures while they are treated with Flu-Stim Injection and this may affect your ability to drive.
Some people get tired, feel weak, have disturbed vision, become confused, or agitated or have seizures while they are treated with Flu-Stim Injection and this may affect your ability to drive.
Kidney
CAUTION
Flu-Stim Injection should be used with caution in patients with severe kidney disease. Dose adjustment may be needed.
Use of Flu-Stim Injection is not recommended in patients with severe kidney disease.
Use of Flu-Stim Injection is not recommended in patients with severe kidney disease.
Liver
CONSULT YOUR DOCTOR
There is limited data available on the use of Flu-Stim Injection in patients with liver disease.
What if you forget to take Flu-Stim Injection?
If you miss a dose of Flu-Stim Injection, please consult your doctor.
All substitutes
For informational purposes only. Consult a doctor before taking any medicines.
No substitutes found for this medicine
Quick tips
- Use a reliable contraceptive method to prevent pregnancy while you are taking this medicine.
- Inform your doctor immediately if you notice any signs of infection such as fever, sore throat, rash or severe diarrhea.
Fact Box
Chemical Class
Purine nucleosides
Habit Forming
No
Therapeutic Class
ANTI NEOPLASTICS
Action Class
Antimetabolites
Interaction with drugs
Taking Flu-Stim with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
Do not consume Fludarabine from 1 day before until 1 day after taking Molgramostim. Please consult your doctor.
Concurrent use may cause a decrease in the ability of the bone marr
Do not consume Fludarabine from 1 day before until 1 day after taking Sargramostim. Please consult your doctor.
Concurrent use may cause a decrease in the ability of the bone marr
Do not consume Fludarabine from 14 days before until 24 days after taking Pegfilgrastim. Please consult your doctor.
Concurrent use may cause a decrease in the ability of the bone
Do not consume Lenograstim from 24 hours before until 24 hours after undergoing cytotoxic chemotherapy.
Concurrent use may cause a decrease in the ability of the bone marrow to pr
Do not consume Natalizumab with Fludarabine.
Concomitant use may increase the risk of opportunistic infections.
Patient concerns
FAQs
What is Flu-Stim Injection used to treat?
Flu-Stim Injection is a chemotherapy medicine used to treat certain types of blood cancers, primarily B-cell chronic lymphocytic leukemia (CLL). It may also be used for other blood cancers such as non-Hodgkin’s lymphoma and acute myeloid leukemia.<br>
How often will I need to get Flu-Stim Injection?
A typical treatment schedule with Flu-Stim Injection involves receiving the medicine once a day for five consecutive days. This five-day treatment cycle is usually repeated every 28 days. Your doctor will determine the exact number of cycles you need.<br>
My doctor said Flu-Stim Injection is for “refractory” CLL. What does that mean?
If your doctor prescribed Flu-Stim Injection for refractory CLL, this means that your chronic lymphocytic leukemia has either not responded to previous standard treatments or it has come back after you have been treated with at least one other type of chemotherapy, such as an alkylating agent.<br>
Will I need to have a lot of blood tests during my Flu-Stim Injection treatment?
Yes. You will need to have frequent blood tests. Flu-Stim Injection can significantly affect your bone marrow, which can lead to low levels of red blood cells, white blood cells, and platelets. Your doctor will monitor your blood counts closely to manage these effects.<br>
Why is my doctor so concerned about infections while I am on Flu-Stim Injection?
Flu-Stim Injection works by targeting and destroying cancer cells, but it also strongly suppresses your immune system, which can last for a long time. This makes you much more vulnerable to serious infections, so it is very important to take precautions and report any signs of infection to your doctor right away.<br>
I need a blood transfusion during Flu-Stim Injection treatment. Is there anything special I need to know?
Yes. This is very important. If you need a blood transfusion while you are being treated with Flu-Stim Injection, the blood products you receive must be irradiated (treated with radiation) first. This is to prevent a rare, but very serious complication called transfusion-associated graft-versus-host disease.<br>
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Disclaimer:
Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.References
- Chabner BA, Bertino J, Cleary J, et al. Cytotoxic Agents. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. pp. 1702-703.
- Chu E, Sartorelli AC. Cancer Chemotherapy. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. p. 948.
- Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 555-56.
- Fludarabine phosphate. Bedford, Ohio: Ben Venue Laboratories. [Accessed 27 Mar. 2017] (online) Available from:
- Central Drugs Standard Control Organisation (CDSCO). [Accessed 27 Mar. 2019] (online) Available from:
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Name: Zydus Cadila
Address: Zydus Tower, Satellite Cross Roads,Ahmedabad – 380015 Gujarat, India.
Country of origin: India
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