Febuvel 80mg Tablet

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Leeford Healthcare Ltd

Composition for Febuvel 80mg Tablet

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Primarily used for

Potentiallyunsafewith
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Alcohol
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Pregnancy
140
₹14.0/Tablet
10 tablets in 1 strip
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Medicine Overview of Febuvel Tablet

uses

Uses of Febuvel Tablet

Febuvel 80mg Tablet is used in the treatment of gout
It is a long-term treatment to lower blood uric acid levels and to prevent gout attacks.
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Side effects of Febuvel Tablet

Common

Skin rash, Headache, Nausea, Edema, Increased liver enzymes, Diarrhoea.

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How to use Febuvel Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. It can be taken with or without food, but it is better to take Febuvel 80mg Tablet at a fixed time.

How Febuvel Tablet works

Febuvel 80mg tablet blocks the enzyme xanthine oxidase involved in the synthesis of uric acid and hence lowers the blood uric acid levels.

In Depth Information on Febuvel Tablet

Expert advice for Febuvel Tablet

  • Febuvel is not a painkiller and it may take a few days to weeks before it starts working. You would need to take additional medicines to relieve your pain and inflammation during this time.
  • You may experience an increase in gouty attacks for first few weeks or months of taking Febuvel. However, you must continue to take your medicine during these attacks.
  • Do not stop taking Febuvel at once or without talking to your doctor as this may make your gout worse.
  • Drink lots of water or fluids while taking Febuvel to decrease the risk of kidney stone formation.
  • Get your liver function tests done before you start taking this medicine and whenever asked by your doctor as Febuvel can affect your liver.
  • Get your blood uric acid levels checked at regular intervals.
  • Febuvel can make you feel drowsy. Avoid driving, use of machinery, or any activity that requires you to be alert.
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Warnings
Special precautions for Febuvel 80mg Tablet
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Alcohol
CAUTION
Taking alcohol can increase your uric acid levels and hence aggravate gout.
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Pregnancy
WEIGH RISKS VS BENEFITS
Febuvel 80mg Tablet may be unsafe to use during pregnancy.

Animal studies have shown adverse effects on the foetus, however, there are limited human studies. The benefits from use in pregnant women may be acceptable despite the risk. Please consult your doctor.
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Lactation
CAUTION
Febuvel 80mg Tablet should be used with caution during lacta
tion. Breast feeding should be held until the treatment of the mother is completed and the drug is eliminated from her body.
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Driving
Do not drive unless you are feeling well.

Febuvel 80mg Tablet may cause dizziness, sleepiness, blurred vision, numbness or tingling sensation. This may affect your driving ability.
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Kidney
Febuvel 80mg Tablet should be used with caution in patients with severe kidney disease. Dose adjustment of Febuvel 80mg Tablet may be needed. Please consult your doctor.

Limited information is available for use of Febuvel 80mg Tablet in patients with severe kidney disease.
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Liver
UNSAFE
Febuvel 80mg Tablet is probably unsafe to use in patients with liver disease and should be avoided. Please consult your doctor.

No dose adjustment is needed for patients with the mild to moderate liver disease.Not advisable in patients with the severe liver disease.
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Missed Dosageuses

If you miss a dose of Febuxostat, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

Patient Concerns

Frequently asked questions for Febuvel 80mg Tablet

Frequently asked questions for Febuxostat

Q. Can I take Febuvel with rosuvastatin?
Rosuvastatin can be taken with Febuvel. Rosuvastatin is used to lower bad cholesterol and Febuvel is used to lower uric acid levels in patients with gout. Many patients of high cholesterol levels also have high uric acid levels. There are no human studies available on this interaction. However, animal research shows that when given together, Febuvel can increase the blood levels of Rosuvastatin causing a higher risk of its side effects like muscle pain and muscle damage. So, a dose adjustment of Rosuvastatin may be needed when given along with Febuvel.
Febuvel is not known to cause frequent urination. However, if you experience any such symptom while using the drug, consult your doctor.
Gout is a type of arthritis in which uric acid levels are very high in the blood and they get deposited in the joints causing swelling, redness and sudden pain in these joints. Febuvel works by inhibiting the enzyme xanthine oxidase involved in the synthesis of uric acid and hence decreases the level of uric acid in the blood.
No, Febuvel is not a steroid. It is a xanthine oxidase inhibitor and decreases the serum uric acid levels.
Febuvel is not indicated for the treatment of hypertriglyceridemia. Conclusive evidence showing the drug lowering triglyceride levels is lacking.
After oral intake, the peak plasma concentration of Febuvel is achieved between 1 to 1.5 hours. However, it may take a few days to weeks to show its effect and you can experience gout attacks during this time. Continue to take your medicine during this time as with continuous use these attacks would decrease.
Q. How is Febuvel different from allopurinol?
Both allopurinol and Febuvel work in a similar way by lowering uric acid levels. However, as compared to allopurinol, Febuvel is seen to be more effective and faster in its action. Also, in patients taking allopurinol, a dose adjustment is needed if the patient has mild, moderate or severe renal failure while in the case of Febuvel a dose adjustment may be needed only in patients with severe renal failure.
Febuvel is not an over the counter product. It is a prescription medicine and is available as per the doctor's advice.
Studies have shown that Febuvel is safe for long-term use. However, it should be taken only for the duration as per the doctor's advice.
Febuvel is not indicated for the treatment of heart failure. However, high uric acid levels is a risk factor for cardiovascular diseases and the benefit of urate-lowering therapy for cardiac diseases is being explored.
Febuvel is not indicated for the treatment of chronic kidney disease. However, it can be safely used in patients with mild to moderate renal failure for lowering uric acid levels. Safety of the drug in severe renal failure is not established.
Febuvel is not used for the treatment of cancer. However, patients with malignant cancer when given anti-cancer drugs, experience a serious condition known as tumor lysis syndrome characterized by increased potassium, phosphate and uric acid levels in the blood due to the killing of cancer cells and this can lead to acute kidney injury, cardiac arrhythmia, and seizures. Febuvel helps in this condition by lowering the uric acid levels and preventing further complications.
Q. Can I take Febuvel with allopurinol?
Both Febuvel and allopurinol are uric acid lowering agents and work in a similar way. So, using both the two medicines together may not be very beneficial and can increase the risk of side effects. However, there have been studies where Febuvel when used with allopurinol in patients with refractory gout, was quite effective in providing relief. So, a combined use would be best decided by your treating doctor depending on your condition.
Febuvel is not indicated in the treatment of kidney stones. However, some studies show that high renal uric acid excretion may precipitate the formation of calcium stones in the kidney and hence, suggest Febuvel may have a role in the reduction of stone formation.
Q. Can I take Febuvel with colchicine?
Febuvel can be taken with colchicine. In the initial few days of starting Febuvel, patients may experience an increase in gout attacks because of the movement of uric acid and colchicine and painkillers are given to these patients for the relief of pain and inflammation.
Q. Can I take Febuvel with azathioprine?
Febuvel should not be taken with azathioprine. Taking both the medicines together will increase the levels of azathioprine and can cause toxicity.
Febuvel can generally be taken safely together with antibiotics. However, interactions can occur. Talk to your doctor about the right antibiotic therapy for your condition while you are also taking Febuvel.
Use of Febuvel is contraindicated in patients being treated with azathioprine, mercaptopurine, theophylline, and in patients who develop hypersensitivity to the drug.
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