


Espazine 1mg Injection
Written By Dr. Sakshi Jain, MS, BDS,
Reviewed By Dr. Rajeev Sharma, MBA, MBBS,
Last updated on 25 Nov 2025 | 03:05 PM (IST)
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General Information



Product introduction
Espazine 1mg Injection is given as an injection under the supervision of a healthcare professional and should not be self-administered. Take it at the same time each day as this helps to maintain a consistent level of medicine in the body. Take this medicine in the dose and duration as advised by your doctor and if you have missed a dose, take it as soon as you remember it. Do not skip any doses and finish the full course of treatment even if you feel better. This medication mustn't be stopped suddenly without talking to your doctor as it may worsen your symptoms.
Some common side effects of this injection include dry mouth, abnormality of voluntary movements, urinary retention, constipation, and muscle rigidity. Initially, this medicine may cause a sudden drop in blood pressure when you change positions, rise slowly if you have been sitting or lying down. It may also cause dizziness and sleepiness, do not drive or do anything that requires mental focus until you know how this medicine affects you. This medicine can lead to weight gain, have a healthy balanced diet, and exercise regularly. You may also notice some injection site reactions such as pain, redness, or swelling. However, these are temporary and usually resolve on their own. Please consult your doctor in case these do not subside or bother you.
Before taking it, inform your doctor if you are suffering from thyroid or kidney problems, epilepsy, Parkinson’s disease, glaucoma, or any heart problems. You should not take this medicine if you are under the influence of alcohol or any sleep-inducing, cough, and/ or allergy medication. This medicine can also lead to weight gain, eat a healthy balanced diet, avoid snacking with high-calorie food, and exercise regularly.
Uses of Espazine Injection
Benefits of Espazine Injection
Schizophrenia is a serious mental health condition that affects how a person thinks, feels, and behaves, often leading to symptoms like hallucinations, delusions, and disorganized thinking. Espazine 1mg Injection helps manage these symptoms by restoring the balance of certain natural substances in the brain. This can improve clarity of thought, reduce false beliefs or perceptions, and support more stable emotional and behavioral responses.
Side effects of Espazine Injection
- Injection site reactions (pain, swelling, redness)
How to use Espazine Injection
How Espazine Injection works
Quick tips
- You have been prescribed Espazine 1mg Injection for the treatment of schizophrenia.
- It may cause less weight gain as compared to other similar medicines.
- Use caution while driving or doing anything that requires concentration as Espazine 1mg Injection can cause dizziness and sleepiness.
- To lower the chance of feeling dizzy or passing out, rise slowly if you have been sitting or lying down.
- Avoid drinking alcohol while taking this medicine as it can cause increased sedation.
- Inform your doctor if you experience abnormal movements, particularly of the face, lips, jaw and tongue, while taking this medicine.
- It may increase your blood sugar and cholesterol level. Eat healthy, exercise regularly and monitor your blood levels regularly.
- Don't stop taking Espazine 1mg Injection without talking to your doctor first as it may cause worsening of symptoms.
- You have been prescribed Espazine 1mg Injection for the treatment of schizophrenia.
- It may cause less weight gain as compared to other similar medicines.
- Take it at bedtime to avoid feeling sleepy during the day.
- Use caution while driving or doing anything that requires concentration as Espazine 1mg Injection can cause dizziness and sleepiness.
- To lower the chance of feeling dizzy or passing out, rise slowly if you have been sitting or lying down.
- Avoid drinking alcohol while taking this medicine as it can cause increased sedation.
- Inform your doctor if you experience abnormal movements, particularly of the face, lips, jaw and tongue, while taking this medicine.
- It may increase your blood sugar and cholesterol level. Eat healthy, exercise regularly and monitor your blood levels regularly.
- Don't stop taking Espazine 1mg Injection without talking to your doctor first as it may cause worsening of symptoms.
Safety advice

Alcohol

Pregnancy

Breast feeding

Driving
Espazine 1mg Injection make u feel dizzy, drowsy or can cause blurred vision. This may affect your driving ability.

Kidney

Liver
However, the use of Espazine 1mg Injection is not considered safe in patients with liver disease as per the available data.
Interaction with drugs
Iopamidol (Injection Route)
Iohexol (Injection Route)
Moxifloxacin (Oral Route)
Moxifloxacin (Injection Route)
Lithium carbonate (Oral Route)
Fact Box
Chemical Class
Habit Forming
Therapeutic Class
Action Class
References
- Stahl SM, editor. Trifluoperazine. In: Stahl's Essential Pschopharmacology: Prescriber's Guide. 5th ed. New York, New York: Cambridge University Press; 2014. pp. 691-95.
- Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. p. 1404.
- Drugs and Lactation Database (LactMed) [Internet]. Bethesda (MD): National Library of Medicine (US); 2006. Trifluoperazine. [Updated 2018 Oct 31]. [Accessed 20 Feb. 2020] (online) Available from:




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