Espazine 1mg Injection is used in the treatment of schizophrenia. It alters the thoughts and elevates the mood, improving the person’s ability to think, feel, and behave.
Espazine 1mg Injection is given as an injection under the supervision of a healthcare professional and should not be self-administered. Take it at the same time each day as this helps to maintain a consistent level of medicine in the body. Take this medicine in the dose and duration as advised by your doctor and if you have missed a dose, take it as soon as you remember it. Do not skip any doses and finish the full course of treatment even if you feel better. This medication mustn't be stopped suddenly without talking to your doctor as it may worsen your symptoms.
Some common side effects of this injection include dry mouth, abnormality of voluntary movements, urinary retention, constipation, and muscle rigidity. Initially, this medicine may cause a sudden drop in blood pressure when you change positions, rise slowly if you have been sitting or lying down. It may also cause dizziness and sleepiness, do not drive or do anything that requires mental focus until you know how this medicine affects you. This medicine can lead to weight gain, have a healthy balanced diet, and exercise regularly. You may also notice some injection site reactions such as pain, redness, or swelling. However, these are temporary and usually resolve on their own. Please consult your doctor in case these do not subside or bother you.
Before taking it, inform your doctor if you are suffering from thyroid or kidney problems, epilepsy, Parkinson’s disease, glaucoma, or any heart problems. You should not take this medicine if you are under the influence of alcohol or any sleep-inducing, cough, and/ or allergy medication. This medicine can also lead to weight gain, eat a healthy balanced diet, avoid snacking with high-calorie food, and exercise regularly.
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Espazine
Injection site reactions (pain, swelling, redness)
How to use Espazine Injection
Your doctor or nurse will give you this medicine. Kindly do not self administer.
How Espazine Injection works
Espazine 1mg Injection is a typical antipsychotic. It works by blocking the action of dopamine, a chemical messenger in the brain that affects thoughts and mood.
Safety advice
Alcohol
UNSAFE
Espazine 1mg Injection may cause excessive drowsiness with alcohol.
Pregnancy
CONSULT YOUR DOCTOR
Espazine 1mg Injection may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Breast feeding
CONSULT YOUR DOCTOR
Espazine 1mg Injection is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
Driving
UNSAFE
Espazine 1mg Injection may cause side effects which could affect your ability to drive. Espazine 1mg Injection make u feel dizzy, drowsy or can cause blurred vision. This may affect your driving ability.
Kidney
CONSULT YOUR DOCTOR
There is limited information available on the use of Espazine 1mg Injection in patients with kidney disease. Please consult your doctor.
Liver
CONSULT YOUR DOCTOR
There is limited information available on the use of Espazine 1mg Injection in patients with liver disease. Please consult your doctor. However, the use of Espazine 1mg Injection is not considered safe in patients with liver disease as per the available data.
All substitutes
For informational purposes only. Consult a doctor before taking any medicines.
No substitutes found for this medicine
Quick tips
You have been prescribed Espazine 1mg Injection for the treatment of schizophrenia.
It may cause less weight gain as compared to other similar medicines.
Use caution while driving or doing anything that requires concentration as Espazine 1mg Injection can cause dizziness and sleepiness.
To lower the chance of feeling dizzy or passing out, rise slowly if you have been sitting or lying down.
Avoid drinking alcohol while taking this medicine as it can cause increased sedation.
Inform your doctor if you experience abnormal movements, particularly of the face, lips, jaw and tongue, while taking this medicine.
It may increase your blood sugar and cholesterol level. Eat healthy, exercise regularly and monitor your blood levels regularly.
Don't stop taking Espazine 1mg Injection without talking to your doctor first as it may cause worsening of symptoms.
You have been prescribed Espazine 1mg Injection for the treatment of schizophrenia.
It may cause less weight gain as compared to other similar medicines.
Take it at bedtime to avoid feeling sleepy during the day.
Use caution while driving or doing anything that requires concentration as Espazine 1mg Injection can cause dizziness and sleepiness.
To lower the chance of feeling dizzy or passing out, rise slowly if you have been sitting or lying down.
Avoid drinking alcohol while taking this medicine as it can cause increased sedation.
Inform your doctor if you experience abnormal movements, particularly of the face, lips, jaw and tongue, while taking this medicine.
It may increase your blood sugar and cholesterol level. Eat healthy, exercise regularly and monitor your blood levels regularly.
Don't stop taking Espazine 1mg Injection without talking to your doctor first as it may cause worsening of symptoms.
Fact Box
Chemical Class
Phenothiazine Derivative
Habit Forming
No
Therapeutic Class
NEURO CNS
Action Class
Typical Antipsychotics
Interaction with drugs
Taking Espazine with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
Do not consume Moxifloxacin with Trifluoperazine. If concurrent use is essential, watch out for symptoms such as muscle spasms, tremors, tiredness, nausea, reduced appetite, palpit... More
Do not consume Moxifloxacin with Trifluoperazine. If concurrent use is essential, watch out for symptoms such as muscle spasms, tremors, tiredness, nausea, reduced appetite, palpit... More
If concurrent use is essential, watch out for symptoms such as double vision, weakness, dizziness, impaired coordination, or confusion and consult your doctor if you experience the... More
My father is taking espazine plus (BD) along with Kemadrin 5 mg (BD) but right now espazine plus is available at most of the market. Can i purchase any substitute of that medicine? If yes, then which one? Sorry Espazine plus is not available at any stores!
Dr. Jyoti Kapoor Madan
Psychiatry
Trifluperazine and trihexyphenidyl are available at pharmacies. Please take proper prescription for medicines, just because someone was prescribed medicines once, doesn't mean one should continue it without regular follow up.
Lack of concentration, lack of motivation, lack of determination doctor prescribed me Trifluoperazine Tablets (espazine) 1 mg is it alright to take if we have adhd , and at what time we should take it ?
Dr. Mehtab Baig
Orthopaedic Physiotherapy
It may be right medicine, but consult a Physician plz, he can better advise
She had a psyco problem 25 yrs before since then she take Espazine plus daily 001 dose, without that she fells dis comfort. Will it give side effect, if so any eqealant or new drug please
Dr. Venkatraju Kalidindi
Psychiatry
Dear 1mg user, medicines gives quick relief and has side effects too so consult your doctor and see how to reduce dose and control totally, later you can take counselling that really helps you.
contacts your neurophysician or neuro psychtrist or some of meditation or exercises contact my clinic because of,this type of patient differ from others
Schizophrenia is a chronic problem caused by Neuro chemical disturbance in brain. It is characterised by fear, odd experiences and distorted thought pattern. Treatment is with antipsychotic medicines which may need to continue throughout life. Coping with a mental disorder as serious as schizophrenia can be challenging, both for the person with the condition and for friends and family. Here are some ways to cope: 1. Learn about schizophrenia. Education about the disorder can help motivate the person with the disease to stick to the treatment plan. Education can help friends and family understand the disorder and be more compassionate with the person who has it. 2. Join a support group. Support groups for people with schizophrenia can help them reach out to others facing similar challenges. Support groups may also help family and friends cope. 3. Stay focused on goals. Managing schizophrenia is an ongoing process. Keeping treatment goals in mind can help the person with schizophrenia stay motivated. Help your loved one remember to take responsibility for managing the illness and working toward goals. 4. Ask about social services assistance. These services may be able to assist with affordable counselling services, job placements and other daily activities. 5. Learn relaxation and stress management. The person with schizophrenia and loved ones may benefit from stress-reduction techniques such as meditation, yoga or tai chi. Please see a psychiatrist for further guidance.
Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.
References
Stahl SM, editor. Trifluoperazine. In: Stahl's Essential Pschopharmacology: Prescriber's Guide. 5th ed. New York, New York: Cambridge University Press; 2014. pp. 691-95.
Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. p. 1404.
Drugs and Lactation Database (LactMed) [Internet]. Bethesda (MD): National Library of Medicine (US); 2006. Trifluoperazine. [Updated 2018 Oct 31]. [Accessed 20 Feb. 2020] (online) Available from:
