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Epithra 100 Injection

Prescription Required
SALT COMPOSITION
Storage
Store in a refrigerator (2 - 8°C). Do not freeze.
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Product introduction

Epithra 100 Injection is used in the treatment of various types of cancers of blood, breast, stomach, lung, ovaries and soft tissues. It also helps to prevent the recurrence of bladder cancer after surgery.

It is given as a drip or infusion vein with extreme caution by a qualified medical professional. It can be used alone, or sometimes given together with certain other medicines as part of combination chemotherapy. Your doctor will decide what dose is necessary and how often you need to take it. This will depend on what you are being treated for and may change from time to time. You should take it exactly as your doctor has advised. Taking it in the wrong way or taking too much can cause very serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to. It makes contraceptive pills less effective, so it advised to both male and female to use reliable contraception during the treatment.

The most common side effects of this medicine include nausea, low blood platelets, hair loss, absence of menstrual periods, fever and rash. It is known to reduce the number of blood cells in your blood thereby, increasing the susceptibility to infections. Infections can sometimes be life threatening. Regular blood tests are required to monitor your blood cells along with kidney, liver and heart function during treatment with this medicine.

Before taking this medicine, tell your doctor if you have liver disease, or have heart problem. Your doctor should also know about all other medicines you are taking as many of these may make this medicine less effective or change the way it works. Inform your doctor if you are pregnant or breastfeeding.

Uses of Epithra Injection

Benefits of Epithra Injection

In Cancer

Epithra 100 Injection helps to treat certain kinds of cancer. It may be used alone or in combination with other medicines to treat cancer in various parts of the body. Epithra 100 Injection kills or stops the growth of cancer cells and also prevents the multiplication of cancer cells. It is a potent and very toxic medicine and you should discuss the risks and benefits with your doctor. You should avoid drinking alcohol while having this treatment and drink plenty of water to stay hydrated.

Side effects of Epithra Injection

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Epithra

  • Low blood platelets
  • Nausea
  • Hair loss
  • Absence of menstrual periods
  • Fever
  • Anemia (low number of red blood cells)
  • Diarrhea
  • Weight loss
  • Decreased white blood cell count (neutrophils)
  • Hot flashes
  • Gastrointestinal inflammation
  • Rash
  • Low energy
  • Eye disorder

How to use Epithra Injection

Your doctor or nurse will give you this medicine. Kindly do not self administer.

How Epithra Injection works

Epithra 100 Injection is an anti-cancer medication. It works by suppressing the activity of an enzyme (topoisomerase II) involved in DNA multiplication of the breast cancer cells. It also forms harmful chemicals (free radicals) which cause DNA damage. This slows the growth of breast cancer cells and eventually kills them.

Safety advice

Alcohol
UNSAFE
It is unsafe to consume alcohol with Epithra 100 Injection.
Pregnancy
CONSULT YOUR DOCTOR
Epithra 100 Injection is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.
Breast feeding
UNSAFE
Epithra 100 Injection is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.
Driving
UNSAFE
Epithra 100 Injection may cause side effects which could affect your ability to drive.
Epithra 100 Injection may cause episodes of nausea and vomiting, which can temporarily lead to an impairment of the ability to drive.
Kidney
SAFE IF PRESCRIBED
Epithra 100 Injection is probably safe to use in patients with kidney disease. Limited data available suggests that dose adjustment of Epithra 100 Injection may not be needed in these patients. Please consult your doctor.
Lower doses may be considered in patients with serum creatinine > 5 mg/dL.
Liver
CAUTION
Epithra 100 Injection should be used with caution in patients with liver disease. Dose adjustment of Epithra 100 Injection may be needed. Please consult your doctor.
Use of Epithra 100 Injection is not recommended in patients with severe liver disease.

All substitutes

For informational purposes only. Consult a doctor before taking any medicines.
Epithra 100 Injection
₹2049/Injection
Rubilon 100mg Injection
Celon Laboratories Ltd
₹3315.31/injection
59% costlier
Alrubicin 100 Injection
Alkem Laboratories Ltd
₹2314/injection
11% costlier
Zuvicin 100mg Injection
Zuventus Healthcare Ltd
₹2335/injection
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Epitaz 100mg Injection
Intas Pharmaceuticals Ltd
₹2890.49/injection
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Epicure 100mg Injection
Emcure Pharmaceuticals Ltd
₹2229/injection
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Quick tips

  • Epithra 100 Injection is used alone or in combination with other medicines for the treatment of various types of cancers.
  • It is given through a drip into a vein (intravenous infusion) by a doctor or nurse.
  • It may make you feel tired or sleepy.  Do not drive or do anything that requires mental focus until you know how it affects you.
  • Use a reliable contraceptive method to prevent pregnancy while you are taking this medicine and for 6 months after stopping treatment.
  • Your doctor may get regular blood tests done to monitor your blood cells, liver, and heart function during treatment with this medicine.
  • Inform your doctor immediately if you notice any signs of infection such as fever, sore throat or rash.

Fact Box

Chemical Class
Anthracycline Derivative
Habit Forming
No
Therapeutic Class
ANTI NEOPLASTICS
Action Class
Alkaloids-cytotoxic agents

Interaction with drugs

Taking Epithra with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
Concomitant use may affect heart rhythm. Do not consume Epirubicin with Domperidone.
Concomitant use may affect heart rhythm. Do not consume Epirubicin with Domperidone.
Concomitant use may affect heart rhythm. Do not consume Epirubicin with Domperidone.
Concomitant use may affect heart rhythm. Do not consume Epirubicin with Domperidone.
Concomitant use may affect heart rhythm. Do not consume Epirubicin with Domperidone.

Patient concerns

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Sir my brother have skin cancer can you do something for save his life ??
Dr. Sanjay Singh Rai
Medical Oncology and Hematology
Treatment of cancer depends on whether it is localized or metastatic cancer
How we can find out parient is CA and which report we can do for know the patient is CA
Dr. Sanjay Singh Rai
Medical Oncology and Hematology
Thr is no single test for cancerWhich cancer ur looking for
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FAQs

Is Epithra 100 Injection a vesicant (agent that causes tissue blistering and damage)?

Yes, Epithra 100 Injection is a vesicant; it may cause tissue blistering if it leaks out of the vein.

How effective is Epithra 100 Injection?

Epithra 100 Injection is effective in the treatment of various cancers including cancer of the breast, ovary, stomach, lung, bowel or rectum, malignant lymphomas (a type of blood cancer of infection-fighting cells of the blood) such as Hodgkin's disease and non-Hodgkin's lymphoma, leukemia (blood cancer), multiple myeloma (a type of blood cancer of infection-fighting cells of the blood). It may be used in bladder cancers and to prevent reoccurrence of bladder cancer after surgery. It effectively slows or stops the growth of cancer cells in the body.

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Disclaimer:

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

References

  1. Chabner BA, Bertino J, Cleary J, et al. Cytotoxic Agents. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. p. 1715.
  2. Chu E, Sartorelli AC. Cancer Chemotherapy. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. p. 952.
  3. Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 478-79.
  4. Epirubicin hydrochloride. Wedel, Germany: Medac GmbH; 2008 [revised Jun. 2016]. [Accessed 26 Mar. 2019] (online) Available from:External Link
  5. Central Drugs Standard Control Organisation (CDSCO). [Accessed 27 Mar. 2019] (online) Available from:External Link

Marketer details

Name: Glenmark Pharmaceuticals Ltd
Address: Glenmark Pharmaceuticals Limited, B/2, Mahalaxmi Chambers, 22, Bhulabhai Desai Road, Mumbai – 400 026.
Country of origin: India
Expires on or after: March, 2025

A licensed vendor partner from your nearest location will deliver Epithra 100 Injection. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's ℞ and the availability of this medicine.

In case of any issues, contact us

Email ID: [email protected]
Phone Number: 0124-4166666
Address: 5th Floor Tower - B of the Presidency Building, 46/4 Mehrauli Gurgaon Road, Sector 14, Gurugram, Haryana-122001, India

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1.0 Injection in 1 vial
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