Epalpex-M SR Tablet is a medicine used in the treatment of diabetic nerve disease. It protect the nerve fibers from damage and promotes regeneration of nerve cells. It is used along with other blood sugar lowering medications in order to prevent further nerve injury.
Epalpex-M SR Tablet may be taken with or without food, but you should try to take it at the same time every day. The dose will be decided by your doctor. Do not stop taking it without asking your doctor. If you do, your blood sugar levels may increase and put you at risk of serious complications like kidney damage and blindness. This medicine is only part of a treatment program that should include a healthy diet, regular exercise, and weight reduction as advised by your doctor.
The most common side effects of this medicine include nausea, vomiting, and increased liver enzymes. However, these are temporary and usually subside on their own. Please consult your doctor if these do not resolve or persist for a longer duration.
Before taking this medicine, inform your doctor if you have any kidney or liver problems or a urinary tract infection or if you are on water pills (diuretics). Pregnant or breastfeeding women should also consult their doctor before taking it. Avoid excessive alcohol intake while taking it as this may increase the risk of developing some side effects. Monitor your blood sugar levels regularly while taking this medicine.
Epalpex-M SR Tablet is a medicine used to treat long-lasting (chronic) pain caused by nerve damage due to diabetes. It reduces pain and its associated symptoms such as mood changes, sleep problems, and tiredness. It interferes with pain signals that travel through the damaged nerves and the brain and also improves nerve conduction. Taking Epalpex-M SR Tablet regularly will improve your physical and social functioning and overall quality of life.
Side effects of Epalpex-M Tablet SR
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Epalpex-M
Nausea
Vomiting
Increased liver enzymes
How to use Epalpex-M Tablet SR
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Epalpex-M SR Tablet may be taken with or without food, but it is better to take it at a fixed time.
How Epalpex-M Tablet SR works
Epalpex-M SR Tablet is a combination of two medicines:
Safety advice
Alcohol
UNSAFE
It is unsafe to consume alcohol with Epalpex-M SR Tablet.
Pregnancy
CONSULT YOUR DOCTOR
Epalpex-M SR Tablet may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Breast feeding
CONSULT YOUR DOCTOR
Information regarding the use of Epalpex-M SR Tablet during breastfeeding is not available. Please consult your doctor.
Driving
CONSULT YOUR DOCTOR
It is not known whether Epalpex-M SR Tablet alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react.
Kidney
CONSULT YOUR DOCTOR
There is limited information available on the use of Epalpex-M SR Tablet in patients with kidney disease. Please consult your doctor.
Liver
CONSULT YOUR DOCTOR
There is limited information available on the use of Epalpex-M SR Tablet in patients with liver disease. Please consult your doctor.
What if you forget to take Epalpex-M Tablet SR?
If you miss a dose of Epalpex-M SR Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
All substitutes
For informational purposes only. Consult a doctor before taking any medicines.
Take it only as per the dose and duration prescribed by your doctor.
Adherence to antidiabetic therapy can delay the onset of or prevent diabetic nerve disease.
Inform your doctor if you have:
Cut or sore on your feet that is infectious or not healing
Burning or tingling sensation in arm or feet that hamper your routine activities
Trouble in digestion, urination, or sexual functioning
Dizziness
To prevent diabetic nerve pain, wear proper footwear and examine your feet every day to detect lesions early.
Monitor your blood sugar level regularly.
Inform your doctor if you are pregnant, planning pregnancy or breastfeeding.
Fact Box
Habit Forming
No
Therapeutic Class
ANTI DIABETIC
Patient concerns
My dad is a diabetic patient now a days he is also suffering from leg pains associated with nerve pains from back side of left leg. How do i over come with this kind of situation to reduce the pains and keep it normal.
I have some serious back pain issue,for about 2 years now,sometimes it eases a bit but worsen more often. I feel the pain severely only after my afternoon sleep. Currently for around last one year having only zerodol th8 tablets to get some relief . Yet for last one week the pain is not easing even after having the tablet twice daily. Can you please help.
Dr. Mehtab Baig
Orthopaedic Physiotherapy
Stop zerodol tab. Do a m. R. I. First,M. R. I. Of whole spine
Burning sensation in sole ,penile region regularly No spot at penile area but constant burning sensation at sole and penile area No relief from amoxicillin,ceprofloxin doxycyclene Period :last 14 days
Dr. Pranay Gandhi
Sexology
that may be a neuropathic pain. do u have high bp or diabetes. take tablet pregama m 1 od for 15 days
Epalpex-M SR Tablet is mainly used to treat diabetic neuropathy, a nerve problem caused by diabetes that can lead to pain, tingling, numbness, or weakness—especially in the legs and feet.
Who should not take Epalpex-M SR Tablet?
Individuals should not take Epalpex-M SR Tablet if they are allergic to vitamin B12 or any ingredient in the medicine, have a rare inherited eye condition called Leber's hereditary optic neuropathy (which causes vision loss), or toxic optic neuropathy related to tobacco use. Also, do not use it if you have diabetic ketoacidosis (a serious diabetes complication).
Can Epalpex-M SR Tablet cause serious side effects?
Although they are rare, serious side effects of Epalpex-M SR Tablet include skin rash, itching, nausea, stomach pain, headaches, dizziness, fatigue, severe confusion, extreme tiredness, or allergic reactions (swelling, trouble breathing). Seek medical help immediately if you experience any of these symptoms.
What should I do if I suspect an Epalpex-M SR Tablet overdose?
Symptoms of Epalpex-M SR Tablet overdose may include extreme fatigue, confusion, and significant gastrointestinal discomfort. If you suspect an overdose, seek emergency medical attention immediately.
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References
Sharma SR, Sharma N. Epalrestat, an aldose reductase inhibitor, in diabetic neuropathy: An Indian perspective. Ann Indian Acad Neurol. 2008;11(4):231-35. [Accecssed 08 Apr. 2019] (online) Available from:
National Institues of Health. Vitamin B12. [Accessed 08 Apr. 2019] (online) Available from:
Hotta N, Akanuma Y, Kawamori R, et al. Long-term clinical effects of epalrestat, an aldose reductase inhibitor, on diabetic peripheral neuropathy: the 3-year, multicenter, comparative Aldose Reductase Inhibitor-Diabetes Complications Trial. Diabetes Care. 2006;29(7):1538-44. [Accessed 08 Apr. 2019] (online) Available from:
Marketer details
Name: Shilpex Pharmysis
Address: A-1, Ground Floor, Fie, Patparganj, New Delhi , New Delhi
Country of origin: India Expires on or after: January, 2026
A licensed vendor partner from your nearest location will deliver Epalpex-M SR Tablet. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's ℞ and the availability of this medicine.
In case of any issues, contact us
Email ID:[email protected] Phone Number: 0124-4166666 Address: 5th Floor Tower - B of the Presidency Building, 46/4 Mehrauli Gurgaon Road, Sector 14, Gurugram, Haryana-122001, India