Content Details
Written By
MDS (Oral Pathology & Microbiology), BDS
Reviewed By
MD (Pharmacology), MBBS
Last updated on:
22 May 2019 | 11:38 AM (IST)
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Overview

Introduction

Epalrica-M Tablet SR is a medicine used in the treatment of diabetic nerve disease. It protects the nerve fibers from damage and promotes regeneration of nerve cells. It is used along with other blood sugar lowering medications in order to prevent further nerve injury.

Uses of Epalrica-M Tablet SR

Epalrica-M Tablet SR side effects

Common
  • Nausea
  • Vomiting
  • Increased liver enzymes

How to use Epalrica-M Tablet SR

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Epalrica-M Tablet SR may be taken with or without food, but it is better to take it at a fixed time.

How Epalrica-M Tablet SR works

Epalrica-M Tablet SR is a combination of two medicines: Epalrestat and methylcobalamin which treat diabetic nerve disease. Epalrestat is an aldose reductase inhibitor. It blocks the accumulation of sorbitol in cells, which has been related in causing diabetic nerve disease. Methylcobalamin is a form of vitamin B which helps in the production of myelin, a substance that protects nerve fibers and rejuvenates damaged nerve cells.

Epalrica-M Tablet SR related warnings

Alcohol
Interaction with alcohol is unknown. Please consult your doctor.
Pregnancy
WEIGH RISKS VS BENEFITS
Epalrica-M Tablet SR may be unsafe to use during pregnancy.
Animal studies have shown adverse effects on the fetus, however, there are limited human studies. The benefits from use in pregnant women may be acceptable despite the risk. Please consult your doctor.
Lactation
No information is available on the use of Epalrica-M Tablet SR during lactation. Please consult your doctor.
Driving
It is not known whether Epalrica-M Tablet SR alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react.
Kidney
There is limited information available on the use of Epalrica-M Tablet SR in patients with kidney disease. Please consult your doctor.
Liver
There is limited information available on the use of Epalrica-M Tablet SR in patients with liver disease. Please consult your doctor.

Alternate Brands

For informational purposes only. Consult a doctor before taking any medicines.
Epalrica-M Tablet SR
₹20.93/Tablet SR
Epineuron SR Tablet
Aristo Pharmaceuticals Pvt Ltd
₹18/Tablet SR
save 14%
₹23.17/Tablet SR
11% costlier
Alrista Plus Tablet SR
Macleods Pharmaceuticals Pvt Ltd
₹18.9/Tablet SR
save 10%
Epalpex-M SR Tablet
Shilpex Pharmysis
₹24.25/Tablet SR
16% costlier

Expert Advice

  • Take it only as per the dose and duration prescribed by your doctor. 
  • Adherence to antidiabetic therapy can delay the onset of or prevent diabetic nerve disease.
  • Inform your doctor if you have:
    • Cut or sore on your feet that is infectious or not healing
    • Burning or tingling sensation in arm or feet that hamper your routine activities
    • Trouble in digestion, urination, or sexual functioning
    • Dizziness
  • To prevent diabetic nerve pain, wear proper footwear and examine your feet every day to detect lesions early.
  • Monitor your blood sugar level regularly.
  • Inform your doctor if you are pregnant, planning pregnancy or breastfeeding.

Patient Concerns

Questions Related to Epalrica-M

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I m 41 years n in to telecom profession. I m facing nerve pain (left or right arm, legs etc) from last few months. Pain persist for few second and then goes off but it happes atleast 2 to 6 times a day. Please suggest
Dr. Vikas Sharma
Neurologist
Tab oxetol 150 mg bd
I am suffering from sciatica nerve pain
Dr. Mehtab Baig
Physiotherapist
How many days, have you any m. R i. Or xray reports send meU can do all exercises 10 times twice a day before meals
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Do you have any questions related to Epalrica-M Tablet SR?

User Feedback


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Disclaimer: 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover all possible side effects, drug interactions or warnings or alerts. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.
References
  1. Sharma SR, Sharma N. Epalrestat, an aldose reductase inhibitor, in diabetic neuropathy: An Indian perspective. Ann Indian Acad Neurol. 2008;11(4):231-35. [Accecssed 08 Apr. 2019] (online) Available from:External Link
  2. National Institues of Health. Vitamin B12. [Accessed 08 Apr. 2019] (online) Available from:External Link
  3. Hotta N, Akanuma Y, Kawamori R, et al. Long-term clinical effects of epalrestat, an aldose reductase inhibitor, on diabetic peripheral neuropathy: the 3-year, multicenter, comparative Aldose Reductase Inhibitor-Diabetes Complications Trial. Diabetes Care. 2006;29(7):1538-44. [Accessed 08 Apr. 2019] (online) Available from:External Link
Manufacturer/Marketer Address
Exeltis - Ordain Health Care Global Pvt Ltd , Khivraj Complex - II, 4th Floor, No: 480, Anna Salai, Nandanam, Chennai - 600 035, Tamil Nadu, India.
A licensed pharmacy from your nearest location will deliver Epalrica-M Tablet SR. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your prescription and the availability of this medicine.
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