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MD (Pharmacology), MBBS
Last updated:
27 Dec 2019 | 03:51 PM (IST)
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Epalpex 150 SR Tablet

Prescription Required

Overview

Introduction

Epalpex 150 SR Tablet is used to treat diabetic nerve pain. Poorly controlled diabetes can eventually lead to diabetic nerve disease (neuropathy) as a complication. This medicine helps to relieve symptoms like burning pain and numbness seen in people with diabetic nerve disease.

Epalpex 150 SR Tablet belongs to a group of medicines known as Aldose reductase inhibitors. It can be taken with or without food but you should try to take it at the same time every day. This will help you to remember to take it. The dose and how often you need it will be decided by your doctor so that you get the right amount to control your symptoms. It may take up to 3 months to get the full benefits of this medicine, but you should keep taking it regularly.  Do not stop taking it without asking your doctor, otherwise, your condition may worsen.

This medicine is only part of a treatment program that should also include a healthy diet, regular exercise, and weight reduction as advised by your doctor. You should also continue taking other medicines prescribed by your doctor for blood sugar control. Keeping your blood sugar levels under control will help this medication work better.

The most common side effects of this medicine include nausea, vomiting, and abnormalities in liver function tests (increased liver enzymes). Most side effects are temporary and improve as your body gets used to the medicine. Please consult your doctor if any of these bother you or do not go away.

Before taking this medicine, let your doctor know if you have any kidney or liver problems. Pregnant or breastfeeding women should also consult their doctor before taking this medicine. Avoid any alcohol intake while taking it as this may increase the risk of developing some side effects.

Uses of Epalpex Tablet SR

Side effects of Epalpex Tablet SR

Common
  • Nausea
  • Vomiting
  • Liver function abnormal

How to use Epalpex Tablet SR

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Epalpex 150 SR Tablet may be taken with or without food, but it is better to take it at a fixed time.

How Epalpex Tablet SR works

Epalpex 150 SR Tablet is an aldose reductase inhibitor. It blocks the accumulation of sorbitol in cells, which has been related to causing diabetic nerve disease.

Safety Advice

Alcohol
UNSAFE
It is unsafe to consume alcohol with Epalpex 150 SR Tablet.
Pregnancy
CONSULT YOUR DOCTOR
Information regarding the use of Epalpex 150 SR Tablet during pregnancy is not available. Please consult your doctor.
Breastfeeding
CONSULT YOUR DOCTOR
Information regarding the use of Epalpex 150 SR Tablet during breastfeeding is not available. Please consult your doctor.
Driving
CONSULT YOUR DOCTOR
It is not known whether Epalpex 150 SR Tablet alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react.
Kidney
CONSULT YOUR DOCTOR
There is limited information available on the use of Epalpex 150 SR Tablet in patients with kidney disease. Please consult your doctor.
Liver
CONSULT YOUR DOCTOR
There is limited information available on the use of Epalpex 150 SR Tablet in patients with liver disease. Please consult your doctor.

What if you forget to take Epalpex Tablet SR?

If you miss a dose of Epalpex 150 SR Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

Alternate Brands

For informational purposes only. Consult a doctor before taking any medicines.
Epalpex 150 SR Tablet
₹19.7/Tablet SR
Aldonil OD Tablet
Zydus Cadila
₹21.17/Tablet SR
7% costlier
Alrista SR Tablet
Macleods Pharmaceuticals Pvt Ltd
₹12.8/Tablet SR
save 35%
Epo 150 Tablet SR
Frankfurt Pharma Pvt Ltd
₹19/Tablet SR
save 4%
Listap 150 SR Tablet
Vivid Biotek Pvt Ltd
₹27.5/Tablet SR
40% costlier
₹18.3/Tablet SR
save 7%

Quick Tips

  • Adherence to antidiabetic therapy can delay the onset of or prevent diabetic nerve disease.
  • If you have existing diabetic nerve disease, wear proper footwear and examine your feet every day to detect lesions early.
  • If you have a foot injury or open wound, avoid engaging in weight-bearing activities.

Patient Concerns

arrow
excessive nerve pain and sudden back pai
Dr. Vikas Sharma
Neurology
get examined; start tab tolifast 150 mg bd
Pain near left hand elbow, shoulder, loss of sensation near finger & back pain
Dr. Kamal Rijhwani
Physician
Start voveran sr tablet twice a day
arrow
Do you have any questions related to Epalpex 150 SR Tablet ?

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Disclaimer: 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover all possible side effects, drug interactions or warnings or alerts. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.
References
  1. Ramirez MA, Borja NL. Epalrestat: An aldose reductase inhibitor for the treatment of diabetic neuropathy. Pharmacotherapy. 2008;28(5):646-55. [Accessed 18 Mar. 2019] (online) Available from:External Link
  2. Hotta N, Akanuma Y, Kawamori R, et al. Long-term clinical effects of epalrestat, an aldose reductase inhibitor, on diabetic peripheral neuropathy: the 3-year, multicenter, comparative Aldose Reductase Inhibitor-Diabetes Complications Trial. Diabetes Care. 2006;29(7):1538-44. [Accessed 27 Mar. 2017] (online) Available from:External Link
Manufacturer/Marketer Address
11/56B, Malabar Hill Road, Mulund, Mumbai-82
A licensed pharmacy from your nearest location will deliver Epalpex 150 SR Tablet. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your prescription and the availability of this medicine.
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