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Alrista SR Tablet

Written By Dr. Subita Alagh, BDS
Reviewed By Dr. Sachin Gupta, MD Pharmacology, MBBS
Last updated on 13 Mar 2026 | 01:39 PM (IST)
Alrista SR Tablet is used to treat diabetic nerve pain. Poorly controlled diabetes can eventually lead to diabetic nerve disease (neuropathy) as a complication. This medicine helps to relieve symptoms like burning pain and numbness seen in people with diabetic nerve disease.
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General Information

Contains

Epalrestat (150mg)

Marketer

Macleods Pharmaceuticals Pvt Ltd

Storage

Store below 30°C
The content is shown in English
Alrista SR Tablet image
Alrista SR Tablet image
Alrista SR Tablet image
Alrista SR Tablet image
Alrista SR Tablet image
Alrista SR Tablet image
Alrista SR Tablet image

Product introduction

Alrista SR Tablet belongs to a group of medicines known as Aldose reductase inhibitors. It can be taken with or without food but you should try to take it at the same time every day. This will help you to remember to take it. The dose and how often you need it will be decided by your doctor so that you get the right amount to control your symptoms. It may take up to 3 months to get the full benefits of this medicine, but you should keep taking it regularly.  Do not stop taking it without asking your doctor, otherwise, your condition may worsen.

This medicine is only part of a treatment program that should also include a healthy diet, regular exercise, and weight reduction as advised by your doctor. You should also continue taking other medicines prescribed by your doctor for blood sugar control. Keeping your blood sugar levels under control will help this medication work better.

The most common side effects of this medicine include nausea, vomiting, and abnormalities in liver function tests (increased liver enzymes). Most side effects are temporary and improve as your body gets used to the medicine. Please consult your doctor if any of these bother you or do not go away.

Before taking this medicine, let your doctor know if you have any kidney or liver problems. Pregnant or breastfeeding women should also consult their doctor before taking this medicine. Avoid any alcohol intake while taking it as this may increase the risk of developing some side effects.

Uses of Alrista Tablet SR

Benefits of Alrista Tablet SR

Diabetic nerve pain
Diabetic nerve pain (diabetic neuropathy) is a common complication of diabetes that causes burning, tingling, or numbness, especially in the feet and legs. Alrista SR Tablet is used to help relieve these symptoms by protecting nerves from damage caused by high blood sugar. It aids in improving nerve function and reducing discomfort, allowing better mobility and quality of life for people with diabetes.

Side effects of Alrista Tablet SR

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Alrista
  • Nausea
  • Vomiting
  • Abnormal liver function

How to use Alrista Tablet SR

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Alrista SR Tablet may be taken with or without food.

How Alrista Tablet SR works

Alrista SR Tablet is an aldose reductase inhibitor. It blocks the accumulation of sorbitol in cells, which has been related to causing diabetic nerve disease.

All substitutes for Alrista SR Tablet

For information purposes only. Consult a doctor before taking any medicine.

Aldonil OD Tablet

by Zydus Cadila
₹28.9/tablet sr
80% costlier
<h3 class=bodySemiBold>Aldonil OD Tablet</h3>

Nurestat 150SR Tablet

by Chemo Healthcare Pvt Ltd
₹21.7/tablet sr
35% costlier
<h3 class=bodySemiBold>Nurestat 150SR Tablet</h3>

Quick tips

  • Adherence to antidiabetic therapy can delay the onset of or prevent diabetic nerve disease.
  • If you have existing diabetic nerve disease, wear proper footwear and examine your feet every day to detect lesions early.
  • If you have a foot injury or open wound, avoid engaging in weight-bearing activities.

Safety advice

Alcohol

Alcohol

CAUTION
Alcohol should be used with caution while taking Alrista SR Tablet.
Pregnancy

Pregnancy

CONSULT YOUR DOCTOR
The safety of Alrista SR Tablet during pregnancy has not been established. There are no adequate and well-controlled studies in pregnant women, and animal data on reproductive toxicity are insufficient. Your doctor will weigh the benefits and any potential risks before prescribing.
Breast feeding

Breast feeding

CONSULT YOUR DOCTOR
Alrista SR Tablet may be unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby. It should be used only if the expected benefit outweighs the potential risk. Please consult your doctor.
Driving

Driving

CONSULT YOUR DOCTOR
It is not known whether Alrista SR Tablet alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react. Please consult your doctor.
Kidney

Kidney

CAUTION
Alrista SR Tablet should be used with caution in patients with severe kidney disease. Dose adjustment may be needed.
Liver

Liver

CAUTION
Alrista SR Tablet should be used with caution in patients with liver disease. Dose adjustment may be needed.

Frequently asked questions

Alrista SR Tablet is used to treat nerve damage caused by diabetes, also known as diabetic neuropathy. It helps improve symptoms such as numbness, tingling, burning pain, and reduced sensation in the hands and feet by protecting and improving nerve function.
Individuals should not take Alrista SR Tablet if they are allergic to it, are pregnant or breastfeeding, unless advised by their doctor, or have severe liver problems. It is also not recommended for children unless specifically prescribed.
Before starting Alrista SR Tablet, tell your doctor if you have liver problems, kidney issues, or other medical conditions. Regular blood tests may be needed to monitor your liver function during treatment.
Although they are rare, serious side effects of Alrista SR Tablet include serious allergic reactions, severe skin rashes, and significant liver problems. Seek medical help immediately if you notice yellowing of the skin or eyes, severe itching, or swelling.
Alrista SR Tablet cannot cure diabetic neuropathy, but it can help slow its progression and reduce symptoms. It works best when combined with good blood sugar control and a healthy lifestyle.
Improvement in nerve symptoms may take several weeks to months during Alrista SR Tablet treatment, depending on the severity of the condition and how well blood sugar is controlled during treatment.

Fact Box

Chemical Class

Carboxylic acid derivative

Habit Forming

No

Therapeutic Class

ANTI DIABETIC

Action Class

Aldose Reductase Inhibitors (ARIs)

Related lab tests

Glycosylated Hemoglobin

References

  1. Ramirez MA, Borja NL. Epalrestat: An aldose reductase inhibitor for the treatment of diabetic neuropathy. Pharmacotherapy. 2008;28(5):646-55. [Accessed 18 Mar. 2019] (online) Available from:
  2. Hotta N, Akanuma Y, Kawamori R, et al. Long-term clinical effects of epalrestat, an aldose reductase inhibitor, on diabetic peripheral neuropathy: the 3-year, multicenter, comparative Aldose Reductase Inhibitor-Diabetes Complications Trial. Diabetes Care. 2006;29(7):1538-44. [Accessed 27 Mar. 2017] (online) Available from:
  3. MIMS, Malaysia. Epalrestat. [Accessed 25 Jul. 2024] (online) Available from:
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User feedback

Once A Day
100%
Diabetic nerve pain
93%
Others
7%
Average
52%
Poor
48%
Nausea
40%
No Side Effect
40%
Abnormal liver function
20%
With food
83%
With or without food
17%
Not Expensive
39%
Average
33%
Expensive
28%
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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Macleods Pharmaceuticals Pvt Ltd
Address: Atlanta Arcade, Marol Church Road, Andheri (East), Mumbai - 400059, INDIA.

Vendor Details

Country of origin: India
A licensed vendor partner from your nearest location will deliver Alrista SR Tablet. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's ℞ and the availability of this medicine.

In case of any issues, contact us

Email ID: [email protected]
Phone Number: 0124-4166666
Address: 5th Floor Tower - B of the Presidency Building, 46/4 Mehrauli Gurgaon Road, Sector 14, Gurugram, Haryana-122001, India

Lab tests offered by us

Why we need a prescription?
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Prescriptions are complex documents. We proof read and recheck at various steps to provide you the right medication in the correct form and dose
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In accordance with the law
Most medicines cannot be sold without a valid prescription, as per the Drugs and Cosmetics Act, 1940 and Rules, 1945
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