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MD (Pharmacology), MBBS
Last updated:
18 Feb 2020 | 05:26 PM (IST)
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Overview

Introduction

Entrogyl Tablet is used to treat diarrhea and abdominal pain. It works effectively to reduce abdominal pain, bloating, and cramps by relaxing the muscles of the stomach and gut. It neutralizes excessive acid in the stomach and helps in easy passage of gas. It also kills diarrhea-causing bacteria.

Entrogyl Tablet is taken with or without food in a dose and duration as advised by the doctor. The dose you are given will depend on your condition and how you respond to the medicine. You should keep taking this medicine for as long as your doctor recommends. If you stop treatment too early your symptoms may come back and your condition may worsen. Let your healthcare team know about all other medications you are taking as some may affect, or be affected by this medicine.

The most common side effects are nausea, metallic taste, diarrhea, dryness in mouth, vomiting, stomach pain, flatulence, weakness, nervousness, headache, and blurred vision. Most of these are temporary and usually resolve with time. Contact your doctor straight away if you are at all concerned about any of these side effects. It may also cause dizziness and sleepiness, so do not drive or do anything that requires mental focus until you know how this medicine affects you. Avoid drinking alcohol while taking this medicine as it can worsen your dizziness.

Before taking this medicine, you should tell your doctor if you are pregnant, planning pregnancy or breastfeeding. You should also tell your doctor if you have any kidney or liver diseases so that your doctor can prescribe a suitable dose for you. Immediately consult your doctor if you experience any allergic reactions such as skin rash, swelling, and itching.

Uses of Entrogyl Tablet

Side effects of Entrogyl Tablet

Common
  • Nausea
  • Metallic taste
  • Diarrhea
  • Dryness in mouth
  • Vomiting
  • Stomach pain
  • Flatulence
  • Sleepiness
  • Weakness
  • Nervousness
  • Headache
  • Dizziness
  • Blurred vision

How to cope with side effects?

The occurrence of side effects varies from person to person. The following are a few ways of dealing with some of the common side effects. However, consult your doctor if these persist.

  • Coping with Nausea
    You can help yourself by eating small, frequent meals rather than large ones and drinking plenty of fluids. Eat slowly. Avoid fatty, fried, spicy and very sweet foods. Eat cold or slightly warm food if the smell of cooked or cooking food makes you feel sick. Get plenty of fresh air. You could also try chewing ginger or drinking ginger tea. Eat bananas to replace potassium in your blood which can drop if you are sick (vomit). Use oral rehydration salts to replace vitamins and minerals lost through being sick. There are some medicines that can help you stop from feeling sick. Speak to your doctor if your condition does not improve.
  • Coping with Metallic taste
    Keep your mouth clean. Brush your teeth and rinse your mouth with saltwater or mouthwash after each snack or meal. Use plastic or glass utensils if the food tastes like metal. Avoid very hot or very cold foods. Chewing mints or gums may also help in improving the taste. Increase your fluid intake and choose foods that have strong flavors. Try adding garlic, lemon juice, herbs, spices and pickles or chutneys. Avoid cigarette smoking.
  • Coping with Diarrhea
    Keep up your intake of fluids and electrolytes (sugars and salts) to avoid getting dehydrated. Eat less fiber (avoid raw fruits, fruit juice and vegetables). Talk to your doctor about possible medication to manage diarrhea. Ask about reducing the dosage of your drug or other suitable treatments.
  • Coping with Dryness in mouth
    Keep a drink available that you can sip through the day. Rinse your mouth with warm salted water and chew sugarless gum or hard candy. Try breathing through your nose more often than your mouth. Avoid caffeinated beverages, smoking and alcohol because they can make your condition worse. Use lip balm if your lips are also dry. Try to avoid foods that are acidic (like lemons), spicy, salty or sugary. If this side effect bothers you or does not go away, talk to your doctor about artificial saliva products or other suitable treatments.
  • Coping with Vomiting
    You can help yourself by eating small, frequent meals rather than large ones and drinking plenty of fluids. Eat slowly. Avoid fatty, fried, spicy and very sweet foods. Eat cold or slightly warm food if the smell of cooked or cooking food makes you feel sick. Get plenty of fresh air. You could also try chewing ginger or drinking ginger tea. Eat bananas to replace potassium in your blood which can drop if you are sick (vomit). Use oral rehydration salts to replace vitamins and minerals lost through being sick. There are some medicines that can help you stop feeling sick. Speak to your doctor if your condition does not improve.
  • Coping with Stomach pain
    Try to get plenty of rest and relax. Putting a heat pad or covered hot water bottle on your stomach may relieve the stomach pain. It may help if you eat and drink slowly and have smaller and more frequent meals. Reduce your intake of coffee, tea and alcohol as these can make the pain worse. If you are in a lot of pain, speak to your doctor about possible medication. Your doctor may be able to prescribe some over-the-counter medicines to help reduce the pain.
  • Coping with Flatulence
    Try eating small and frequent meals. Drink and chew your food slowly. Exercise regularly to improve how your body digests food. Try not to swallow too much air. This can happen when you talk and eat at the same time. Avoid drinking with a straw, chewing gum and smoking as these can also make you swallow air. Try to limit foods that are hard to digest or produce gas (such as fried and fatty foods, cheese, beans, cabbage, onion, whole grains and many others). Avoid drinking alcohol, carbonated soft drinks and fruit juices. If you wear dentures, make sure they fit properly. Some over-the-counter medicines can help. Talk to your doctor about possible medication if your condition does not improve.
  • Coping with Sleepiness
    If the medicine is making you drowsy during the day, stop what you are doing and sit or lie down until you feel better. You can also consider taking a nap. Physical exercises such as walking may be helpful. Do not drink alcohol, as it will make you feel more tired. Avoid driving or operating heavy equipment when you are feeling drowsy. This problem usually goes away as your body gets used to the medicine. However, if it does not, ask your doctor if you can take your medicine at bedtime or whether the dose can be reduced.
  • Coping with Weakness
    Make sure you rest and drink plenty of fluids. Eat a well-balanced diet to keep your energy levels up. Do not drink too much alcohol. Do not drive or use tools or machinery until you feel better. Other things that can help include doing some gentle exercise every day, prioritizing and pacing your activities and having a short nap if you need to. If you are still having problems after a week, speak to your doctor, as they may want to change you to a different type of medicine.
  • Coping with Nervousness
    This often disappears when the condition you are being treated for is managed. You could ask your doctor about changing the dose of your medicine or alternatives if it is affecting your daily life or causing you distress. Psychological treatments may be available. Some things you can do to help yourself include stopping smoking, cutting down the amount of alcohol and caffeine you drink, and doing regular exercise. You should also eat a healthy diet and find out how to get sleep if you are having trouble. Try talking to a friend or family member. Calming breathing exercises and other relaxation techniques may also help.
  • Coping with Headache
    Make sure you rest and drink plenty of fluids. Rest in a quiet, dimly lit room. Do not sleep more than you normally would. Do not strain your eyes (for example by looking at a screen). Do not drink alcohol. Headaches are usually temporary and usually go away with time. But, if they last longer or get worse, ask your doctor to recommend a painkiller.
  • Coping with Dizziness
    This is usually short-lived and should go away within a few days. If this happens, stop what you are doing and sit or lie down until you feel better. Lying still in a dark, quiet room may help reduce the spinning feeling. Sleep with your head slightly raised on two or more pillows. Get up slowly from a lying or sitting position. Get plenty of rest and try to relax as being anxious can make it worse. Try taking this medicine at bedtime to reduce the symptoms. Drinking plenty of water and ginger tea may also help. Avoid alcohol, caffeine and smoking as it will make you feel worse. Avoid driving or using tools or machinery until you feel better.
  • Coping with Blurred vision
    You can consider washing your eyes with water. Avoid driving or using tools or machines if your vision is impaired. Do not take your next dose if your vision is still blurry. If it gets worse or does not improve, ask your doctor to recommend eye drops or talk about changing your medications.

How to use Entrogyl Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Entrogyl Tablet may be taken with or without food, but it is better to take it at a fixed time.

How Entrogyl Tablet works

Entrogyl Tablet is a combination of four medicines: Activated Dimethicone/Simethicone, Dicyclomine, Diloxanide and Tinidazole which treat intestinal infections. Activated Dimethicone/Simethicone is an antifoaming medicine which disintegrates gas bubbles and allows easy passage of gas. Dicyclomine is an antispasmodic which works by relaxing the muscles in your stomach and gut (intestine). It stops sudden muscle contractions (spasms). In doing this, it relieves cramps, pain, bloating, and discomfort.is a luminal amoebicide which acts inside the intestines to kill the infection-causing microorganisms (amoeba). Diloxanide is combined with tinidazole in case of severe intestinal infections. Tinidazole is an antibiotic which kills bacteria and other infectious microorganisms by damaging the DNA.

Safety Advice

Alcohol
UNSAFE
Consuming alcohol while taking Entrogyl Tablet may cause symptoms such as flushing, increased heart beat, nausea, thirst, chest pain and low blood pressure (Disulfiram reaction).
Pregnancy
CONSULT YOUR DOCTOR
Entrogyl Tablet may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Breastfeeding
CONSULT YOUR DOCTOR
Information regarding the use of Entrogyl Tablet during breastfeeding is not available. Please consult your doctor.
Driving
UNSAFE
Entrogyl Tablet may cause side effects which could affect your ability to drive.
Entrogyl Tablet may make you feel drowsy or gives you problems with coordination or sensation (e.g. numbness or weakness). This may affect your driving ability.
Kidney
CAUTION
Entrogyl Tablet should be used with caution in patients with kidney disease. Dose adjustment of Entrogyl Tablet may be needed. Please consult your doctor.
Liver
SAFE IF PRESCRIBED
Entrogyl Tablet is probably safe to use in patients with liver disease. Limited data available suggests that dose adjustment of Entrogyl Tablet may not be needed in these patients. Please consult your doctor.

Alternate Brands

For informational purposes only. Consult a doctor before taking any medicines.
No alternate brands found for this medicine

Quick Tips

  • Take it as per dose and duration suggested by the doctor. 
  • Avoid taking alcohol as it can further increase the side effects of medicine.
  • Do not skip doses and finish the prescribed course, even if you start to feel better. Stopping it early may increase your risk of further infection.
  • Inform your doctor if you notice severe allergic reaction like skin rash, swelling, and itching.
  • Inform your doctor if you are pregnant, planning pregnancy or breastfeeding.

Patient Concerns

arrow
Fever,diarrhea, abdominal pain
Dr. Pranav Gupta
Paediatrics
Please use PARACETAMOL for fever and WHO-ORS for diarrhoea. If no relief or worsening, please see a doctor
Is lopox tab is safe for dirreah
Dr. Gopal Samdani
Paediatrics
Below are the common side effects that may occur when using Lopox Tablet. Please consult your doctor if you observe any of these side effects even in mild form. Abdominal distention Abdominal pain Constipation Difficulties in urinationThere are some moreSo not very safe in bacterial diarrhea
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Do you have any questions related to Entrogyl Tablet ?

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References
  1. Mayo Clinic. Simethicone. [Accessed 31 Jan. 2019] (online) Available from:External Link
  2. Tinidazole. Sandwich, Kent: Pfizer Limited; 2006. [revised 06/2016]. (online) Available from:External Link
  3. Simethicone. Princeton. New Jersey: Bracoo Diagnostic. [Accessed 15 Apr. 2019] (online) Available from:External Link
  4. Dicyclomine. Birmingham, Alabama: Axcan Scandipharm Inc.; 2005. [Accessed 15 Apr. 2019] (online) Available from:External Link
  5. Drugs.com. Diloxanide. [Accessed 15 Apr. 2019] (online) Available from:External Link
  6. Drugs.com. Tinidazole. [Accessed 14 Apr. 2019] (online) Available from:External Link
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