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Duprost Capsule

Dutasteride (0.5mg)

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Duprost Capsule is used in the treatment of benign prostatic hyperplasia. It shrinks the size of the enlarged prostate gland to relieve symptoms like pain and difficulty in passing urine.

Written By Dr. Syeda Aafia, MBA, BDS,
Reviewed By Dr. Rajeev Sharma, MBA, MBBS,
Last updated on 13 Apr 2026 | 10:23 AM (IST)

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General Information

Contains

Dutasteride (0.5mg)

Marketer

Cipla Ltd

Storage

Store below 25°C

The content is shown in English

Product introduction

Duprost Capsule should be taken by mouth with or without food. This medicine is given for a long time and takes a few months to show its effects. Thus, it is important to take it as advised by the doctor and complete the full course of treatment.

Common side effects of Duprost Capsule include low sexual drive, ejaculation disorder, breast enlargement, and breast tenderness. If any of these side effects bother you, consult your doctor for guidance.

It is advised not to donate blood for 6 months after taking the last dose of Duprost Capsule. Let your doctor know if you have any other preexisting medical conditions before using this medicine. Let your doctor also know if you have a history of allergic reactions to any of the ingredients in this medicine. Duprost Capsule is not indicated for use in women.

Uses of Duprost Capsule

Benign prostatic hyperplasia

Benefits of Duprost Capsule

Benign prostatic hyperplasia
Benign prostatic hyperplasia (BPH) is a non-cancerous enlargement of the prostate gland, common in older men. It can press on the urethra and cause problems like frequent urination, difficulty starting or stopping urine flow, and a weak stream. Duprost Capsule helps shrink the enlarged prostate over time, easing these urinary symptoms and reducing the need for surgery. It can also lower the risk of urinary retention, offering long-term relief and improved quality of life.

Side effects of Duprost Capsule

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Duprost

Breast tenderness in male
Impotence
Decreased libido
Ejaculation disorder
Breast enlargement in male

How to use Duprost Capsule

Take this medicine in the dose and duration as advised by your doctor. Duprost Capsule may be taken with or without food.

How Duprost Capsule works

Duprost Capsule is a 5-alpha reductase inhibitor. It blocks an enzyme that is necessary to change testosterone to another hormone that causes the prostate to grow. As a result, it helps to shrink the prostate and relieve symptoms like difficulty in passing urine.

All substitutes for Duprost Capsule

For information purposes only. Consult a doctor before taking any medicine.

Dutas Capsule

by Dr Reddy's Laboratories Ltd

₹44.27/capsule

43% costlier

Dutafast 0.5mg Capsule

by Aethicz Biolife

₹8.2/capsule

73% cheaper

Quick tips

Duprost Capsule may take 3 to 6 months to see the full beneficial effect of Duprost Capsule. Hence, continue taking the medicine as advised by your doctor.
Duprost Capsule is usually well tolerated. However, it may produce some mild sexual side effects, such as low sexual drive.
Do not donate blood for 6 months after taking the last dose of Duprost Capsule.

Safety advice

Alcohol

CONSULT YOUR DOCTOR

It is not known whether it is safe to consume alcohol with Duprost Capsule. Please consult your doctor.

Pregnancy

UNSAFE

Duprost Capsule is highly unsafe during pregnancy. It can cause serious harm to the unborn baby, including birth defects and pregnancy loss. Do not use this medicine if you are pregnant or planning to become pregnant.
Duprost Capsule is contraindicated in women. Partners should use protection during intercourse.

Breast feeding

UNSAFE

Duprost Capsule is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.
Duprost Capsule is not indicated for use in women.

Driving

SAFE

Duprost Capsule does not usually affect your ability to drive.

Kidney

SAFE IF PRESCRIBED

Duprost Capsule is probably safe to use in patients with kidney disease. Limited data suggest dose adjustment may not be needed.

Liver

CONSULT YOUR DOCTOR

There is limited data available on the use of Duprost Capsule in patients with liver disease.
Use of Duprost Capsule is not recommended in patients with severe liver disease.

Interaction with drugs

Taking Duprost with any of the following medicines can modify the effect of either of them and cause some undesirable side effects

Moderate

Aprepitant (Oral Route)

Watch out for symptoms such as reduced sexual drive, dizziness, blisters or mood changes and consult your doctor if you experience them. They may monitor and adjust the doses as per the observations. Aprepitant may raise blood levels of Dutasteride.

Moderate

Aprepitant (Injection Route)

Moderate

Atazanavir (Oral Route)

Moderate

Cholestyramine (Oral Route)

To take Dutasteride, ensure a gap of 1 hour before and 6 hours after taking Cholestyramine. Cholestyramine may reduce the efficacy of Dutasteride.

Moderate

Conivaptan (Injection Route)

Frequently asked questions

What is Duprost Capsule used for?

Duprost Capsule is used to treat enlarged prostate (benign prostatic hyperplasia or BPH) in men. It helps improve urination, reduces the risk of urinary blockage, and may lower the chance of needing prostate surgery.

What are the most serious side effects of Duprost Capsule?

Some rare but serious side effects of Duprost Capsule include high-grade prostate cancer, allergic reactions (rash, swelling, breathing trouble), breast changes (lumps, pain, enlargement), and sexual problems like erectile dysfunction or low sex drive. If you notice any of these, contact your doctor.

Can Duprost Capsule affect fertility or semen quality?

Yes. Duprost Capsule can reduce sperm count, semen volume, and sperm movement. These effects may lower fertility, but they usually improve after stopping the Duprost Capsule treatment.

Can Duprost Capsule affect PSA test results for prostate cancer?

Yes. Duprost Capsule lowers PSA levels by about 50 percent, which could hide early signs of prostate cancer. Tell your doctor you are taking Duprost Capsule before doing a PSA test.

Can I donate blood while on Duprost Capsule?

No. You should not donate blood until at least 6 months after your last Duprost Capsule dose. This helps prevent the drug from being passed, including to pregnant women, through transfusion.

Is Duprost Capsule used to prevent prostate cancer?

No, Duprost Capsule is not approved for preventing prostate cancer, and it may slightly increase the risk of a more aggressive type of prostate cancer in some men.

How long does Duprost Capsule take to work?

The exact time Duprost Capsule takes to show results is not known. However, it may take 3 to 6 months to see noticeable improvement in symptoms, as the prostate shrinks gradually over time.

Can Duprost Capsule be taken with other medications?

Yes, it’s often combined with tamsulosin for better symptom relief. However, always check with your doctor before mixing medications.

Do I have to take Duprost Capsule forever?

You may need to take Duprost Capsule long-term to keep symptoms under control. Stopping the medication on your own could allow your prostate to grow again. Your doctor will guide you on how long to take it.

Fact Box

Chemical Class

Androgen derivative

Habit Forming

Therapeutic Class

UROLOGY

Action Class

5-Alpha Reductase Inhibitors (5ARIs)

References

Chrousos GP. The Gonadal Hormones & Inhibitors. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. p. 723.
Dutasteride. Research Triangle Park, North Carolina: GlaxoSmithKline; 2001 [revised Jun. 2008]. [Accessed 04 Apr. 2019] (online) Available from:
Central Drugs Standard Control Organisation (CDSCO). [Accessed 04 Apr. 2019] (online) Available from:
Dutasteride [Product Monograph]. Mississauga, Ontario: GlaxoSmithKline Inc.; 2013. [Accessed 20 June 2023]. (online) Available from:
CiplaMed: Dutasteride [Prescribing Information]. 2013. [Accessed 06 Mar. 2025]. (online) Available from:

User feedback

Patients taking Duprost Capsule

Once A Day

81%

Thrice A week

Alternate Day

Twice A Day

Twice A Week

Once A Week

What are you using Duprost Capsule for?

Others

50%

Benign prostatic hyperplasia

50%

How much was the improvement?

Poor

54%

Average

38%

Excellent

What were the side-effects while using Duprost Capsule?

Decreased libido

33%

Decreased semen volume

33%

No Side Effect

33%

How do you take Duprost Capsule?

With or without food

67%

With food

33%

Please rate Duprost Capsule on price

Average

50%

Not Expensive

50%

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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Cipla Ltd
Address: Cipla House, Peninsula Business Park, Ganpatrao Kadam Marg, Lower Parel, Mumbai-400013

Vendor Details

Country of origin: India
A licensed vendor partner from your nearest location will deliver Duprost Capsule. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's ℞ and the availability of this medicine.

In case of any issues, contact us

Email ID: [email protected]
Phone Number: 0124-4166666
Address: 5th Floor Tower - B of the Presidency Building, 46/4 Mehrauli Gurgaon Road, Sector 14, Gurugram, Haryana-122001, India

Lab tests offered by us

Why we need a prescription?

Duprost Capsule

Cash on delivery

Free Return

Expiry after

Save more with additional offers

General Information

Contains

Marketer

Storage

Product introduction

Uses of Duprost Capsule

Benefits of Duprost Capsule

Side effects of Duprost Capsule

How to use Duprost Capsule

How Duprost Capsule works

All substitutes for Duprost Capsule

Dutas Capsule

Dutafast 0.5mg Capsule

Quick tips

Safety advice

Alcohol

Pregnancy

Breast feeding

Driving

Kidney

Liver

Interaction with drugs

Aprepitant (Oral Route)

Aprepitant (Injection Route)

Atazanavir (Oral Route)

Cholestyramine (Oral Route)

Conivaptan (Injection Route)

Frequently asked questions

What is Duprost Capsule used for?

What are the most serious side effects of Duprost Capsule?

Can Duprost Capsule affect fertility or semen quality?

Can Duprost Capsule affect PSA test results for prostate cancer?

Can I donate blood while on Duprost Capsule?

Is Duprost Capsule used to prevent prostate cancer?

How long does Duprost Capsule take to work?

Can Duprost Capsule be taken with other medications?

Do I have to take Duprost Capsule forever?

Fact Box

Chemical Class

Habit Forming

Therapeutic Class

Action Class

References

User feedback

Patients taking Duprost Capsule

What are you using Duprost Capsule for?

How much was the improvement?

What were the side-effects while using Duprost Capsule?

How do you take Duprost Capsule?

Please rate Duprost Capsule on price

Want to know more

Have issue with the content

Disclaimer

Marketer details

Vendor Details

In case of any issues, contact us

Lab tests offered by us

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