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Duovir EP 150mg/300mg Tablet

Written By Dr. Sakshi Jain, MS, BDS
Reviewed By Dr. Sachin Gupta, MD Pharmacology, MBBS
Last updated on 07 Apr 2026 | 03:01 PM (IST)
Duovir EP 150mg/300mg Tablet is a combination of two antiretrovirals. It is prescribed to treat HIV (human immunodeficiency virus) infection. It boosts up the immunity to fight against HIV to manage or treat AIDS (acquired immunodeficiency syndrome).
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General Information

The content is shown in English
Duovir EP 150mg/300mg Tablet image
Duovir EP 150mg/300mg Tablet image

Product introduction

Duovir EP 150mg/300mg Tablet restricts the growth of HIV in the body and reduces the risk of getting HIV-related complications to improve the lifespan of an individual. The medicine can be taken with or without food. Taking these medicines regularly at the same time increases their effectiveness. A dose of this medicine should not be missed as it can affect your recovery. It is important to complete the full course of the treatment until your doctor advises you to stop it.

Some of the most common side effects of this medicine are nausea, diarrhea, headaches, and fatigue. These side effects are generally temporary, but if they persist or become serious inform your doctor. This medicine can also make you feel dizzy or sleepy, so it is advised to avoid driving. Drinking plenty of fluid can help you to cope up with this side effect, so stay hydrated.

Before starting with the treatment, you should consult your doctor if you are pregnant or breastfeeding, or have any health condition. Your doctor may suggest regular laboratory tests to check your blood counts, kidney and liver functions, and other health conditions. If you are HIV positive, you should not breastfeed or share personal belongings like razors or toothbrushes. Consult your doctor to know about safe sex methods in order to prevent transmission of HIV during intercourse.

Uses of Duovir EP Tablet

Benefits of Duovir EP Tablet

HIV infection
Duovir EP 150mg/300mg Tablet prevents the HIV virus from multiplying in your body. It helps control the infection and makes your immune system work better. This lowers your chances of getting complications such as new infections and improves your quality of life.

It is not a cure of HIV or AIDS and should not be used to prevent HIV after accidental exposure to a risk. It is important that you take this medicine as prescribed, following the dosage recommended by your doctor. Taking all doses in the right amount at the right times greatly increases the effectiveness of your combination of medicines and reduces the chances of your HIV infection becoming resistant to antiretroviral medicines. However, taking this medicine will not prevent you from passing HIV to other people.

Side effects of Duovir EP Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Duovir EP
  • Hypersensitivity
  • Nausea
  • Diarrhea
  • Decreased appetite
  • Abdominal pain
  • Abdominal cramp
  • Indigestion
  • Hair loss
  • Fever
  • Loss of appetite
  • Vomiting
  • Headache
  • Fatigue
  • Cough
  • Insomnia (difficulty in sleeping)
  • Rash
  • Joint pain
  • Gastrointestinal disturbance
  • Muscle disorders
  • General discomfort

How to use Duovir EP Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Duovir EP 150mg/300mg Tablet may be taken with or without food.

How Duovir EP Tablet works

Duovir EP 150mg/300mg Tablet is a combination of two anti-HIV medicines: Lamivudine and Zidovudine. They prevent HIV (virus) from multiplying, thereby reducing the amount of virus in your body. They also increase the CD4 cell (white blood cells that protect against infection) count in your blood.

All substitutes for Duovir EP 150mg/300mg Tablet

For information purposes only. Consult a doctor before taking any medicine.

Quick tips

  • Duovir EP 150mg/300mg Tablet is a combination of two medicines which slows down or stops the progression of HIV infections.
  • It may also be used for preventing HIV and should be started within 72 hours of exposure to HIV.
  • Take it with food, as this increases the absorption of the medicine into the body.
  • Duovir EP 150mg/300mg Tablet may cause dizziness or sleepiness. Do not drive or do anything requiring concentration until you know how it affects you.
  • Skipping doses increases the risk of treatment failure. Make sure that you take all your doses at the correct time.
  • Always practice safe sex while taking Duovir EP 150mg/300mg Tablet. Do not share needles or personal items that can have blood or body fluids on them.
  • It may cause weakening of your bones. Exercise regularly and take calcium and vitamin D supplements as suggested by your doctor.

Safety advice

Alcohol

Alcohol

UNSAFE
It is unsafe to consume alcohol with Duovir EP 150mg/300mg Tablet
Pregnancy

Pregnancy

CONSULT YOUR DOCTOR
The safety of Duovir EP 150mg/300mg Tablet during pregnancy has not been established. There are no adequate and well-controlled studies in pregnant women, and animal data on reproductive toxicity are insufficient. Your doctor will weigh the benefits and any potential risks before prescribing.
Breast feeding

Breast feeding

UNSAFE
Duovir EP 150mg/300mg Tablet is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.
Driving

Driving

CONSULT YOUR DOCTOR
It is not known whether Duovir EP 150mg/300mg Tablet alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react. Please consult your doctor.
Kidney

Kidney

CAUTION
Duovir EP 150mg/300mg Tablet should be used with caution in patients with severe kidney disease. Dose adjustment may be needed.
Liver

Liver

UNSAFE
Duovir EP 150mg/300mg Tablet is unsafe to use in patients with liver disease and should be avoided.
Use of Duovir EP 150mg/300mg Tablet is not recommended in patients with moderate to severe liver disease.

Frequently asked questions

Duovir EP 150mg/300mg Tablet is a combination of two medicines that belong to a group of medicines called antiretrovirals. It is used to treat HIV (human immunodeficiency virus), the virus that can cause AIDS (acquired immunodeficiency syndrome). It helps to control HIV infection so your immune system can work better.
Duovir EP 150mg/300mg Tablet prevents the multiplication of the virus in human cells. This stops the virus from producing new viruses and clears up your infection.
Duovir EP 150mg/300mg Tablet is safe if used in the dose and duration advised by your doctor. Take it exactly as directed and do not skip any dose. Follow your doctor's instructions carefully and let your doctor know if any of the side effects bother you.
Duovir EP 150mg/300mg Tablet should be taken in the dose and duration advised by the doctor. This medicine is to be taken on an empty stomach to get maximum benefit. It is better to take Duovir EP 150mg/300mg Tablet at a fixed time of the day to avoid the chances of missing a dose.
Duovir EP 150mg/300mg Tablet is effective if used in the dose and duration advised by your doctor. Do not stop taking it even if you see improvement in your condition. If you stop using Duovir EP 150mg/300mg Tablet too early, the symptoms may return or worsen.
If you forget a dose of Duovir EP 150mg/300mg Tablet, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and take the next scheduled dose in the prescribed time. Do not double the dose to make up for the missed one as this may increase the chances of developing side effects.

Fact Box

Habit Forming

No

Therapeutic Class

ANTI INFECTIVES
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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Cipla Ltd
Address: Cipla House, Peninsula Business Park, Ganpatrao Kadam Marg, Lower Parel, Mumbai-400013

Vendor Details

Country of origin: India
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