Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Duotrol 2.5mg/500mg Tablet SR is to be taken with food. This medicine may cause stomach upset if taken empty stomach.
Duotrol 2.5mg/500mg Tablet SR is a combination of two antidiabetic medicines: Glibenclamide and Metformin. Glibenclamide is a sulfonylurea which works by increasing the amount of insulin released by the pancreas in order to lower the blood glucose. Metformin is a biguanide which works by lowering glucose production in the liver, delaying glucose absorption from intestines and increasing the body's sensitivity to insulin.
Taking metformin with alcohol can cause lactic acidosis and you may experience malaise, respiratory distress, slow or irregular heartbeat, sleepiness, stomach upset, or other unusual symptoms.
Duotrol 2.5mg/500mg Tablet SR is probably safe to use during pregnancy. Animal studies have shown low or no adverse effect on the foetus, however, there are limited human studies. Please consult your doctor.
Duotrol 2.5mg/500mg Tablet SR is probably safe to use during lactation.
Limited human data suggests that the drug does not represent a significant risk to the baby.
Your ability to drive may be affected if your blood sugar is low or high. If this happens, do not drive.
Duotrol 2.5mg/500mg Tablet SR is probably unsafe to use in patients with kidney disease and should be avoided. Please consult your doctor.
Duotrol 2.5mg/500mg Tablet SR should be used with caution in patients with liver disease. Dose adjustment of Duotrol 2.5mg/500mg Tablet SR may be needed. Please consult your doctor. Duotrol 2.5mg/500mg Tablet SR is generally started with low dose in patients with mild to moderate liver disease and its use is not recommended in patients with severe liver disease.
“The following are the results of on-going survey on 1mg.com for Duotrol 2.5mg/500mg Tablet SR. These results only indicate the perceptions of the website users. Please base your medical decisions only on the advice of a doctor or a registered medical professional.”
Information last updated by Dr. Varun Gupta, MD Pharmacology on 7th May 2018.