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MD (Pharmacology), MBBS
Last updated:
13 Apr 2021 | 01:41 AM (IST)

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Duopules 1.25mg/500mcg Respules

Prescription Required

Introduction

Duopules 1.25mg/500mcg Respules is used for the treatment of chronic obstructive pulmonary disorder (a lung disorder in which the flow of air to the lungs is blocked). It helps in relaxing the muscles of the air passages and making it easier to breathe. It relieves coughing, wheezing and feeling short of breath.

Your doctor will tell you how often you need to use your inhaler. The effect of this medicine may be noticeable after a few days but will only reach its maximum after a few weeks. This medicine must be used regularly to be effective, so go on taking it even if you don't have any symptoms. That means it’s doing its job. If you stop taking it your COPD may get worse. This medicine should not be used to relieve sudden shortness of breath. If sudden shortness of breath occurs, use your rescue inhaler. To get the benefit from this medicine you need to make sure you get your inhaler technique right, otherwise, it Does not work as well.

The most common side effects are dryness in mouth, shortness of breath, cough, tremor, headache, palpitations, and muscle cramp. If you get there, don’t stop taking it but do talk to your doctor. You can prevent some of these symptoms by rinsing your mouth and throat with water or brushing your teeth after using your inhaler. There are other, rarer side effects which can be serious. Talk to your doctor if you're worried about them.

Before taking it, you should tell your doctor if you have any kidney or liver diseases so that your doctor can prescribe a suitable dose for you. Also tell your doctor if you are pregnant, planning pregnancy or breastfeeding.

Benefits of Duopules Respules

In Chronic obstructive pulmonary disease (COPD)

Duopules 1.25mg/500mcg Respules is a combination of medicines that helps the airways in your lungs stay open. They work by relaxing the muscles of these airways. This makes it easier for air to get in and out. It will relieve symptoms such as tightness in your chest, shortness of breath, wheezing and coughing and help you carry out your daily activities more easily.
Duopules 1.25mg/500mcg Respules is a safe and effective medicine. It usually starts to work within a few minutes and the effects can last up to several hours. Do not stop using it unless you are advised to by your doctor. You need to use your inhaler correctly for it to work properly. If you are not sure, ask your doctor or nurse.

Side effects of Duopules Respules

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Duopules

  • Dryness in mouth
  • Breathlessness
  • Cough
  • Tremor
  • Headache
  • Palpitations
  • Muscle cramp

How to use Duopules Respules

Use this medicine in the dose and duration as advised by your doctor. Check the label for directions before use. Twist off the top of the respule/transpule and squeeze all the liquid into the nebulizer. It should be used right away after opening.

How Duopules Respules works

Duopules 1.25mg/500mcg Respules is a combination of two medicines: Levosalbutamol and Ipratropium. Levosalbutamol is a bronchodilator while Ipratropium is an anticholinergic. They work by relaxing the muscles in the airways and widen the airways. Together, they make breathing easier.

Safety Advice

Alcohol
UNSAFE
Duopules 1.25mg/500mcg Respules may cause excessive drowsiness with alcohol.
Pregnancy
CONSULT YOUR DOCTOR
Duopules 1.25mg/500mcg Respules may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Breastfeeding
SAFE IF PRESCRIBED
Duopules 1.25mg/500mcg Respules is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.
Driving
No interaction found/established
Kidney
No interaction found/established
Liver
No interaction found/established

What if you forget to take Duopules Respules?

If you miss a dose of Duopules 1.25mg/500mcg Respules, use it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

Alternate Brands

For informational purposes only. Consult a doctor before taking any medicines.
Duopules 1.25mg/500mcg Respules
₹25.0/Respules
₹10.8/Respules
57% cheaper
Duojet 1.25mg/500mcg Respules
Brinton Pharmaceuticals Pvt Ltd
₹13.03/Respules
48% cheaper
Duosules 1.25mg/500mcg Respules
May and Baker Pharmaceuticals Ltd
₹23/Respules
8% cheaper
Iprazest Respules
Macleods Pharmaceuticals Pvt Ltd
₹41.1/Respules
64% costlier
₹55/Respules
120% costlier

Quick Tips

  • Duopules 1.25mg/500mcg Respules is a combination of two medicines that makes breathing easier for patients with chronic obstructive pulmonary disease (COPD).
  • This medicine is for inhalation only. The tablet should not be swallowed.
  • It should be taken at the same time each day.
  • It does not work right away and should not be used to relieve sudden breathing problems. Use your rescue inhaler to control sudden difficulty in breathing. 
  • Dry mouth may occur as a side effect. Frequent mouth rinses, good oral hygiene, increased water intake and sugarless candy may help.
  • Gargle with warm water after each inhalation to avoid any fungal infections in your mouth and throat.
  • Take the first dose of this medicine under medical supervision as it may cause wheezing or tightening of the airways (bronchospasm) immediately after using.
  • Your doctor may regularly monitor your  blood potassium level as low oxygen level in the blood (hypoxia) and medicines such as Duopules 1.25mg/500mcg Respules can lower blood potassium level.
  • Only miniscule amounts of Duopules 1.25mg/500mcg Respules may get absorbed into the bloodstream after inhalation. Hence, serious side effects are unlikely.

Fact Box

Habit Forming
No
Therapeutic Class
RESPIRATORY

Patient Concerns

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i m suffering from breathing problem cough chest infame . Do tell chronic obstructive pulmonary disease .So tell which medicines should i take to treat this problem.
Dr. Anshum Aneja Arora
Pulmonology
It is less likely you have copd at this age You need detailed check up and spirometry test for same
What is chronic pulmonary thromboembolism?
Dr. Saurabh Arora
Cardiology
U can Google for details
arrow
Do you have any questions related to Duopules 1.25mg/500mcg Respules ?

FAQs

Q. Are there any medicines which I should avoid while taking Duopules 1.25mg/500mcg Respules?

It is not recommended to use Duopules 1.25mg/500mcg Respules along with other medicines, such as anticholinergic, beta-adrenergic agents, beta-blockers, diuretics, digoxin, MAO inhibitors or anti-depressants.

Q. Will Duopules 1.25mg/500mcg Respules be more effective if taken in higher doses?

No, taking a higher than the recommended dose of this medicine will not make it more effective, rather can lead to increased side effects. If the symptoms do not get relieved by the recommended doses, please consult the doctor for re-evaluation.

Q. Can the use of Duopules 1.25mg/500mcg Respules cause sleepiness or drowsiness?

Yes, Duopules 1.25mg/500mcg Respules may make you feel drowsy or sleepy. Avoid driving, operating machinery, working at heights, or participating in potentially dangerous activities at the beginning of your treatment until you know how the medicine affects you. Inform your doctor if you experience such episodes while you are taking this medicine.

Q. Can the use of Duopules 1.25mg/500mcg Respules cause dry mouth?

Yes, the use of Duopules 1.25mg/500mcg Respules can cause dry mouth. If you experience dry mouth, drink plenty of water. Take regular sips during the day and keep some water by your bed at night.

Q. What are the instructions for storage and disposal of Duopules 1.25mg/500mcg Respules?

Keep this medicine in the container it came in, tightly closed. Store it according to the instructions mentioned on the pack or label. Dispose of the unused medicine. Make sure it is not consumed by pets, children and other people.

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1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover all possible side effects, drug interactions or warnings or alerts. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

References

  1. Levalbuterol. Marlborough, MA: Sunovion Pharmaceuticals Inc; 1999. [Accessed 17 Apr. 2019] (online) Available from:External Link
  2. Ipratropium. Bracknell Berkshire: Boehringer Ingelheim Limited; 2004 [revised Feb. 2018]. [Accessed 01 Apr. 2019] (online) Available from:External Link
  3. Drugs.com. Levalbuterol. [Accessed 17 Apr. 2019] (online) Available from:External Link
  4. Drugs.com. Ipratropium. [Accessed 17 Apr. 2019] (online) Available from:External Link

Manufacturer/Marketer Address

“Elder House” Plot No. C-9, Dalia Industrial Estate, Off Veera Desai Road, Andheri (W), Mumbai – 400053.
MRP
25
Inclusive of all taxes
2.5 ml in 1 packet
SOLD OUT

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