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MRP: Rs. 49 for 1 strip(s) (10 tablets each)
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Composition for DIAGRM

Gliclazide(40 mg),Metformin(NA),Rosiglitazone(NA)

food interaction for DIAGRM

alcohol interaction for DIAGRM

pregnancy interaction for DIAGRM

lactation interaction for DIAGRM

There is no data available. Please consult doctor before consuming the drug.
Taking metformin with alcohol may cause lactic acidosis and you may experience malaise, respiratory distress, slow or irregular heartbeat, somnolence, abdominal upset, or other unusual symptoms.
Taking rosiglitazone with alcohol may affect blood glucose levels in patients with diabetes.
Diagrm tablet may be unsafe to use during pregnancy.
Either animal studies have shown adverse effect on fetus and there are no human studies or studies in human and animals are not available. It should be given only if potential benefits justifies risk to the fetus. Please consult your doctor.
Diagrm tablet is probably unsafe to use during breastfeeding. Please consult your doctor.


Gliclazide(40 mg)


Gliclazide is used to lower the blood sugar levels in type 2 diabetes mellitus when diet, physical exercise and weight reduction alone are not adequate. 

How it works

Gliclazide belongs to a blood sugar lowering group of medicines called sulfonylurea. Gliclazide increases the amount of insulin released by the pancreas, and thereby decreases the blood sugar level.

Common side effects

Nausea, Abdominal pain, Abnormal blood cell, Angioedema (swelling of deeper layers of skin), Blisters on skin, Skin peeling, Constipation, Decreased blood cell count, Diarrhoea, Decreased sugar level in blood, Indigestion, Rash, Visual impairment, Vomiting


Metformin is an antidiabetic medicine that helps to control blood sugar in people with type 2 diabetes mellitus.

How it works

Metformin belongs to class of medications called antidiabetics.It decreases the amount of glucose absorbed from the food and the amount ofglucose made by liver. Metformin also increases the body's response to insulin(a natural substance that controls the amount of glucose in the blood).

Common side effects

Flatulence, Muscle pain, Abdominal bloating, Chest pain, Skin rash, Flushing, Abdominal pain, Nail disorder, Diarrhoea, Headache, Indigestion, Bitter taste, Constipation, Allergic reaction, Heartburn


Type 2 diabetes mellitus.

How it works

Rosiglitazone acts as an agonist at peroxisome proliferator activated receptors (PPAR) in target tissues for insulin action such as adipose tissue, skeletal muscle, and liver. Activation of PPAR-gamma receptors regulates the transcription of insulin-responsive genes involved in the control of glucose production, transport, and utilization. In this way, rosiglitazone enhances tissue sensitivity to insulin.

Common side effects

Vomiting, Nausea, Back pain, Cardiac disorder, Cold symptoms, Nasal congestion, Fluid retention, Limb swelling, Headache, Loss of appetite, Running nose, Sore throat, Stomach pain


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Expert advice for DIAGRM

  • Do not chew the tablet, and swallow the whole tablet with a glass of water or non-alcoholic drink just before a meal.
  • Do not take gliclazide, if you have type 1 diabetes mellitus or have impaired consciousness due to severe diabetes, liver or kidney disease, or deficiency of an enzyme called glucose-6-phosphate dehydrogenase.
  • Do not take gliclazide if you are pregnant or breast-feeding.

Frequently asked questions for DIAGRM


Q. Is gliclazide same or, better than metformin?
Gliclazide and metformin belong to different class of drugs and act but separate mechanism. No significant difference between gliclazide and metformin was reported in clinical studies as regards their ability to reduce blood sugar.
Q. Is gliclazide the same as glipizide?
No,gliclazide and glipizide belong to a class of drugs known as sulphonylureas.
Q. Is gliclazide a statin or, steroid?
No,gliclazide belongs to sulfonylurea category of antidiabetic drug class.
Q. What is Glizid M?
Glizid M is a combination product that contains gliclazide and metformin. Both drugs are used to lower blood glucose levels in adult with type 2 diabetes mellitus that is not controlled by diet and exercise alone.


Q. Is Metformin a birth control pill/ insulin / statin/ banned drug?
Metformin (also available as glyciphage, glycomet, glycomet SR) is an antidiabetic drug used in treatment of type 2 diabetes mellitus, particularly in overweight patients, as an adjunct to the diet and exercise.
Q. Is metformin safe?
Metformin is generally safe if used at prescribed doses for the prescribed duration as advised by your doctor.
Q. Can I take metformin forever?
Metformin should be taken at prescribed doses for the prescribed duration as advised by your doctor.
Q. Is metformin good for weight loss / weight loss in non-diabetics?
Metformin is used for the treatment of type 2 diabetes mellitus, particularly in overweight patients. 


Content on this page was last updated on 01 April, 2014, by Dr. Varun Gupta (MD Pharmacology)