Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Diagrm Tablet is to be taken with food. Diagrm Tablet may cause stomach upset if taken empty stomach.
Diagrm Tablet is a combination of three antidiabetic medicines: Gliclazide, Metformin and Rosiglitazone. They work by different mechanisms to provide better control of blood sugar when single or dual therapy is not effective. Gliclazide is a sulfonylurea which works by increasing the amount of insulin released by the pancreas in order to lower the blood glucose. Metformin is a biguanide. It works by lowering glucose production in the liver, delaying glucose absorption from intestines and increasing the body's sensitivity to insulin. Rosiglitazone is a thiazolidinedione which further increases insulin sensitivity.
Taking rosiglitazone with alcohol may affect blood glucose levels in patients with diabetes.
WEIGH RISKS VS BENEFITS
Diagrm Tablet may be unsafe to use during pregnancy. Animal studies have shown adverse effects on the foetus, however, there are limited human studies. The benefits from use in pregnant women may be acceptable despite the risk. Please consult your doctor.
No information is available on the use of Diagrm Tablet during lactation. Please consult your doctor.
Your ability to drive may be affected if your blood sugar is low or high. If this happens, do not drive.
Diagrm Tablet should be used with caution in patients with kidney disease. Dose adjustment of Diagrm Tablet may be needed. Please consult your doctor. Use of Diagrm Tablet is, however, not recommended in patients with severe kidney disease. Regular monitoring of kidney function test is advisable while you are taking this medicine.
Diagrm Tablet should be used with caution in patients with liver disease. Dose adjustment of Diagrm Tablet may be needed. Please consult your doctor. Inform your doctor if you develop any signs and symptoms of jaundice while taking this medicine.