Overview
Uses and benefits
Side effects
How to use
How drug works
Safety advice
Missed dose
All substitutes
Quick tips
Fact box
Patient concerns
FAQs

Author Details

Written By

Dr. Sakshi Jain

MS, BDS

Reviewed By

Dr. Rajeev Sharma

MBA, MBBS

Last updated

03 Dec 2025 | 10:59 PM (IST)

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Home>Dezil-Plus>dezil plus 5mg/5mg tablet

Dezil Plus 5mg/5mg Tablet

Prescription Required

Marketer

Ryon Pharma

SALT COMPOSITION

Donepezil (5mg) + Memantine (5mg)

Storage

Store below 30°C

View available alternative with same salt composition

Click here to view all substitutes

Product introduction

Dezil Plus 5mg/5mg Tablet is a prescription medicine used to treat Alzheimer's disease. It helps to slow down the progression of moderate to severe Alzheimer's by improving memory and thinking. It also increases the levels of a chemical messenger involved in the transmission of nerve signals.

Dezil Plus 5mg/5mg Tablet can be taken with or without food, but you may take it with food to avoid a stomach upset. However, it is advised to take it at the same time each day to maintain a consistent level of medicine in the blood. Do not skip any doses, but if you miss a dose of this medicine, take it as soon as you remember. Finish the full course of treatment even if you feel better and do not stop taking it suddenly.

Some common side effects of this medicine include nausea, vomiting, loss of appetite, fatigue, and headache. It may also cause dizziness and sleepiness. So, do not drive or do anything that requires mental focus until you know how this medicine affects you. Drink plenty of fluids to keep yourself hydrated while taking this medicine as this medicine may cause diarrhea.

Before using this medicine, you should tell your doctor if you have ever had heart problems, stomach ulcers, epilepsy or asthma. It may also affect, or be affected by, some other drugs you are using so let your doctor know what these are to be safe. Inform your doctor if you are pregnant, planning pregnancy or breastfeeding.

Uses of Dezil-Plus Tablet

Alzheimer's disease

Side effects of Dezil-Plus Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Dezil-Plus

Weight loss
Drug allergy
Balance disorder (loss of balance)
High blood pressure
Breathlessness
Diarrhea
Nausea
Muscle cramp
Dizziness
Headache
Insomnia (difficulty in sleeping)

How to use Dezil-Plus Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Dezil Plus 5mg/5mg Tablet may be taken with or without food.

How Dezil-Plus Tablet works

Dezil Plus 5mg/5mg Tablet is a combination of two medicines: Donepezil and Memantine which treat Alzheimer’s disease. Donepezil is a cholinesterase inhibitor while Memantine is an NMDA inhibitor. Together, they balance the levels of chemical messengers in the brain and help in the transmission of nerve signals.

Safety advice

Alcohol

CONSULT YOUR DOCTOR

It is not known whether it is safe to consume alcohol with Dezil Plus 5mg/5mg Tablet. Please consult your doctor.

Pregnancy

CONSULT YOUR DOCTOR

Dezil Plus 5mg/5mg Tablet is not recommended during pregnancy as there is positive evidence of fetal risk based on animal studies. However, it may still be prescribed by a doctor in situations where the benefits outweigh the risks.

Breast feeding

CONSULT YOUR DOCTOR

Information regarding the use of Dezil Plus 5mg/5mg Tablet during breastfeeding is not available. Please consult your doctor.

Driving

UNSAFE

Dezil Plus 5mg/5mg Tablet may decrease alertness, affect your vision, or make you feel sleepy and dizzy. Do not drive if these symptoms occur.

Kidney

CAUTION

Dezil Plus 5mg/5mg Tablet should be used with caution in patients with severe kidney disease. Dose adjustment may be needed.

Liver

CAUTION

Dezil Plus 5mg/5mg Tablet should be used with caution in patients with liver disease. Dose adjustment may be needed.

What if you forget to take Dezil-Plus Tablet?

If you miss a dose of Dezil Plus 5mg/5mg Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

All substitutes

For informational purposes only. Consult a doctor before taking any medicines.

Dezil Plus 5mg/5mg Tablet

₹9.39/Tablet

Donpezem M 5mg/5mg Tablet

Leeford Healthcare Ltd

₹12/tablet

28% costlier

Donamem 5 Tablet

Sun Pharmaceutical Industries Ltd

₹17.1/tablet

82% costlier

Alzil-M 5 Tablet

Intas Pharmaceuticals Ltd

₹21.8/tablet

132% costlier

Aricep-M Tablet

Eisai Pharmaceuticals India Pvt Ltd

₹13.8/tablet

47% costlier

Larentine D 5mg/5mg Tablet

La Renon Healthcare Pvt Ltd

₹13.9/tablet

48% costlier

Quick tips

Dezil Plus 5mg/5mg Tablet is used for the symptomatic treatment of alzheimer's disease. It does not cure alzheimer's, but may help with brain function and doing daily activities.
Monitor your body weight regularly as both Dezil Plus 5mg/5mg Tablet and alzheimer's disease can cause weight loss.
Don't drive or do anything that requires mental focus until you know how it affects you.
Inform your doctor if you have a history of seizures as it may raise the chances of seizure if you had them in the past.
It may cause stomach ulcers, specially if you are also taking medications for inflammation or pain. Talk to your doctor if you vomit blood or have black colored stools.

Fact Box

Habit Forming

Therapeutic Class

NEURO CNS

Patient concerns

I am suffering from severe head ache since 2 years

Dr. Ravindra Srivastava

Neuro Surgery

GET MRI BRAIN TO RULE OUT ICSOL. SLEEP FOR 8HRS A DAY. TAB .PROVALNOR PLUS 5MG AT BEDTIME.

Till last month I was ok but after taking naxito tablet 5mg for 10+days I found that I have developed erection problem and just for two days I had taken stugeron plus too along with Naxito 5mg but I have stopped taking naxito tablet 15 days back but erection has slightly improved but not as good as before taking Naxito tablet.

Dr. Pranay Gandhi

Sexology

hello. Treatment for erectile dysfunction: 1.stop smoking and alcohol 2.join a gym and reduce weight. Do weight lifting exercises. 3.tablet sildenafil or viagra 1 tablet 1 hour before sexual activity. 4.Get tested so that u don?t have any of the following causes: 1.heart diseases 2. diabetes 3.neurological problems 4.hormonal problems 5.drug side effectstablet dejac t 1 hr befr sex is better than anything u r taking

1)always conjusted nose results breathing problem 2)irratating cough on the throught round the day 3)cold immunity power continusly dropped from last 4/5 years 4) throught irritation started immedietly whenever taken some cold water or anything 5) I am always used to take 140 ml alcohol daly 6)my bread and butter way is very stressful throut the day 7) after two weeks i will go to high altitude hill station as a short tour please advise meicine for relif from breathing problem due to conjession of nasal hole.

Dr. Pushkar Mani

Physician

1-xylorex nasal spray thrice daily for 7 days, 2- azithromycin 500 mg once daily for 6 days , 3- becosule plus twice daily for 15 days, 4-cetcip 5mg twice daily for 5 days.stop alcohol under taking these medcine and stop drinking refrigerated cold water

What are the instructions for the storage and disposal of Dezil Plus 5mg/5mg Tablet?

Keep this medicine in the packet or container it came in, tightly closed. Store it as mentioned on the pack or label. Dispose of the unused medicine. Make sure it is not consumed by pets, children, and other people.

What are the contraindications to the use of Dezil Plus 5mg/5mg Tablet?

Dezil Plus 5mg/5mg Tablet is contraindicated in patients who are allergic to Memantine, Donepezil or any of its constituents. Also, inform your doctor about all of patients medical history before using this medicine.

What should I inform my doctor before using Dezil Plus 5mg/5mg Tablet?

Before taking Dezil Plus 5mg/5mg Tablet, tell the doctor about all of patient's past and present medical conditions, including: problem in heart, lung, liver, kidney or bladder, seizures, stomach ulcers or any scheduled medical procedures. Also, inform your doctor about all the medicines patient takes.

What if the patient takes more of Dezil Plus 5mg/5mg Tablet than recommended?

If the patient overdose on Dezil Plus 5mg/5mg Tablet, go to nearest medical emergency department or call your doctor immediately.

Can the use of Dezil Plus 5mg/5mg Tablet cause diarrhea?

Yes, the use of Dezil Plus 5mg/5mg Tablet can cause diarrhea. In case, the patient experience diarrhea, talk to the doctor. Do not take any other medicines without speaking to a doctor.

What should I inform my doctor before using Dezil Plus 5mg/5mg Tablet?

What if the patient takes more of Dezil Plus 5mg/5mg Tablet than recommended?

If the patient overdose on Dezil Plus 5mg/5mg Tablet, go to nearest medical emergency department or call your doctor immediately.

Can the use of Dezil Plus 5mg/5mg Tablet cause diarrhea?

Yes, the use of Dezil Plus 5mg/5mg Tablet can cause diarrhea. In case, the patient experience diarrhea, talk to the doctor. Do not take any other medicines without speaking to a doctor.

What are the instructions for the storage and disposal of Dezil Plus 5mg/5mg Tablet?

What are the contraindications to the use of Dezil Plus 5mg/5mg Tablet?

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