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Dexamethasone Sodium Phosphate Injection

Dexamethasone (NA)
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Dexamethasone Sodium Phosphate Injection belongs to a group of medicines called steroids. It is used in the treatment of various diseases and conditions such as inflammatory and autoimmune conditions. It provides relief from swelling, redness, and pain, by preventing the release of substances that cause inflammation.

Written By Dr. Lipika Khurana, PGDHHM, BDS,
Reviewed By Dr. Sachin Gupta, MD Pharmacology, MBBS,
Last updated on 25 Feb 2026 | 11:36 AM (IST)
₹72 MRP ₹79.6910% off 
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General Information

The content is shown in English
Dexamethasone Sodium Phosphate Injection image
Dexamethasone Sodium Phosphate Injection image

Product introduction

Dexamethasone Sodium Phosphate Injection is generally given by a doctor and should not be self-administered. You need to use it regularly to get the maximum benefit of the medicine. Complete the full course to get maximum benefits from the medicine.


The most common side effects of this medicine include fluid or electrolyte imbalance, musculoskeletal disturbances, gastrointestinal disorder, skin disorder, neurological disorders, menstrual disorders, and glaucoma. If you experience such symptoms that persist or worsen, or any other symptoms which you think may be due to the medicine, let your doctor know.


Dexamethasone Sodium Phosphate Injection can make it harder for you to fight off infections. Tell your doctor if you have any signs of infection, such as a fever or sore throat. Before taking the medicine, let your doctor know all the other medicines you are taking. Pregnant and breastfeeding mothers should ask the advice of their doctors before taking this medicine.

Uses of Dexamethasone Sodium Phosphate Injection

  • Treatment of Inflammatory conditions
  • Treatment of Autoimmune conditions

Benefits of Dexamethasone Sodium Phosphate Injection

Treatment of Inflammatory conditions
Dexamethasone Sodium Phosphate Injection gives relief in inflammatory conditions that affect muscles and joints such as arthritis and ankylosing spondylitis. It also helps manage other inflammatory conditions such as asthma, inflammatory bowel disease, uveitis, ulcerative colitis, and allergies. It works by blocking certain chemicals that cause pain and swelling.
Treatment of Autoimmune conditions
Dexamethasone Sodium Phosphate Injection gives relief in autoimmune conditions like psoriasis, rheumatoid arthritis, eczema, atopic dermatitis, etc. It works by lowering your immune system’s response to these conditions thereby reducing symptoms such as swelling, pain, itching, and other allergic-type reactions.

Side effects of Dexamethasone Sodium Phosphate Injection

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Dexamethasone Sodium Phosphate
  • Nervous system disorder

How to use Dexamethasone Sodium Phosphate Injection

Your doctor or nurse will give you this medicine. Kindly do not self administer.

How Dexamethasone Sodium Phosphate Injection works

Dexamethasone Sodium Phosphate Injection is a steroid which works by blocking the production of certain chemical messengers in the body that cause inflammation (redness and swelling) and allergies.

All substitutes for Dexamethasone Sodium Phosphate Injection

For information purposes only. Consult a doctor before taking any medicine.

Quick tips

  • Dexamethasone Sodium Phosphate Injection can make it harder for you to fight off infections. Notify your doctor if you have any signs of infection such as a fever or sore throat.
  • Stick to simple meals and have plenty of fluids while taking Dexamethasone Sodium Phosphate Injection.
  • Some vaccines might not be suitable for you while you are being treated with Dexamethasone Sodium Phosphate Injection. If you need any immunisations, make sure you mention that you are taking Dexamethasone Sodium Phosphate Injection.
  • You might experience trouble sleeping or headache. If any of these become troublesome, speak with your doctor.
  • Try to keep your regular appointments with your doctor. This is so your doctor can check on your progress.
  • Dexamethasone Sodium Phosphate Injection may cause weakness of arms and legs after a few months. Inform your doctor if it becomes severe and you are unable to do daily activities.

Safety advice

Alcohol

Alcohol

CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with Dexamethasone Sodium Phosphate Injection. Please consult your doctor.
Pregnancy

Pregnancy

CONSULT YOUR DOCTOR
Dexamethasone Sodium Phosphate Injection is not recommended during pregnancy as there is positive evidence of fetal risk based on animal studies. However, it may still be prescribed by a doctor in situations where the benefits outweigh the risks.
Breast feeding

Breast feeding

CAUTION
Dexamethasone Sodium Phosphate Injection should be used with caution during breastfeeding. Breastfeeding should be held until the treatment of the mother is completed and the drug is eliminated from the body.
Driving

Driving

CONSULT YOUR DOCTOR
It is not known whether Dexamethasone Sodium Phosphate Injection alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react. Please consult your doctor.
Kidney

Kidney

CAUTION
Dexamethasone Sodium Phosphate Injection should be used with caution in patients with severe kidney disease. Dose adjustment may be needed.
Regular monitoring of kidney function tests and other blood tests is advisable while you are taking Dexamethasone Sodium Phosphate Injection.
Liver

Liver

CAUTION
Dexamethasone Sodium Phosphate Injection should be used with caution in patients with severe liver disease. Dose adjustment may be needed.

Interaction with drugs

Taking Dexamethasone Sodium Phosphate with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
Severe

Herpes Zoster / Shingles Vaccine (Recombinant, Adjuvanted) (Injection Route)

Do not use Dexamethasone with Herpes Zoster / Shingles Vaccine (Recombinant, Adjuvanted). If essential, please consult your doctor. Dexamethasone may reduce efficacy of Herpes Zoster / Shingles Vaccine (Recombinant, Adjuvanted).
Severe

Purified Vi Polysaccharide Typhoid Vaccine (Injection Route)

It is recommended to wait at least 3 months after discontinuing a high dose of Dexamethasone before taking Purified Vi Polysaccharide Typhoid Vaccine.
Severe

Purified Vi Polysaccharide Typhoid Vaccine (null)

These should not be taken concomitantly. Please consult with your doctor about keeping appropriate gap between these two. Dexamethasone may reduce efficacy of Purified Vi Polysaccharide Typhoid Vaccine.
Severe

Axitinib (Oral Route)

Dexamethasone may reduce blood levels of Axitinib. Dexamethasone may reduce blood levels of Axitinib.
Moderate

Chloroquine (Oral Route)

Your doctor may monitor your potassium levels closely.

Frequently asked questions

Yes, Dexamethasone Sodium Phosphate Injection is a steroid medicine. It is also known as corticosteroids which occur naturally in the body and help to maintain health and wellbeing. Dexamethasone Sodium Phosphate Injection increases the levels of corticosteroids in the body which helps in treating various illnesses involving inflammation (redness, tenderness, heat and swelling).
Dexamethasone Sodium Phosphate Injection has anti-inflammatory and immunosuppressant properties. It is used to treat conditions like allergic conditions, anaphylaxis, asthma, rheumatoid arthritis, inflammatory skin diseases. It also helps to treat autoimmune diseases (these diseases happen when your body’s immune system attacks the body itself and causes damage) and certain eye disorders. Additionally, it is used to treat cancer and nephrotic syndrome when used in combination with other medications.
Dexamethasone Sodium Phosphate Injection should be administered by a doctor or under the supervision of a healthcare professional and should not be self-administered. Usually, it is given into a muscle (intramuscular), joint (intra-articular), directly into a vein (direct intravenous), infusion or into the area being treated (soft tissue infiltration). The dose will be decided by your doctor based on the condition you are being treated for as well as your body weight. Follow your doctor’s instructions carefully to get maximum benefit from Dexamethasone Sodium Phosphate Injection.
The medicine works by reducing the inflammation which helps in treating many illnesses caused due to active inflammation. Also, it stops the reactions known as autoimmune reactions which occur when your body's immune system attacks the body itself and causes damage.
Clinical studies have shown that Dexamethasone Sodium Phosphate Injection is a long-acting glucocorticoid. It is 6 times more potent than Prednisone. It stays in our body for a longer duration and is better tolerated when used in the treatment of inflammatory conditions. However, consult your doctor for the right treatment of your condition.

Fact Box

Chemical Class

21- hydroxysteroids

Habit Forming

No

Therapeutic Class

HORMONES

Action Class

Glucocorticoids
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User feedback

Once A Day
43%
Once A Month
14%
Once A Week
14%
Twice A Week
14%
Twice A Day
14%
Others
39%
Cancer
17%
Severe allergic reactions
13%
Allergic conditions
13%
Asthma
9%
Excellent
56%
Average
33%
Poor
11%
No Side Effect
75%
Mood changes
25%
Empty stomach
40%
With or without food
40%
With food
20%
Average
67%
Expensive
33%
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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Jagsonpal Pharmaceuticals Ltd
Address: T-210 J, Shahpur Jat, New Delhi - 110 049, India

Vendor Details

Country of origin: India
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