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Dermotrex 1% Gel

Prescription Required
Store at room temperature (10-30°C)


Dermotrex 1% Gel is a medicine used to treat a severe form of skin disease called psoriasis when other treatments are not effective. The medicine help kills the cells in the skin which are growing too quickly. It may be also used to treat other conditions, as determined by the doctor.

Dermotrex 1% Gel is only meant for external use and should be used as advised by your doctor. Your doctor will decide what dose is necessary and how often you need to use it. Do not stop using the medicine without first checking with your doctor. You should use it exactly as your doctor has advised.

The most common side effects of this medicine include nausea, vomiting, loss of appetite, and abdominal pain. If they do not go away or get worse, tell your doctor. There may be ways of preventing or reducing these effects. Before using it, tell your doctor if you have liver or kidney problems or are taking any medicines to treat infections. Many other medicines can affect, or be affected by, this medicine so let your doctor know all medications you are using. This medicine is not recommended during pregnancy or while breastfeeding. It can cause harm to your baby.

Uses of Dermotrex Gel

Benefits of Dermotrex Gel

In Psoriasis

Psoriasis is a condition where the skin cells in the body grow too quickly. Dermotrex 1% Gel is usually used to treat severe psoriasis when other treatments have not worked. It works by killing fast-growing cells and slowing down its rapid growth. Use it exactly as prescribed and for as long as it is prescribed to get the most benefit. Do not use more than you should. It may take several months to become fully effective. You should avoid drinking alcohol while having this treatment and drink plenty of water to stay hydrated.

Side effects of Dermotrex Gel

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Dermotrex

  • Nausea
  • Vomiting
  • Loss of appetite
  • Indigestion
  • Abdominal pain
  • Increased liver enzymes
  • Stomatitis (Inflammation of the mouth)

How to use Dermotrex Gel

This medicine is for external use only. Use it in the dose and duration as advised by your doctor. Check the label for directions before use. Clean and dry the affected area and apply the gel. Wash your hands after applying, unless hands are the affected area.

How Dermotrex Gel works

Dermotrex 1% Gel is an immunosuppressant. In psoriasis, it works by slowing down the rapid growth of skin cells.

Safety Advice

No interaction found/established
Dermotrex 1% Gel is highly unsafe to use during pregnancy. Seek your doctor's advice as studies on pregnant women and animals have shown significant harmful effects to the developing baby.
Dermotrex 1% Gel is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.
No interaction found/established
No interaction found/established
No interaction found/established

Alternate Brands

For informational purposes only. Consult a doctor before taking any medicines.
Dermotrex 1% Gel
₹14.67/gm of Gel
Rextop 1% Gel
Systopic Laboratories Pvt Ltd
₹12.5/gm of Gel
save 15%
Trexjoy Gel
Intas Pharmaceuticals Ltd
₹14.95/gm of Gel
2% costlier

Quick Tips

  • Take it once a week, on the same day every week.
  • Always take folic acid as advised by your doctor. This will help lessen the side effects of this medicine.
  • It may take 6 to 8 weeks for Dermotrex 1% Gel to work. Keep taking the medication as prescribed.
  • Avoid drinking alcohol while taking this medicine as it may increase the risk of side effects.
  • It can be harmful to an unborn baby. Avoid pregnancy for at least 6 months after your last dose.
  • Drink plenty of liquids to stay hydrated while taking this  medication.

Fact Box

Chemical Class
Glutamic Acid Derivative
Habit Forming
Therapeutic Class

Interaction with Drugs

Taking Dermotrex with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
Brand(s): Rotasiil, Rotarix, RotaTeq
Brand(s): Abhay M, Measles, M-Vac
Brand(s): Rubella

Patient Concerns

Skin psoriasis From last 1 year
Dr. Atula Gupta
cap maxepa once daily for 3 months . Pasitrex c ointment for application twice daily . physiogel as moisturiser . Stop smoking . Avoid stressnbuvb phototherapy can be done at clinic . Contact SkinAid Clinic Gurgaon for details . 9XXXXXX
I am suffering with psoriasis from past 1 year
Dr. Deepak Kumar Soni
Ayurveda this oil at least 2-3 months
Do you have any questions related to Dermotrex 1% Gel ?


Q. Is Dermotrex 1% Gel effective?

Dermotrex 1% Gel is effective if used in the dose and duration advised by your doctor. Do not stop using it even if you see improvement in your condition. If you stop using Dermotrex 1% Gel too early, the symptoms may return or worsen.

Q. How to use Dermotrex 1% Gel?

Before using Dermotrex 1% Gel, clean and dry the affected area. Gently and thoroughly massage it into the skin. Be careful not to get the medication in your eyes or mouth. If Dermotrex 1% Gel gets in your eyes accidentally, wash with plenty of water and call your doctor if your eyes are irritated.

Q. What precautions do I need to take while using Dermotrex 1% Gel?

Be careful not to get Dermotrex 1% Gel into your eyes or mouth. If you happen to get it in your eyes, rinse off with plenty of water immediately and contact your doctor. You must not use Dermotrex 1% Gel if you are allergic to it or any of its ingredients. Tell your doctor if you notice any allergic reaction while using it for the first time. Inform your doctor if you are taking any medicines regularly to prevent any allergic reaction with other medicines. Do not cover the area being treated with Dermotrex 1% Gel with a bandage, as this may increase absorption of this medicine and increase the side effects. Do not use more than what is recommended to relieve your symptoms faster. Using more than what is advised will only increase the side effects. Let your doctor know if you are planning to conceive to avoid any harm to the baby. Pregnant and breastfeeding mothers should use Dermotrex 1% Gel only if prescribed by the doctor.

Q. What should I do if I forget to use Dermotrex 1% Gel?

If you forget to use Dermotrex 1% Gel, do not worry and continue using Dermotrex 1% Gel as soon as you remember. Do not double the dose to make up for the missed dose. However, if you are not sure and have any other doubts, please consult your doctor.

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1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover all possible side effects, drug interactions or warnings or alerts. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.


  1. Chu E, Sartorelli AC. Cancer Chemotherapy. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. pp. 944-46.
  2. Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 887-90.
  3. Methotrexate Pregnancy and Breastfeeding Warnings. [Accessed 02 Apr. 2019] (online) Available from:External Link

Manufacturer/Marketer Address

No. 10, 2nd Cross, Maravaneri, Salem - 636007, Tamil Nadu.
Expires on or after: February, 2021

A licensed vendor partner from your nearest location will deliver Dermotrex 1% Gel. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's ℞ and the availability of this medicine.
MRP440  Get 15% OFF
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30 gm in 1 tube
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