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Defza 18 Tablet

Written By Dr. Subita Alagh, BDS
Reviewed By Dr. Sachin Gupta, MD Pharmacology, MBBS
Last updated on 12 Mar 2026 | 11:07 AM (IST)
Defza 18 Tablet is a corticosteroid medicine used in Duchenne muscular dystrophy. It helps reduce muscle inflammation and damage, supporting muscle strength and slowing the progression of muscle weakness over time.
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₹188 MRP ₹206.259% off 
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Defza 18 Tablet is currently sold out
Same composition alternative:
Defcort 18 Tablet
₹204₹221.7
Available alternative from Top Brand
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Defza 18 Tablet
Defza 18 Tablet
strip of 10 tablets
₹188
₹206.25
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Same composition
Defcort 18 Tablet
Defcort 18 Tablet
strip of 6 tablets
Deflazacort (18mg)
by Macleods Pharmaceuticals Pvt Ltd
₹204
₹28.83 per tablet

₹173

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₹1200

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General Information

Contains

Deflazacort (18mg)

Marketer

Wallace Pharmaceuticals Pvt Ltd

Storage

Store below 30°C
The content is shown in English
Defza 18 Tablet image
Defza 18 Tablet image

Product introduction

Defza 18 Tablet works by inhibiting the release of substances that cause swelling or by changing how the immune system works. It can be taken on an empty stomach or after food. Taking the medicine regularly at the right times increases its effectiveness. It is important to keep taking the medicine regularly until your doctor tells you it is safe to stop.

Use of this medicine may cause some common side effects such as increased appetite, weight gain, frequent urge to urinate, Cushing syndrome, cough, upper respiratory tract infection, abnormal hair growth, obesity, and nasopharyngitis. If any of these side effects bother you, let your doctor know.

Defza 18 Tablet can make it harder for you to fight off infections. Tell your doctor if you have any signs of infection such as a fever or sore throat. Before taking the medicine, you should let your doctor know of all the other medicines you are taking. Pregnant and breastfeeding women should consult their doctors before taking the medicine.

Uses of Defza Tablet

  • Duchenne muscular dystrophy(DMD)

Benefits of Defza Tablet

Duchenne muscular dystrophy(DMD)
Duchenne muscular dystrophy is a genetic condition that causes gradual muscle weakness, making everyday movements like walking, climbing stairs, and lifting objects increasingly difficult over time. Defza 18 Tablet helps reduce muscle inflammation and damage associated with this condition, which supports better preservation of muscle strength and function. With continued use, it can help slow disease progression, maintain mobility for a longer period, and support overall physical functioning and quality of life.

Side effects of Defza Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Defza
  • Increased appetite
  • Frequent urge to urinate
  • Cushing syndrome
  • Cough
  • Upper respiratory tract infection
  • Abnormal hair growth
  • Weight gain
  • Obesity
  • Nasopharyngitis (inflammation of the throat and nasal passages)

How to use Defza Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Defza 18 Tablet may be taken with or without food.
Avoid Defza 18 Tablet with salad and vegetable diet.

How Defza Tablet works

Defza 18 Tablet is a corticosteroid. It increases the level of glucocorticoid in the body and works by decreasing the formation of substances that cause inflammation and suppresses immunity to stop self damage to the body by the immune system (auto-immune reactions occurring in organ transplants or cancer).

All substitutes for Defza 18 Tablet

For information purposes only. Consult a doctor before taking any medicine.

Defcort 18 Tablet

by Macleods Pharmaceuticals Pvt Ltd
₹34/tablet
81% costlier
<h3 class=bodySemiBold>Defcort 18 Tablet</h3>

Orthocort 18mg Tablet

by Macleods Pharmaceuticals Pvt Ltd
₹34/tablet
81% costlier
<h3 class=bodySemiBold>Orthocort 18mg Tablet</h3>

Quick tips

  • Defza 18 Tablet helps treat inflammation, severe allergies, flare-ups of ongoing illnesses, and many other medical problems that require either reduction of inflammation or suppression of the immune system.
  • Do not use it more often or for longer than advised by your doctor.
  • Take it with food to avoid an upset stomach.
  • Defza 18 Tablet can make it harder for you to fight off infections. Notify your doctor if you have any signs of infection such as a fever or sore throat.
  • Side effects such as mood changes or stomach problems can happen when you start taking Defza 18 Tablet. Inform your doctor if this bothers you.
  • Do not stop taking Defza 18 Tablet suddenly without talking to your doctor first as it may worsen your symptoms.

Safety advice

Alcohol

Alcohol

CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with Defza 18 Tablet. Please consult your doctor.
Pregnancy

Pregnancy

CONSULT YOUR DOCTOR
The safety of Defza 18 Tablet during pregnancy has not been established. There are no adequate and well-controlled studies in pregnant women, and animal data on reproductive toxicity are insufficient. Your doctor will weigh the benefits and any potential risks before prescribing.
Breast feeding

Breast feeding

CONSULT YOUR DOCTOR
Defza 18 Tablet may be unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby. It should be used only if the expected benefit outweighs the potential risk. Please consult your doctor.
Driving

Driving

UNSAFE
Defza 18 Tablet may decrease alertness, affect your vision, or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
Kidney

Kidney

SAFE IF PRESCRIBED
Defza 18 Tablet is probably safe to use in patients with kidney disease. Limited data suggest dose adjustment may not be needed.
Liver

Liver

CONSULT YOUR DOCTOR
There is limited data available on the use of Defza 18 Tablet in patients with liver disease.

Interaction with drugs

Taking Defza with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
Life-threatening

Herpes Zoster / Shingles Vaccine (Recombinant, Adjuvanted) (Injection Route)

It is recommended to wait at least 3 months after discontinuing a high dose of Deflazacort before taking Herpes Zoster / Shingles Vaccine (Recombinant, Adjuvanted).
Severe

Cholera Vaccine (Inactivated) (Oral Route)

It is recommended to wait at least 3 months after discontinuing a high dose of Deflazacort before taking Cholera Vaccine (Inactivated).
Severe

Purified Vi Polysaccharide Typhoid Vaccine (Injection Route)

It is recommended to wait at least 3 months after discontinuing a high dose of Deflazacort before taking Purified Vi Polysaccharide Typhoid Vaccine.
Severe

Efavirenz (Oral Route)

Concomitant use may disturb the heart rhythm. Efavirenz may increase the metabolism of Deflazacort.
Moderate

Chloroquine (Oral Route)

Your doctor may monitor your potassium levels closely.

Frequently asked questions

Yes, Defza 18 Tablet is a steroid medicine also known as glucocorticoids which occur naturally in the body. These glucocorticoids help to maintain health and wellbeing. Defza 18 Tablet increases the corticosteroids levels in the body which helps in treating various illnesses involving inflammation (redness, tenderness, heat and swelling).
Defza 18 Tablet has anti-inflammatory and immunosuppressant properties. It is used for treating conditions like allergy diseases, anaphylaxis, asthma, rheumatoid arthritis, inflammatory skin diseases and autoimmune diseases (these diseases happen when your body’s immune system attacks the body itself and causes damage). The medicine also helps transplant patients as it suppresses the immune system so that the body does not reject the organ.
Defza 18 Tablet is a steroid medicine also known as glucocorticoids which occur naturally in the body. The medicine works by reducing the inflammation which helps in treating many illnesses caused due to active inflammation. Also, it stops the reactions known as autoimmune reactions which occur when your body's immune system attacks the body itself and causes damage.
Clinical studies have shown that Defza 18 Tablet has a similar effect as that of prednisone. Moreover, Defza 18 Tablet is better tolerated when used in the treatment of inflammatory conditions. However, consult your doctor for the right treatment of your condition.
No, Defza 18 Tablet is not a painkiller. It belongs to the class of medicines known as steroids.
Yes, Defza 18 Tablet can be taken with Tamsulosin. No harmful effects or any other interactions have been reported when they are used together.

Fact Box

Chemical Class

Gluco/mineralocorticoids, progestogin derivative

Habit Forming

No

Therapeutic Class

HORMONES

Action Class

Glucocorticoids

References

  1. Central Drugs Standard Control Organisation (CDSCO). [Accessed 03 Apr. 2019] (online) Available from:
  2. Deflazacort [Prescribing Information]. Northbrook, IL: Marathon Pharmaceuticals, LLC; 2017. [Accessed 20 Feb. 2024] (online) Available from:
  3. Deflazacort. New Brunswick, NJ: Ohm Laboratories Inc.; 2024. [Accessed 05 Jan. 2026] (online). Available from:
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User feedback

Once A Day
84%
Twice A Day
13%
Once A Week
3%
Rheumatic disorder
75%
Allergic conditions
25%
Average
67%
Poor
33%
No Side Effect
100%
With food
100%
Average
100%
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Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Wallace Pharmaceuticals Pvt Ltd
Address: Plot No. 100-105, Bethora Industrial Estate, Bethora, Ponda, Goa-403409 || 3rd Floor, Dempo Trade Centre Bldg., Patto Plaza, EDC Complex, Panaji 403001, Goa, India.

Vendor Details

Country of origin: India

Lab tests offered by us

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