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Defcort 12 Tablet

Deflazacort (12mg)

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Product Summary :

Defcort 12 Tablet contains deflazacort, a medicine used to treat Duchenne muscular dystrophy. It helps maintain muscle strength and slow the progression of muscle weakness. It is usually taken once daily, with or without food. Common side effects include weight gain, increased appetite, facial rounding, and cough. Regular monitoring of growth, bone health, blood pressure, and blood sugar is important during treatment.

Written By Dr. Subita Alagh, BDS,
Reviewed By Dr. Sachin Gupta, MD Pharmacology, MBBS,
Last updated on 17 Oct 2026 | 01:03 AM (IST)

₹141 MRP ₹151.887% off

The manufacturer has discontinued this product

(Inclusive of applicable taxes)

Gurgaon

Available in pack-size of 10 tablets

10 tablets pack-size available

Defcort 12 Tablet

₹259~~₹278.43~~

Available in pack size of 10 tablets

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Defcort 12 Tablet

strip of 6 tablets

₹141

~~₹151.88~~

Different pack-size

Defcort 12 Tablet

strip of 10 tablets

Deflazacort (12mg)

by Macleods Pharmaceuticals Pvt Ltd

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₹259

₹25.9 per tablet

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General Information

Contains

Deflazacort (12mg)

Marketer

Macleods Pharmaceuticals Pvt Ltd

Storage

Store below 25°C

The content is shown in English

Product introduction

Defcort 12 Tablet is a corticosteroid medicine used in Duchenne muscular dystrophy. It helps reduce muscle inflammation and damage, supporting muscle strength and slowing the progression of muscle weakness over time.

Defcort 12 Tablet can be taken with or without food. Taking the medicine regularly at the right times increases its effectiveness. It is important to keep taking the medicine regularly until your doctor tells you it is safe to stop.

Use of this medicine may cause some common side effects such as increased appetite, weight gain, frequent urge to urinate, cough, upper respiratory tract infection, hair growth, obesity, and nasopharyngitis. If any of these side effects bother you, let your doctor know.

Defcort 12 Tablet can make it harder for you to fight off infections. Tell your doctor if you have any signs of infection, such as a fever or sore throat. Before taking the medicine, you should let your doctor know of all the other medicines you are taking. Pregnant and breastfeeding women should consult their doctors before taking the medicine.

Uses of Defcort Tablet

Duchenne muscular dystrophy(DMD)

Benefits of Defcort Tablet

Duchenne muscular dystrophy(DMD)
Duchenne muscular dystrophy is a genetic condition that causes gradual muscle weakness, making everyday movements like walking, climbing stairs, and lifting objects increasingly difficult over time. Defcort 12 Tablet helps reduce muscle inflammation and damage associated with this condition, which supports better preservation of muscle strength and function. With continued use, it can help slow disease progression, maintain mobility for a longer period, and support overall physical functioning and quality of life.

Side effects of Defcort Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Defcort

Upper respiratory tract infection
Cough
Moon face (cushingoid)
Increased appetite
Pollakiuria
Central obesity
Weight gain
Excessive hair growth on face
Nasopharyngitis (inflammation of the throat and nasal passages)

How to use Defcort Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Defcort 12 Tablet may be taken with or without food.
Avoid Defcort 12 Tablet with salad and vegetable diet.

How Defcort Tablet works

Defcort 12 Tablet is a corticosteroid. It increases the level of glucocorticoid in the body and works by decreasing the formation of substances that cause inflammation and suppresses immunity to stop self damage to the body by the immune system (auto-immune reactions occurring in organ transplants or cancer).

Dosage

Defcort 12 Tablet is usually taken once daily, with or without food, as prescribed by your doctor. The dose is determined according to body weight, age, response to treatment, and other medicines being taken. Do not take Defcort 12 Tablet with grapefruit juice. Do not stop taking it suddenly, as the dose may need to be reduced gradually.

All substitutes for Defcort 12 Tablet

For information purposes only. Consult a doctor before taking any medicine.

Quick tips

Defcort 12 Tablet helps treat inflammation, severe allergies, flare-ups of ongoing illnesses, and many other medical problems that require either reduction of inflammation or suppression of the immune system.
Do not use it more often or for longer than advised by your doctor.
Defcort 12 Tablet can make it harder for you to fight off infections. Notify your doctor if you have any signs of infection such as a fever or sore throat.
Side effects such as mood changes or stomach problems can happen when you start taking Defcort 12 Tablet. Inform your doctor if this bothers you.
Do not stop taking Defcort 12 Tablet suddenly without talking to your doctor first as it may worsen your symptoms.

Safety advice

Alcohol

CONSULT YOUR DOCTOR

It is not known whether it is safe to consume alcohol with Defcort 12 Tablet. Please consult your doctor.

Pregnancy

CONSULT YOUR DOCTOR

The safety of Defcort 12 Tablet during pregnancy has not been established. There are no adequate and well-controlled studies in pregnant women, and animal data on reproductive toxicity are insufficient. Your doctor will weigh the benefits and any potential risks before prescribing.

Breast feeding

CONSULT YOUR DOCTOR

Defcort 12 Tablet may be unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby. It should be used only if the expected benefit outweighs the potential risk. Please consult your doctor.

Driving

CONSULT YOUR DOCTOR

It is not known whether Defcort 12 Tablet alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react. Please consult your doctor.

Kidney

SAFE IF PRESCRIBED

Defcort 12 Tablet is probably safe to use in patients with kidney disease. Limited data suggest dose adjustment may not be needed.

Liver

CAUTION

Defcort 12 Tablet should be used with caution in patients with liver disease. Dose adjustment may be needed.

Interaction with drugs

Taking Defcort with any of the following medicines can modify the effect of either of them and cause some undesirable side effects

Life-threatening

Herpes Zoster / Shingles Vaccine (Recombinant, Adjuvanted) (Injection Route)

It is recommended to wait at least 3 months after discontinuing a high dose of Deflazacort before taking Herpes Zoster / Shingles Vaccine (Recombinant, Adjuvanted).

Severe

Cholera Vaccine (Inactivated) (Oral Route)

It is recommended to wait at least 3 months after discontinuing a high dose of Deflazacort before taking Cholera Vaccine (Inactivated).

Severe

Purified Vi Polysaccharide Typhoid Vaccine (Injection Route)

It is recommended to wait at least 3 months after discontinuing a high dose of Deflazacort before taking Purified Vi Polysaccharide Typhoid Vaccine.

Severe

Efavirenz (Oral Route)

Concomitant use may disturb the heart rhythm. Efavirenz may increase the metabolism of Deflazacort.

Moderate

Chloroquine (Oral Route)

Your doctor may monitor your potassium levels closely.

Frequently asked questions

Is Defcort 12 Tablet a steroid?

Yes, Defcort 12 Tablet is a steroid medicine also known as glucocorticoids which occur naturally in the body. These glucocorticoids help to maintain health and wellbeing. Defcort 12 Tablet increases the corticosteroids levels in the body which helps in treating various illnesses involving inflammation (redness, tenderness, heat and swelling).

In what conditions should I avoid giving Defcort 12 Tablet to my child?

Avoid giving Defcort 12 Tablet to your child if they have conditions like cardiac disease or congestive heart failure (except in the presence of active rheumatic carditis), hypertension, thromboembolic disorders, or diabetes mellitus. Defcort 12 Tablet should also be avoided if your child has a family history of active TB, active herpes infection, osteoporosis, myasthenia gravis, or renal insufficiency.

What do I need to know about Defcort 12 Tablet and my child’s immunizations?

For certain vaccines (live or live-attenuated vaccines), your child will need to wait 4 to 6 weeks before starting Defcort 12 Tablet. Hence, your child needs to receive all immunizations according to immunization guidelines before they start taking Defcort 12 Tablet.

My child is suffering from a seizure disorder. Is it safe to give Defcort 12 Tablet to my child?

Prolonged intake of Defcort 12 Tablet can lead to mental illness as well as a seizure disorder. Therefore, any child who is already suffering from seizure disorder should not take Defcort 12 Tablet.

Fact Box

Chemical Class

Gluco/mineralocorticoids, progestogin derivative

Habit Forming

Therapeutic Class

HORMONES

Action Class

Glucocorticoids

References

100% genuine products

Safe & secure payments

No contact delivery

Fully sanitized facilities

User feedback

Patients taking Defcort 12 Tablet

Once A Day

100%

What are you using Defcort Tablet for?

Severe allergic reactions

31%

Allergic conditions

25%

Asthma

15%

Others

15%

Rheumatic disorder

10%

How much was the improvement?

Excellent

46%

Poor

28%

Average

26%

What were the side-effects while using Defcort 12 Tablet?

No Side Effect

33%

Weight gain

17%

Facial swelling

17%

Increased appetite

17%

Redistribution/accumulation of body fat

17%

How do you take Defcort Tablet?

With food

90%

With or without food

10%

Please rate Defcort 12 Tablet on price

Average

53%

Expensive

40%

Not Expensive

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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Macleods Pharmaceuticals Pvt Ltd
Address: Atlanta Arcade, Marol Church Road, Andheri (East), Mumbai - 400059, INDIA.

Vendor Details

Country of origin: India

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Defcort 12 Tablet

Defcort 12 Tablet

Product Summary :

Save more with additional offers

General Information

Contains

Marketer

Storage

Product introduction

Uses of Defcort Tablet

Benefits of Defcort Tablet

Side effects of Defcort Tablet

How to use Defcort Tablet

How Defcort Tablet works

Dosage

All substitutes for Defcort 12 Tablet

Defcicot 12 Tablet

Cortimax 12mg Tablet

Defza 12mg Tablet

Samliza 12 Tablet

Orthocort 12mg Tablet

Quick tips

Safety advice

Alcohol

Pregnancy

Breast feeding

Driving

Kidney

Liver

Interaction with drugs

Herpes Zoster / Shingles Vaccine (Recombinant, Adjuvanted) (Injection Route)

Cholera Vaccine (Inactivated) (Oral Route)

Purified Vi Polysaccharide Typhoid Vaccine (Injection Route)

Efavirenz (Oral Route)

Chloroquine (Oral Route)

Frequently asked questions

Is Defcort 12 Tablet a steroid?

In what conditions should I avoid giving Defcort 12 Tablet to my child?

What do I need to know about Defcort 12 Tablet and my child’s immunizations?

My child is suffering from a seizure disorder. Is it safe to give Defcort 12 Tablet to my child?

Fact Box

Chemical Class

Habit Forming

Therapeutic Class

Action Class

References

User feedback

Patients taking Defcort 12 Tablet

What are you using Defcort Tablet for?

How much was the improvement?

What were the side-effects while using Defcort 12 Tablet?

How do you take Defcort Tablet?

Please rate Defcort 12 Tablet on price

Want to know more

Have issue with the content

Disclaimer

Marketer details

Vendor Details

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