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Darzalex Injection

Daratumumab (100mg)

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Product Summary :

Darzalex Injection contains daratumumab, a medicine used to treat multiple myeloma and light chain (AL) amyloidosis. It works by acting on abnormal plasma cells and helping the immune system destroy them. It is given by a doctor, alone or with other medicines depending on the condition. Common side effects include infections, diarrhea, fatigue, nausea, constipation, and swelling. Regular blood tests and medical monitoring are required during treatment.

Written By Dr. Subita Alagh, BDS,
Reviewed By Dr. Rajeev Sharma, MBA, MBBS,
Last updated on 18 Oct 2026 | 01:03 AM (IST)

₹17008 MRP ₹1890010% off

(Inclusive of applicable taxes)

Gurgaon

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General Information

Contains

Daratumumab (100mg)

Marketer

Janssen Pharmaceuticals

Storage

Store below 30°C

The content is shown in English

Product introduction

Darzalex Injection is a medicine used to treat multiple myeloma, a type of blood cancer, and light chain (AL) amyloidosis, a condition that can damage organs such as the heart and kidneys. It works by targeting abnormal cells responsible for these conditions.

Darzalex Injection is given under the supervision of a doctor. Your doctor will decide what dose is necessary and how often you need to take it. The dosage will depend on what you are being treated for and may change from time to time. You should take it exactly as your doctor has advised.

Infusion reaction such as swollen face, lips, mouth, tongue or throat, difficulty swallowing or breathing are very common side effects. This medicine may reduce the number of blood cells (decrease white blood cells) in your blood, which may increase your susceptibility to infections. Regular blood tests are required to check your blood cells while taking this medicine.

Many other medicines can affect, or be affected by, this medicine, so let your doctor know all medications you are using. This medicine is not recommended during pregnancy or while breastfeeding. Use of effective contraception by both males and females during treatment is important to avoid pregnancy.

There is a Patient Support Program/Patient Assistance Program available in India for this medicine, being managed by Tata 1mg. Please contact your prescribing doctor to know more about the same. You may also call on (1800-102-1618) for more details.

Uses of Darzalex Injection

Treatment of Multiple myeloma : Used to treat a type of blood cancer and a disease that has returned or has not responded to previous treatments.
Light chain (AL) Amyloidosis

Benefits of Darzalex Injection

Treatment of Multiple myeloma
Multiple myeloma is a type of blood cancer that affects plasma cells in the bone marrow, leading to weak bones, anemia, kidney problems, and frequent infections. Darzalex Injection helps control the growth of these cancerous cells, improving symptoms and slowing disease progression.

Light chain (AL) Amyloidosis
Light chain (AL) amyloidosis occurs when proteins accumulate in organs such as the heart, kidneys, and liver, affecting their ability to function properly. Darzalex Injection helps control the underlying disease and reduces the risk of further organ damage and disease progression.

Side effects of Darzalex Injection

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Darzalex

Upper respiratory tract infection
Constipation
Anemia (low number of red blood cells)
Neuropathy
Fatigue
Fever

How to use Darzalex Injection

Your doctor or nurse will give you this medicine. Kindly do not self administer.

How Darzalex Injection works

Darzalex Injection is a monoclonal antibody that recognizes and attaches to specific proteins on the surface of cancer cells. It supports your immune system against cancer.

Dosage

Darzalex Injection is given as an injection by a doctor. Treatment usually begins with weekly injections, followed by injections every 2 weeks and eventually every 4 weeks. However, the schedule may vary depending on the condition being treated and the other medicines prescribed. Your doctor will determine the appropriate dose, frequency, and duration of treatment.

Quick tips

To reduce nausea, take anti-nausea medications as prescribed by your doctor, and eat small, frequent meals.
Do not receive any kind of immunization or vaccination without your doctor's approval while taking Darzalex Injection.
Use contraceptives, and avoid getting pregnant while taking Darzalex Injection. Barrier methods of contraception, such as condoms, should be used during treatment and for 3 months after the last dose of Darzalex Injection.
Before receiving Darzalex Injection inform your doctor if you have a history of breathing problems or hepatitis B infection.
Let your doctor know if you are pregnant or plan to become pregnant or breastfeeding.

Safety advice

Alcohol

CONSULT YOUR DOCTOR

It is not known whether it is safe to consume alcohol with Darzalex Injection. Please consult your doctor.

Pregnancy

UNSAFE

Darzalex Injection is highly unsafe during pregnancy. It can cause serious harm to the unborn baby, including birth defects and pregnancy loss. Do not use this medicine if you are pregnant or planning to become pregnant.

Breast feeding

CONSULT YOUR DOCTOR

Darzalex Injection may be unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby. It should be used only if the expected benefit outweighs the potential risk. Please consult your doctor.

Driving

CONSULT YOUR DOCTOR

It is not known whether Darzalex Injection alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react. Please consult your doctor.

Kidney

CONSULT YOUR DOCTOR

There is limited data available on the use of Darzalex Injection in patients with kidney disease. Please consult your doctor.

Liver

CONSULT YOUR DOCTOR

There is limited data available on the use of Darzalex Injection in patients with liver disease.

Frequently asked questions

What are the most important infusion-related warnings of Darzalex Injection?

Can Darzalex Injection affect blood transfusions or blood tests?

Yes, Darzalex Injection can cause a positive indirect Coombs test and interfere with matching blood for transfusions for up to six months after the last dose, so a blood type and screen is done before starting this medicine, and blood banks must be informed about current or recent treatment.

Does Darzalex Injection lower blood counts?

Darzalex Injection can reduce white blood cells (raising infection risk) and platelets (raising bleeding risk), so regular blood tests are done, and dosing may be delayed until counts recover when needed.

Can hepatitis B reactivate with Darzalex Injection?

Yes, hepatitis B can reactivate with Darzalex Injection, rarely causing severe illness. Doctors check hepatitis B status before, during, and after treatment and monitor for symptoms such as worsening tiredness or yellowing of eyes/skin.

Does Darzalex Injection change how doctors measure myeloma response?

Yes, Darzalex Injection can appear on serum protein tests (SPEP/IFE) and look like the myeloma protein, potentially masking a complete response. Specialized assays may be used to distinguish the medicine from the disease protein when needed.

Are there special cautions for breathing or eye symptoms during receiving Darzalex Injection?

People with chronic lung disease may need extra inhaled medicines in addition to receiving Darzalex Injection. Additionally, any new eye pain, blurred vision, or acute vision changes during receiving Darzalex Injection should trigger an immediate pause and urgent eye evaluation before restarting.

What should be done before starting Darzalex Injection treatment to improve safety?

Before starting Darzalex Injection, your doctor will check your blood type and hepatitis B status, plan medicines to prevent infusion reactions, and arrange regular blood count monitoring. You should also inform your doctor about any past infections, lung problems, and all medicines or supplements you’re taking.

Fact Box

Chemical Class

Peptides

Habit Forming

Therapeutic Class

ANTI NEOPLASTICS

Related lab tests

Albumin/Globulin Ratio, Serum

Calcium

Complete Blood Count

Kidney Function Test

References

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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Janssen Pharmaceuticals
Address: Johnson & Johnson Private Limited., 501 Arena Space, Behind Majas Bus Depot, Off Jogeshwari Vikhroli Link Road, Jogeshwari (E), Mumbai 400 060

Vendor Details

Country of origin: United kingdom

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Darzalex Injection

Darzalex Injection

Product Summary :

Save more with additional offers

General Information

Contains

Marketer

Storage

Product introduction

Uses of Darzalex Injection

Benefits of Darzalex Injection

Side effects of Darzalex Injection

How to use Darzalex Injection

How Darzalex Injection works

Dosage

Quick tips

Safety advice

Alcohol

Pregnancy

Breast feeding

Driving

Kidney

Liver

Frequently asked questions

What are the most important infusion-related warnings of Darzalex Injection?

Can Darzalex Injection affect blood transfusions or blood tests?

Does Darzalex Injection lower blood counts?

Can hepatitis B reactivate with Darzalex Injection?

Does Darzalex Injection change how doctors measure myeloma response?

Are there special cautions for breathing or eye symptoms during receiving Darzalex Injection?

What should be done before starting Darzalex Injection treatment to improve safety?

Fact Box

Chemical Class

Habit Forming

Therapeutic Class

Related lab tests

Albumin/Globulin Ratio, Serum

Calcium

Complete Blood Count

Kidney Function Test

References

Want to know more

Have issue with the content

Disclaimer

Marketer details

Vendor Details

Lab tests offered by us

Related/Popular tests