Dargen 40 Injection
Prescription Required
Product introduction
Dargen 40 Injection is used in the treatment of anemia that may have occurred due to chronic kidney disease or chemotherapy. It works by stimulating the bone marrow to produce more red blood cells.
Dargen 40 Injection is a medicine that needs to be used with utmost care because it can lead to serious side effects. It is important that you seek treatment from a doctor who is experienced in providing this medical therapy. You should follow all the directions of the doctor strictly. It is given under the supervision of a healthcare professional.
Common side effects include abdominal pain, high blood pressure, rash, injection site pain, breathlessness, cough, and peripheral edema. Inform your doctor if there are symptoms of very high blood pressure, such as severe headache, problems with your eyesight, nausea, vomiting, or fits (seizures).
Your doctor may get your blood tests done regularly to monitor the levels of salts (electrolytes such as potassium), hemoglobin, and blood cells in your blood. You should stop taking it and consult with a doctor if you develop shortness of breath or a skin rash.
Before taking Dargen 40 Injection, tell your doctor if you have heart disease, high blood pressure, or have had a seizure or stroke. If you are pregnant or breastfeeding, or plan to become pregnant, consult your doctor to make sure it is safe for you.
Uses of Dargen Injection
Benefits of Dargen Injection
In Treatment of Anemia due to cancer chemotherapy
In patients undergoing cancer chemotherapy, Dargen 40 Injection helps manage anemia by promoting red blood cell production, which may be suppressed due to the effects of chemotherapy on the bone marrow. This reduces the need for blood transfusions and alleviates symptoms such as weakness and tiredness. This way it makes the patients feel more energetic and better able to cope with their cancer treatment and daily routines.
In Treatment of Anemia due to chronic kidney disease
Dargen 40 Injection is an effective treatment for anemia caused by chronic kidney disease (CKD). It stimulates the bone marrow to produce more red blood cells, compensating for the reduced erythropoietin production in damaged kidneys. Increasing hemoglobin levels helps relieve symptoms like fatigue, dizziness, and shortness of breath associated with anemia. Improvement in red blood cell count also increases energy levels and physical function, allowing individuals with CKD to engage more comfortably in daily activities and enjoy a better quality of life.
Side effects of Dargen Injection
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Dargen
- Abdominal pain
- High blood pressure
- Rash
- Injection site pain
- Breathlessness
- Cough
- Peripheral edema
- Procedural hypotension (low blood pressure)
- Convulsion
- Thromboembolism
- Angina (heart related chest pain)
How to use Dargen Injection
Your doctor or nurse will give you this medicine. Kindly do not self administer.
How Dargen Injection works
Dargen 40 Injection is an erythropoiesis-stimulating agent (ESA). It works by stimulating the bone marrow (soft tissue inside the bones which produces red blood cells) to produce more red blood cells.
Safety advice
Alcohol
CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with Dargen 40 Injection. Please consult your doctor.
Pregnancy
CONSULT YOUR DOCTOR
Dargen 40 Injection may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Breast feeding
CONSULT YOUR DOCTOR
Information regarding the use of Dargen 40 Injection during breastfeeding is not available. Please consult your doctor.
Driving
SAFE
Dargen 40 Injection does not usually affect your ability to drive.
Kidney
SAFE IF PRESCRIBED
Dargen 40 Injection is safe to use in patients with kidney disease. No dose adjustment of Dargen 40 Injection is recommended.
Liver
CAUTION
Dargen 40 Injection should be used with caution in patients with liver disease. Dose adjustment of Dargen 40 Injection may be needed. Please consult your doctor.
What if you forget to take Dargen Injection?
If you miss a dose of Dargen 40 Injection, consult your doctor.
All substitutes
For informational purposes only. Consult a doctor before taking any medicines.
Dargen 40 Injection
₹2969/Injection
Cresp 40 Injection
Dr Reddy's Laboratories Ltd
₹3653.25/injection
20% costlier
Bionesp 40 Injection
Eris Lifesciences Ltd
₹3446/injection
14% costlier
Actorise 40 Injection
Cipla Ltd
₹2928.2/injection
3% cheaper
Darbelife 40mcg Pfs Injection
Hetero Drugs Ltd
₹3030/injection
same price
Darbosis 40 Injection
Micro Labs Ltd
₹2865/injection
6% cheaper
Quick tips
- Dargen 40 Injection helps in the treatment of anemia that may have occurred due to chronic kidney disease or cancer chemotherapy.
- It is given as a single injection under your skin; additionally, it can be given intravenously.
- Your doctor may get your blood tests done regularly to monitor the levels of hemoglobin in your blood.
- Stop taking Dargen 40 Injection and inform your doctor if you develop shortness of breath or a skin rash.
Fact Box
Chemical Class
Amino Acids, Peptides Analogues
Habit Forming
No
Therapeutic Class
BLOOD RELATED
Action Class
Erythropoiesis-Stimulating Agents (ESAs)
Interaction with drugs
Taking Dargen with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
If concurrent use is essential, watch out for symptoms such as unusual bleeding, swelling in one leg or arm, new or worsening chest pain or sudden shortness of breath and consult y
If concurrent use is essential, your doctor may monitor your potassium levels along with your overall treatment and adjust the doses as per the observations.
Concurrent use may in
If concurrent use is essential, watch out for symptoms such as fatigue, shortness of breath, unusual paleness, easy bruising or bleeding and consult your doctor if you experience t
If concurrent use is essential, your doctor may monitor your treatment and adjust the doses as per the observations.
Concurrent use may increase the risk of blood clots.
Your doctor may regularly monitor your blood pressure and potassium levels during the simultaneous use of these medicines. Olmesartan Medoxomil may reduce efficacy of Darbepoetin a
Patient concerns
User feedback
Patients taking Dargen 40 Injection
Once A Week
80%
Once A Month
20%
What are you using Dargen Injection for?
Anemia due to*
89%
Others
7%
Anemia
4%
*Anemia due to chronic kidney disease
How much was the improvement?
Average
49%
Poor
31%
Excellent
20%
What were the side-effects while using Dargen 40 Injection?
No Side Effec*
80%
High blood pr*
10%
Hypersensitiv*
10%
*No Side Effect, High blood pressure, Hypersensitivity
How do you take Dargen Injection?
With food
50%
With or witho*
40%
Empty stomach
10%
*With or without food
Please rate Dargen 40 Injection on price
Expensive
100%
FAQs
How long does it take for Dargen 40 Injection to start working?
You will be able to notice an increase in the count of red blood cells (hemoglobin levels) in 2-6 weeks of starting Dargen 40 Injection. If you have any other concerns, consult your doctor.
Is Dargen 40 Injection safe to use?
Dargen 40 Injection is a medicine that needs to be used with utmost care because it can lead to serious side effects and even death of the patient. It is important that you seek treatment from a doctor who is experienced in providing Dargen 40 Injection therapy. Follow all the directions strictly.
Other than pure red cell aplasia (PRCA), can there be other reasons for not responding to Dargen 40 Injection?
You may not respond to Dargen 40 Injection if you have deficiencies of iron, folic acid, or vitamin B12. It is important that you take measures to correct these deficiencies. Other reasons behind not responding to the treatment could be bleeding, infections, inflammation, and bone marrow fibrosis. Therefore, consult our doctor regarding the same.
Can Dargen 40 Injection be used in children?
Yes, Dargen 40 Injection is used to treat anemia due to chronic kidney disease in children who are above 1 year of age. The effectiveness of Dargen 40 Injection and side effects seen in children are similar to adults. However, consult your doctor if you are not sure.
Can Dargen 40 Injection affect blood pressure?
Yes, Dargen 40 Injection can affect blood pressure. During initial therapy with Dargen 40 Injection, blood pressure should be monitored and those who have high blood pressure should take appropriate measures to control blood pressure. Your doctor may stop Dargen 40 Injection if the blood pressure remains uncontrolled.
Who should not take Dargen 40 Injection?
Individuals who have cancer but have not been prescribed Dargen 40 Injection by the doctor should not take it. Additionally, patients with uncontrolled hypertension (high blood pressure), patients with a history of anemia called pure red cell aplasia (PRCA) that starts after treatment with Dargen 40 Injection or other erythropoietin medicines, and patients with a history of serious allergic reaction to this medicine should not take this medicine.
Want to share the information?
Disclaimer:
Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.References
- Kaushansky K, Kipps TJ. Hematopoietic Agents: Growth Factors, Minerals, and Vitamins. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. pp. 1071-72.
- Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 358-59.
- Darbepoetin alfa. Milton Road, Cambridge: Amgen Ltd.; 2001 [revised Sep. 2017]. [Accessed 23 Jan. 2019] (online) Available from:
- Darbepoetin alfa. Thousand Oaks, CA: Amgen Inc.; 2001. [Accessed 07 Apr. 2019] (online) Available from:
- Drugs and Lactation Database (LactMed®) [Internet]. Bethesda (MD): National Institute of Child Health and Human Development; 2006. Darbepoetin. [Accessed 17 Jun. 2023] (online) Available from:
- Darbepoetin alfa [Prescribing Information]. Thousand Oaks, California: Amgen Inc.; 2019. [Accessed 17 Jun. 2023] (online) Available from:
- Aranesp Injection (Darbepoetin alfa) [Product Information]. [Accessed 17 Jun. 2023] (online) Available from:
Marketer details
Name: Lupin Ltd
Address: 3rd floor Kalpataru Inspire, Off. W E Highway, Santacruz (East), Mumbai 400 055. India
Country of origin: India
Expires on or after: April, 2027
A licensed vendor partner from your nearest location will deliver Dargen 40 Injection. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's ℞ and the availability of this medicine.
Phone Number: 0124-4166666
Address: 5th Floor Tower - B of the Presidency Building, 46/4 Mehrauli Gurgaon Road, Sector 14, Gurugram, Haryana-122001, India
Expires on or after: April, 2027
A licensed vendor partner from your nearest location will deliver Dargen 40 Injection. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's ℞ and the availability of this medicine.
In case of any issues, contact us
Email ID: [email protected]Phone Number: 0124-4166666
Address: 5th Floor Tower - B of the Presidency Building, 46/4 Mehrauli Gurgaon Road, Sector 14, Gurugram, Haryana-122001, India
Lab tests offered by us
Related/Popular tests
₹2523.65₹3033.15Get 17% OFF
₹2539+ free shipping with
Inclusive of all taxes
This offer price is valid on orders above ₹2000. Apply coupon HEALTHALL on the cart. Max. coupon discount is ₹530. T&C apply.
0.4 ml in 1 prefilled syringe
Cash on delivery available
Not returnable Read policy
Get by Tomorrow
Delivering to: