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Cycrame 200mg Injection

Prescription Required

Overview

Introduction

Cycrame 200mg Injection is used in the treatment of different kinds of cancers. It is also used to treat kidney disease known as nephrotic syndrome in children after other treatments have not worked. It may be also used to treat other conditions, as determined by the doctor.

Cycrame 200mg Injection is given as an injection into a vein by the healthcare professional, but better if injected at the same time every day. Your doctor will decide what dose is necessary and how often you need to take it. This will depend on what you are being treated for and may change from time to time. You should take it exactly as your doctor has advised. Taking it in the wrong way or taking too much can cause very serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to.

The most common side effects of this medicine include vomiting, nausea, hair loss, fever, and blood in urine. If they do not go away or get worse, tell your doctor. There may be ways of preventing or reducing these effects. It is very strong medicine and some people may develop serious side effects while taking it. This medicine may lower your ability to fight infections and lead to problems with your blood, liver or kidneys. Your doctor will advise you regular blood tests to check for these. It is advised that you drink extra fluids so that you pass more urine. This will help prevent bladder and kidney problems and keep your kidneys working well.

Before taking it, tell your doctor if you have liver, or kidney problems or are taking any medicines to treat infections. Many other medicines can affect, or be affected by, this medicine so let your doctor know all medications you are using. This medicine is not recommended during pregnancy or while breastfeeding. The use of effective contraception by both males and females during treatment is important to avoid pregnancy.

Uses of Cycrame Powder for Injection

Side effects of Cycrame Powder for Injection

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Cycrame

  • Vomiting
  • Nausea
  • Hair loss
  • Fever
  • Blood in urine
  • Diarrhea
  • Decreased white blood cell count (neutrophils)

How to cope with side effects?

The occurrence of side effects varies from person to person. The following are a few ways of dealing with some of the common side effects. However, consult your doctor if these persist.

  • Coping with Vomiting
    You can help yourself by eating small, frequent meals rather than large ones and drinking plenty of fluids. Eat slowly. Avoid fatty, fried, spicy and very sweet foods. Eat cold or slightly warm food if the smell of cooked or cooking food makes you feel sick. Get plenty of fresh air. You could also try chewing ginger or drinking ginger tea. Eat bananas to replace potassium in your blood which can drop if you are sick (vomit). Use oral rehydration salts to replace vitamins and minerals lost through being sick. There are some medicines that can help you stop feeling sick. Speak to your doctor if your condition does not improve.
  • Coping with Nausea
    You can help yourself by eating small, frequent meals rather than large ones and drinking plenty of fluids. Eat slowly. Avoid fatty, fried, spicy and very sweet foods. Eat cold or slightly warm food if the smell of cooked or cooking food makes you feel sick. Get plenty of fresh air. You could also try chewing ginger or drinking ginger tea. Eat bananas to replace potassium in your blood which can drop if you are sick (vomit). Use oral rehydration salts to replace vitamins and minerals lost through being sick. There are some medicines that can help you stop from feeling sick. Speak to your doctor if your condition does not improve.
  • Coping with Hair loss
    Use gentle hair products such as baby shampoo. Use a soft brush and comb gently. Avoid using hairdryers, curling tongs or hair straighteners and pat your hair dry after washing. Do not color your hair. Protect your scalp by covering your head in the sun. It is necessary to not take the stress and eat a balanced, nutritious diet as it is vital for the health of your hair.
  • Coping with Blood in urine
    If you notice any blood in your urine, contact your doctor. It might be a symptom of something more serious. Your doctor will probably want you to get follow-up tests and advise you accordingly. Meanwhile, drink plenty of fluids. This will dilute your urine and make it easier to pass.
  • Coping with Diarrhea
    Keep up your intake of fluids and electrolytes (sugars and salts) to avoid getting dehydrated. Eat less fiber (avoid raw fruits, fruit juice and vegetables). Talk to your doctor about possible medication to manage diarrhea. Ask about reducing the dosage of your drug or other suitable treatments.
  • Coping with Decreased white blood cell count (neutrophils)
    If you have a low level of white blood cells, you are more likely to get infections. There are several ways to reduce your chances of catching or spreading an infection. Avoid unnecessary exposure to germs when you can. Wash your hands frequently and thoroughly with soap or use a sanitiser. Avoid crowds and avoid contact with people who are ill or have infections. Use disposable tissues for coughs and sneezes. Consider using an appropriate face mask. Do not share personal items like cutlery, glasses, towels or toothbrushes with others. Get enough rest and eat a well balanced healthy diet.

How to use Cycrame Powder for Injection

Your doctor or nurse will give you this medicine. Kindly do not self administer.

How Cycrame Powder for Injection works

Cycrame 200mg Injection is an anti-cancer medication. It is an alkylating agent which works by damaging the genetic material (DNA and RNA) of the cancer cells, thereby stopping their growth and multiplication. This is how it works against cancer.

Safety Advice

Alcohol
UNSAFE
It is unsafe to consume alcohol with Cycrame 200mg Injection.
Pregnancy
CONSULT YOUR DOCTOR
Cycrame 200mg Injection is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.
Breastfeeding
UNSAFE
Cycrame 200mg Injection is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.
Driving
UNSAFE
Cycrame 200mg Injection may cause side effects which could affect your ability to drive.
Cycrame 200mg Injection may cause undesirable effects (e.g., dizziness, blurred vision, visual impairment) which could affect the ability to drive.
Kidney
CAUTION
Cycrame 200mg Injection should be used with caution in patients with severe kidney disease. Dose adjustment of Cycrame 200mg Injection may be needed. Please consult your doctor.
Liver
CAUTION
Cycrame 200mg Injection should be used with caution in patients with liver disease. Dose adjustment of Cycrame 200mg Injection may be needed. Please consult your doctor.

Alternate Brands

For informational purposes only. Consult a doctor before taking any medicines.
No alternate brands found for this medicine

Quick Tips

  • Cycrame 200mg Injection helps in the treatment of cancer.
  • It is injected into the vein by a doctor or healthcare professional.
  • Drink plenty of fluids or urinate frequently to prevent urinary problems while taking this medication.
  • Your doctor may get regular blood tests to monitor your blood counts while on treatment with this medication.
  • You are more likely to get sick or heal slower while taking this medication. Talk to your doctor before getting any vaccines.
  • Contact your doctor immediately if you experience difficulty in urinating or blood in urine while on treatment with this medication.
  • Do not take Cycrame 200mg Injection if you are pregnant or breastfeeding.
  • Use effective contraception method to prevent pregnancy while taking this medicine.

Fact Box

Chemical Class
Nitrogen Mustard Compounds
Habit Forming
No

Interaction with Drugs

Taking Cycrame with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
Brand(s): Clowil, Odis, Kamestin
SERIOUS
Brand(s): Cardisip, Digover, Caxin
SERIOUS
Brand(s): Imorab, Equirab, Carig
SERIOUS
Brand(s): Fungis
SERIOUS

Patient Concerns

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Nephrotic syndrome since December 2009
Dr. Vikas Sharma
Neurology
Show to kidney
nephrotic syndrome protein in urine
Dr. Deepak Kumar Soni
Ayurveda
Hi Kindly consult to your nearest Ayurvedic doctor Need to take proper treatment
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Do you have any questions related to Cycrame 200mg Injection ?

FAQs

Q. Can Cycrame cause infertility?

Yes, Cycrame can cause infertility in both men and women. It may interfere with the normal menstrual cycle in women and may stop sperm production in men. If you are considering becoming parents after the treatment please discuss this with your doctor. Talk to your doctor about cryopreservation (freezing) of sperm or eggs prior to treatment because of the possibility of irreversible infertility due to therapy with Cycrame.

Q. Do I need to avoid sun exposure during treatment with Cycrame?

No, there is no evidence that you need to avoid sun exposure while on Cycrame. Skin and nail discoloration are reported rarely with Cycrame.

Q. Can Cycrame cause cancer?

Cancer medicines and radiation therapy can increase the risk of developing other cancers. These may not develop soon and may take a number of years after the completion of your treatment. The risk of developing cancer with Cycrame is high in the urinary bladder. Other rare cancers that may occur with use of Cycrame include Acute leukemia, Myelodysplastic syndrome, and cancer of the ureters.

Q. Is Cycrame chemotherapy medicine?

Yes, Cycrame is a chemotherapy medicine, it belongs to the class of alkylating agents. It works by killing cancer cells. It is also known as cytotoxic medicine.

Q. Can Cycrame be used for non-cancer condition?

Yes, Cycrame can be used to treat nephrotic syndrome (a disease that is caused by damage to the kidneys) in children whose disease has not improved, has gotten worse, or has come back after taking other medications. Along with that, it can be used in children who experienced intolerable side effects with other medications. However, in adults, the safety and effectiveness of Cycrame for nephrotic syndrome has not been established.

Q. Can Cycrame causes weight loss?

Yes, Cycrame may cause weight loss because of reduced appetite. This reduction in weight could be due to underlying cancer. Consult your doctor, if weight loss is worrying you.

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Disclaimer:

1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover all possible side effects, drug interactions or warnings or alerts. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

References

  1. Lake DF, Briggs AD, Akporiaye ET. Immunopharmacology. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. p. 975.
  2. Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 335-38.
  3. Cyclophosphamide monohydrate. Camberley, Surrey: Sandoz Limited; 2014 [revised 07 Jun. 2017]. [Accessed 26 Mar. 2019] (online) Available from:External Link
  4. Cyclophosphamide. Baxter Health Corporation; 1959. [Accessed 26 Mar. 2019] (online) Available from:External Link
  5. Chaves RG, Lamounier JA. Breastfeeding and maternal medications. J Pediatr (Rio J). 2004;80(5 Suppl):S189-S198. [Accessed 26 Mar. 2019] (online) Available from:External Link

Manufacturer/Marketer Address

213, Shivai Dongre Industrial Premises, Andheri - Kurla Road, Andheri(E), Mumbai - 400 072, Maharashtra, India.
A licensed vendor partner from your nearest location will deliver Cycrame 200mg Injection. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's ℞ and the availability of this medicine.
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