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Cresadex 20 Plus Tablet is a combination of two medicines used to treat high cholesterol. It helps reduce "bad" cholesterol (LDL) and triglycerides (fats) levels. It also helps to reduce the risk of future heart attack and stroke.

Written By Dr. Sakshi Jain, MS, BDS,
Reviewed By Dr. Sachin Gupta, MD Pharmacology, MBBS,
Last updated on 21 Jan 2026 | 03:26 PM (IST)
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Cresadex 20 Plus Tablet
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Cresadex 20 Plus Tablet image
Cresadex 20 Plus Tablet image
Cresadex 20 Plus Tablet image
Cresadex 20 Plus Tablet image
Cresadex 20 Plus Tablet image
Cresadex 20 Plus Tablet image

Product introduction

Cresadex 20 Plus Tablet can be taken with or without food. You should take it regularly at evenly spaced intervals as per the schedule prescribed by your doctor. Taking it at the same time every day will help you remember to take it. The dose and duration of treatment will depend on what you are being treated for. Do not stop taking it until you have finished the complete course, even when you feel better. You can help this medicine work better by making a few changes to your lifestyle, such as keeping active, stopping smoking, eating a healthy, low-fat diet, and exercising regularly.


Headache, weakness, muscle pain, and back pain are some common side effects of this medicine. These are usually mild, but let your doctor know if they bother you or last more than a few days. Let your doctor know if you notice yellowing of skin or eyes, unusually dark urine or dark stools, as these might be symptoms of liver damage. You may be asked for regular monitoring of your blood sugar level and liver function while taking this medicine.


Before taking this medicine, let your doctor know if you have any kidney or liver problems or high blood pressure. Pregnant women should also consult their doctor before taking it. You should also inform your doctor about all other medications you are taking, as they may interact with or be affected by this medicine.

Uses of Cresadex Tablet

Benefits of Cresadex Tablet

Treatment of High cholesterol
High cholesterol is a condition where excess cholesterol builds up in the blood, increasing the risk of heart disease and stroke. Cresadex 20 Plus Tablet helps lower bad cholesterol (LDL) and triglycerides while increasing good cholesterol (HDL), supporting better heart and blood vessel health.

Side effects of Cresadex Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Cresadex
  • Flu
  • Back pain
  • Pain in extremity
  • Fatigue
  • Nausea
  • Constipation
  • Headache
  • Weakness
  • Diarrhea
  • Joint pain
  • Runny nose
  • Sore throat
  • Common cold

How to use Cresadex Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Cresadex 20 Plus Tablet may be taken with or without food.

How Cresadex Tablet works

Cresadex 20 Plus Tablet is a combination of two medicines: rosuvastatin and ezetimibe. Rosuvastatin reduces cholesterol production in the liver by inhibiting the HMG-CoA reductase enzyme, leading to lower "bad" LDL cholesterol levels. Ezetimibe complements this by blocking the absorption of cholesterol in the intestines. Together, these actions effectively reduce cholesterol levels and help manage the risk of cardiovascular diseases.

Quick tips

  • Take it in addition to regular exercise and a low-fat diet to lower levels of fat in the blood.
  • Notify your doctor if you experience stomach pain, loss of hunger, a sick feeling, dark urine, or muscle symptoms (pain or weakness), particularly if accompanied by fever.
  • Cresadex 20 Plus Tablet can be taken with or without food. But take it regularly and at the same time each day for the best results.

Safety advice

Alcohol

Alcohol

CAUTION
Alcohol should be used with caution while taking Cresadex 20 Plus Tablet.
Pregnancy

Pregnancy

UNSAFE
Cresadex 20 Plus Tablet is highly unsafe during pregnancy. It can cause serious harm to the unborn baby, including birth defects and pregnancy loss. Do not use this medicine if you are pregnant or planning to become pregnant.
Breast feeding

Breast feeding

UNSAFE
Cresadex 20 Plus Tablet is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.
Driving

Driving

CONSULT YOUR DOCTOR
It is not known whether Cresadex 20 Plus Tablet alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react. Please consult your doctor.
Kidney

Kidney

CAUTION
Cresadex 20 Plus Tablet should be used with caution in patients with kidney disease. Dose adjustment may be needed.
Use of Cresadex 20 Plus Tablet is not recommended in patients with severe kidney disease.
Liver

Liver

UNSAFE
Cresadex 20 Plus Tablet is unsafe to use in patients with liver disease and should be avoided.
Use of Cresadex 20 Plus Tablet is not recommended in patients with moderate to severe liver disease.

Frequently asked questions

Cresadex 20 Plus Tablet is used to lower high cholesterol levels. It works by reducing the amount of cholesterol made by the liver, and also blocking cholesterol absorption from food. This helps lower “bad cholesterol” (LDL) and reduces the risk of heart attack and stroke.
Yes, Cresadex 20 Plus Tablet is usually prescribed to people who are already well-controlled on separate rosuvastatin and ezetimibe tablets. Your doctor may switch you to this medicine for convenience and better cholesterol management.
Individuals should not take Cresadex 20 Plus Tablet if they have active liver disease, unexplained high liver enzymes, severe kidney problems, muscle disorders, or are taking ciclosporin. It is also not safe during pregnancy or breastfeeding.
No, Cresadex 20 Plus Tablet should be used very carefully in people with liver disease or those who drink a lot of alcohol, because it can increase the risk of liver damage. Your doctor will decide if it is safe for you, and may monitor your liver closely.
Yes, in rare cases, Cresadex 20 Plus Tablet can cause muscle pain, weakness, or breakdown (rhabdomyolysis), which can lead to kidney damage. The risk is higher with the higher dose, or if you have kidney problems, thyroid disease, or a history of muscle issues. Always report unexplained muscle pain or weakness to your doctor right away.
Yes, statins like rosuvastatin (present in Cresadex 20 Plus Tablet) may slightly increase blood sugar levels. If you are at risk of diabetes or already have diabetes, your doctor may monitor your blood sugar while you are on this medicine.
Seek medical help immediately if you notice serious side effects of Cresadex 20 Plus Tablet such as unexplained muscle pain, severe tiredness, yellowing of the skin or eyes (signs of liver problems), dark urine, skin rashes or blisters (possible severe allergic reaction), or swelling in your face or throat.
Cresadex 20 Plus Tablet is usually safe for older adults, but those over 70 years may be started on a lower dose to reduce the risk of muscle problems. The doctor will monitor closely for side effects in older patients.

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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Aarkios Health Pvt Ltd
Address: No. 3-A, Bhagwan Mansion, 7 Cinema Road Behind Metro Cinema, Mumbai - 400020, Maharashtra, India

Vendor Details

Country of origin: India
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