Coxter Kit 4 Tablet


Overview

Uses of Coxter Kit 4 Tablet

Coxter Kit 4 Tablet is used in the treatment of tuberculosis.

Coxter Kit 4 Tablet side effects

Common
  • Nausea
  • Vomiting
  • Rash
  • Fever
  • Dark colored urine
  • Sweating
  • Increased sputum production
  • Salivation
  • Teary eyes
  • Peripheral neuropathy (tingling and numbness of feet and hand)
  • Increased liver enzymes
  • Jaundice
  • Increased uric acid level in blood
  • Visual impairment

How to use Coxter Kit 4 Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Coxter Kit 4 Tablet is to be taken empty stomach.
Avoid Coxter Kit 4 Tablet with tyramine-rich food such as cheese, smoked fish, meats and some types of beer.

How Coxter Kit 4 Tablet works

Coxter Kit 4 Tablet is a combination of four medicines: Isoniazid, rifampicin, ethambutol and pyrazinamide which treat tuberculosis. Isoniazid works by preventing the TB bacteria from forming their own protective covering, while rifampicin inactivates a bacterial enzyme (RNA-polymerase) which is required by TB bacteria to make essential proteins and to reproduce. Together, they kill the bacteria and eradicate the infection. Ethambutol and pyrazinamide on the other hand, work by slowing the growth of these bacteria.

Coxter Kit 4 Tablet related warnings

Alcohol
CAUTION
Coxter Kit 4 Tablet may cause symptoms such as flushing, increased heartbeat, nausea, thirst, chest pain and low blood pressure with alcohol (Disulfiram reactions).
Pregnancy
WEIGH RISKS VS BENEFITS
Coxter Kit 4 Tablet may be unsafe to use during pregnancy.
Animal studies have shown adverse effects on the foetus, however, there are limited human studies. The benefits from use in pregnant women may be acceptable despite the risk. Please consult your doctor.
Lactation
Coxter Kit 4 Tablet is probably safe to use during lactation. Limited human data suggests that the drug does not represent a significant risk to the baby.
Driving
Do not drive unless you are feeling well.
Coxter Kit 4 Tablet occasionally causes sight problems and tingling or numbness in hand or feet. After taking this medicine you should not drive until you know how it affects you.
Kidney
CAUTION
Coxter Kit 4 Tablet should be used with caution in patients with kidney disease. Dose adjustment of Coxter Kit 4 Tablet may be needed. Please consult your doctor.
Kidney function tests are advisable before the start of this medicine.
Liver
CAUTION
Coxter Kit 4 Tablet should be used with caution in patients with liver disease. Dose adjustment of Coxter Kit 4 Tablet may be needed. Please consult your doctor.
Regular monitoring of liver function tests is advised before and after the start of the treatment.

Alternate Brands

For informational purposes only. Consult a doctor before taking any medicines.
No alternate brands found for this medicine

Expert Advice

  • You have been prescribed Coxter Kit 4 Tablet for the treatment of tuberculosis.
  • Take it on an empty stomach and preferably at the same time everyday.
  • Try not to forget a dose, as this increases the risk of the bacteria becoming resistant to the medicine, and also increases the risk of getting side effects.
  • It may discolour your urine, sweat, saliva and tears a reddish/orange colour. This is normal and not harmful.
  • Your doctor may check your liver function before starting treatment and regularly thereafter. Inform your doctor if you notice yellowing of eyes or skin, dark urine, or stomach pain.
  • Avoid drinking alcohol while taking Coxter Kit 4 Tablet as this may increase the risk of side effects on the liver.
  • It may cause vitamin B6 deficiency. Your doctor may prescribe vitamin B6 supplements to help avoid potential problems associated with its deficiency, such as inflammation of the nerves (neuritis). 
  • Use a reliable contraceptive method (such as condoms or a diaphragm) to prevent pregnancy while you are taking Coxter Kit 4 Tablet as it may make hormonal contraceptives such as the pill less effective.
  • Do not take indigestion remedies (antacids)  within at least two hours of taking Coxter Kit 4 Tablet.
  • Finish the full course of the medication, even if you feel better. Stopping the course early increases the risk of coming back of the infection.

FAQs

Q. Can the use of Coxter Kit 4 cause discoloration of the urine?

Yes, Coxter Kit 4 contains Rifampicin. It can cause temporary discoloration of your teeth, sweat, urine, saliva and tears (red, orange or brown color). This side effect is usually not harmful. However, discoloration of urine can be a sign of liver damage. Contact your doctor if you notice discoloration of urine accompanied with stomach pain, loss of appetite and jaundice (yellowing of your skin or eyes).

Q. Can Coxter Kit 4 cause visual impairment?

Coxter Kit 4 contains Ethambutol which may cause visual impairment. Inform the doctor immediately if you notice any changes in your eyesight.

Q. Can I discontinue Coxter Kit 4 if I feel well?

No, do not discontinue Coxter Kit 4. Take the proper course of a drug that has been prescribed for you even if you begin to feel better. If you stop taking Coxter Kit 4 then your infection may become worse, difficult to treat and it may result in drug-resistant TB (drugs you are taking may no longer work).

Q. Can I take oral contraceptive pills while taking Coxter Kit 4?

No, Coxter Kit 4 can make birth control pills less effective. So, ask your doctor about using a birth control method which does not affect your hormone levels (such as a condom, diaphragm, spermicide).

Q. What are the instructions for storage and disposal of Coxter Kit 4?

Keep this medicine in the container it came in, tightly closed. Store it according to the instructions mentioned on the pack or label. Dispose of the unused medicine. Make sure it is not consumed by pets, children and other people.

Q. How to take Coxter Kit 4?

Take Coxter Kit 4 on an empty stomach which means at least one hour before and two hours after a meal and with full glass of water.

Q. Can I drink alcohol while taking Coxter Kit 4?

No, avoid drinking alcohol while taking Coxter Kit 4. Drinking alcohol will increase the risk of hepatitis caused by Coxter Kit 4 because of isoniazid.
Information last updated by Dr. Varun Gupta, MD Pharmacology on 8th Mar 2017.
The medicine details are for information purpose only. Consult a doctor before taking any medicine.
Manufacturer/Marketer Address
Alkem Laboratories Limited, Devashish Building, Alkem House, Senapati Bapat Road, Lower Parel, Mumbai - 400 013.
NOT FOR SALE
We do not facilitate sale of this product at present