Coxerin Capsule

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Introduction

Coxerin Capsule is an antibiotic medicine used to treat drug-resistant tuberculosis. It is generally used in combination with other medicines. This medicine is used when the bacteria have developed resistance to other antibiotics.

Coxerin Capsule may be taken with or without food. You should take it regularly at evenly spaced intervals as per the dose and schedule prescribed by your doctor. Taking it at the same time every day will help you to remember to take it. You should always complete a full course of this antibiotic as prescribed by your doctor. Do not stop taking it until you have finished, even when you feel better. If you stop taking it early, some bacteria may survive and the infection may come back.

The most common side effects of this medicine include memory loss, confusion, insomnia (difficulty sleeping), and dizziness. Inform your doctor if you experience skin rashes, tremors, fits, problems with speech or movement, depression, or other changes in mood, thoughts, or behavior.

Before using it, you should tell your doctor if you are allergic to any antibiotics or have any kidney or liver problems. Pregnant and breastfeeding mothers should not take this medicine. Your doctor may get regular blood and urine tests while undergoing treatment with this medicine.

Uses of Coxerin Capsule

Benefits of Coxerin Capsule

In Tuberculosis (TB)

Coxerin Capsule is used to treat tuberculosis, an infectious disease that mainly affects the lungs but can affect other parts of the body as well. It kills the infection causing bacteria and helps in treating the infection. Take it in the dose and duration advised by the doctor. Your symptoms may improve before the infection is completely cured. Do not stop taking it without consulting your doctor as doing so may cause the infection to return or worsen. Follow your doctor’s instructions carefully to get maximum benefit.

Side effects of Coxerin Capsule

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Coxerin

  • Memory loss
  • Confusion
  • Insomnia (difficulty in sleeping)
  • Retching
  • Difficulty in speaking
  • Dizziness
  • Headache
  • Convulsion
  • Anemia (low number of red blood cells)
  • Stomach pain
  • Acne-like rash
  • Paresthesia (tingling or pricking sensation)
  • Numbness
  • Irritation
  • Vertigo
  • Inflammation of vein
  • Suicidal behaviors
  • Abnormal behavior
  • Sleepiness

How to use Coxerin Capsule

Take this medicine in the dose and duration as advised by your doctor. Coxerin Capsule may be taken with or without food, but it is better to take it at a fixed time.

How Coxerin Capsule works

Coxerin Capsule is an antibiotic. It kills bacteria by preventing them from forming their own protective covering (cell wall) which is required for their survival in the human body.

Safety advice

Alcohol
UNSAFE
Consuming alcohol while taking Coxerin Capsule may cause symptoms such as flushing, increased heart beat, nausea, thirst, chest pain and low blood pressure (Disulfiram reaction).
Pregnancy
CONSULT YOUR DOCTOR
Coxerin Capsule may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Breast feeding
SAFE IF PRESCRIBED
Coxerin Capsule is safe to use during breastfeeding. Human studies suggest that the drug does not pass into the breastmilk in a significant amount and is not harmful to the baby.
Driving
UNSAFE
Coxerin Capsule may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
Kidney
CAUTION
Coxerin Capsule should be used with caution in patients with kidney disease. Dose adjustment of Coxerin Capsule may be needed. Please consult your doctor.
Use of Coxerin Capsule is not recommended in patients with severe kidney disease.
Liver
CONSULT YOUR DOCTOR
There is limited information available on the use of Coxerin Capsule in patients with liver disease. Please consult your doctor.

What if you forget to take Coxerin Capsule?

If you miss a dose of Coxerin Capsule, consult your doctor.

All substitutes

For informational purposes only. Consult a doctor before taking any medicines.
Coxerin Capsule
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Quick tips

  • Coxerin Capsule is used in combination with other medicines for the treatment of tuberculosis.
  • Take it at the same time every day to help you remember to take it.
  • Coxerin Capsule may cause dizziness or sleepiness. Do not drive or do anything requiring concentration until you know how it affects you.
  • Avoid drinking alcohol while taking Coxerin Capsule as this may worsen the side effects.
  • During treatment, you will need to have regular blood tests to monitor your kidney and liver function, blood cell counts and the amount of medicine in your blood.
  • Stop taking Coxerin Capsule and inform your doctor if you experience skin rashes, headaches, tremor, fits, problems with speech or movement, depression, or other changes in mood, thoughts or behavior.
  • Do not stop taking this medicine until your doctor tells you to.

Fact Box

Chemical Class
Isoxazolines derivative
Habit Forming
No
Therapeutic Class
ANTI INFECTIVES
Action Class
Cell wall active agent

Interaction with drugs

Taking Coxerin with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
Brand(s): Efzu, Alfuzee, Alfuflo
SERIOUS

Patient concerns

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My daughter is given tb medicine even though she is not infected taking these medicine will cause tb???
Dr. Rahul Yadav
Paediatrics
Hello, TB medicines are given only when there is indication of tuberculosis. They are for treating tuberculosis.
Though took vaccines in childhood, the test for TB came positive. Was advised to undergo treatment.physically absolute fit and healthy, is it advisable to take treatment?
Dr. Anshum Aneja Arora
Pulmonology
If sputum is positive for Tb , treatment is absolutely essential. Read more at www.arohealth.com/tuberculosis
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Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover all possible side effects, drug interactions or warnings or alerts. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

References

  1. Gumbo T. Chemotherapy of Tuberculosis, Mycobacterium Avium Complex Disease, and Leprosy. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. pp. 1562-63.
  2. Chambers HF, Deck DH. Beta-Lactam and Other Cell Wall- & Membrane-Active Antibiotics. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. p. 789.
  3. Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 339-40.
  4. Cycloserine [package insert]. Daman, India: Macleods Pharmaceuticals Limited; 2007 [revised Feb. 2015]. (online) Available from: External Link
  5. DailyMed. Cycloserine. [Accessed 01 Apr. 2019] (online) Available from:External Link
  6. Drugs.com. Cycloserine. [Accessed 01 Apr. 2019] (online) Available from:External Link
  7. Chaves RG, Lamounier JA. Breastfeeding and maternal medications. J Pediatr (Rio J). 2004;80(5 Suppl):S189-98. [Accessed 01 Apr. 2019] (online) Available from:External Link

Manufacturer/Marketer address

Atlanta Arcade, Marol Church Road, Andheri (East), Mumbai - 400059, INDIA.
Country of origin: India

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