Corel Plus Tablet is a combination of two medicines. It is used in the treatment of depression associated with anxiety. It helps in regulating mood and to reduce anxiety.

Corel Plus Tablet is taken with or without food. However, it is advised to take it at a fixed time each day to maintain a consistent level of medicine in the blood. In case you miss a dose of this medicine, take it as soon as you remember. Never skip any dose and finish the full course of treatment even if you feel better. It is important that this medication is not stopped suddenly without talking to the doctor as it may worsen your symptoms. Taking this medicine for a long time may require regular monitoring of blood and liver functions.

Some common side effects of this medicine include constipation, difficulty in urination, weight gain, confusion, orthostatic hypotension (sudden lowering of blood pressure on standing). This medicine may cause weight loss. In case of losing weight, consult a dietitian for dietary supplements or try to increase your food portion. Most of the common side effects tend to be mild. Your doctor may be able to suggest ways of preventing or reducing side effects if they bother you or do not go away. Serious side effects are rare. Remember to inform your doctor if you develop any unusual changes in mood as it may lead to suicidal thoughts.

Take caution while taking medicine if you are suffering from liver disease. Your doctor should also know about all other medicines you are taking as many of these may make this medicine less effective or change the way it works. Inform your doctor if you are pregnant, planning pregnancy or breastfeeding.

Uses of Corel Plus Tablet

Treatment of Depression

Benefits of Corel Plus Tablet

In Treatment of Depression

Corel Plus Tablet works by affecting the balance of certain chemicals (such as serotonin) in the brain. It helps improve mood and feelings of wellbeing, relieve anxiety and tension, helps you sleep better, and increase your energy level. It is an effective antidepressant but may cause drowsiness. You need to take it regularly as it is prescribed for it to be most effective and should not stop taking it suddenly.

Side effects of Corel Plus Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Corel Plus

Constipation
Difficulty in urination
Weight gain
Confusion
Orthostatic hypotension (sudden lowering of blood pressure on standing)
Tiredness
Blurred vision
Dryness in mouth
Increased heart rate
Uncoordinated body movements
Depression
Memory impairment

How to use Corel Plus Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Corel Plus Tablet may be taken with or without food, but it is better to take it at a fixed time.

How Corel Plus Tablet works

Corel Plus Tablet is a combination of two medicines: Amitriptyline and Chlordiazepoxide, which treats depression. Amitriptyline is a tricyclic antidepressant which increases the levels of chemical messengers in the brain that help in regulating the mood and treat depression. Chlordiazepoxide is a benzodiazepine (BZD) which works by increasing the action of GABA, a chemical messenger which suppresses the abnormal and excessive activity of the nerve cells in the brain.

Safety advice

Alcohol

UNSAFE

It is unsafe to consume alcohol with Corel Plus Tablet.

Pregnancy

CONSULT YOUR DOCTOR

Corel Plus Tablet is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.

Breast feeding

CONSULT YOUR DOCTOR

Corel Plus Tablet is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.

Driving

UNSAFE

Corel Plus Tablet may cause side effects which could affect your ability to drive.
As Corel Plus Tablet may make you feel drowsy or affect your concentration and this may affect your ability to drive.

Kidney

SAFE IF PRESCRIBED

Corel Plus Tablet is probably safe to use in patients with kidney disease. Limited data available suggests that dose adjustment of Corel Plus Tablet may not be needed in these patients. Please consult your doctor.

Liver

CAUTION

Corel Plus Tablet should be used with caution in patients with liver disease. Dose adjustment of Corel Plus Tablet may be needed. Please consult your doctor.

What if you forget to take Corel Plus Tablet?

If you miss a dose of Corel Plus Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

All substitutes

For informational purposes only. Consult a doctor before taking any medicines.

Corel Plus Tablet

₹3.0/Tablet

Chlormit H Tablet

D D Pharmaceuticals

₹1.5/tablet

50% cheaper

Triptal Plus Tablet

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₹2.1/tablet

30% cheaper

Chlormit Tablet

D D Pharmaceuticals

₹2.2/tablet

27% cheaper

Ditryp Plus Tablet

Kloster Pharmaceuticals

₹2.31/tablet

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Tryp CH Tablet

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₹2.6/tablet

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View all substitutes

Quick tips

Corel Plus Tablet is prescribed for the treatment of depression.
It can take a week or two after starting this treatment before the effect begins to build up, and 4-6 weeks before you feel the full benefit. Do not stop taking it after a week or two, feeling it is not helping.
Do not stop taking Corel Plus Tablet unless your doctor tells you to do so. Stopping treatment suddenly can cause problems and your doctor will probably want you to reduce your dose gradually when this becomes necessary.
Try to keep your regular appointments with your doctor. This is so your doctor can check on your progress.
Inform your doctor if you are taking any other antidepressants.
Inform your doctor immediately if you get thoughts about harming yourself or ending your life.
Avoid alcohol while taking Corel Plus Tablet.
If you have diabetes, you will be asked to monitor your blood glucose level regularly as Corel Plus Tablet may affect the levels of sugar in your blood.
Corel Plus Tablet is prescribed for the treatment of depression.
It can take a week or two after starting this treatment before the effect begins to build up, and 4-6 weeks before you feel the full benefit. Do not stop taking it after a week or two, feeling it is not helping.
Do not stop taking Corel Plus Tablet unless your doctor tells you to do so. Stopping treatment suddenly can cause problems and your doctor will probably want you to reduce your dose gradually when this becomes necessary.
Try to keep your regular appointments with your doctor. This is so your doctor can check on your progress.
Inform your doctor if you are taking any other antidepressants.
Inform your doctor immediately if you get thoughts about harming yourself or ending your life.
Avoid alcohol while taking Corel Plus Tablet.
If you have diabetes, you will be asked to monitor your blood glucose level regularly as Corel Plus Tablet may affect the levels of sugar in your blood.

Fact Box

Habit Forming

Yes

Therapeutic Class

NEURO CNS

Patient concerns

DEPRESSION SUFFERING FROM DEPRESSION

Dr. Jyoti Kapoor Madan

Psychiatry

Depression is a persistent state of sadness that is the result of interaction between one's inner biological and psychological state and gets triggered of with environmental stressors. Reactive depression is in response to a situation like loss, sickness, trauma etc. Endogenous depression occurs without any noticeable environmental stressors. Psychological symptoms include lack of interest, negative thinking, irritability, frustration, feeling demotivated etc. Somatic symptoms like fatigue/ weakness/ lack of sleep/ lack of appetite and other physical symptoms are common. Anxiety is common. In severe cases one may feel helpless and hopeless enough to wish for death or attempt suicide. Treatment includes physical and psychiatric work up following which medicines can be prescribed. In milder cases, psychotherapy or counselling is recommended.

Depression,anexity,body. Laziness Depression anxiety,f ear,body laziness

Dr. Ankur Kumar Tanwar

Ayurveda

Ok since how many months you are suffer from

Depression, anexity less sleep Chasing depression since last almost 9 years. But first depression episode was in 1998 immediately after recovering from maleria

Dr. Kirti Tandel

Psychiatry

Hello Mr. PATIENT is one of the most leading cause of morbidity worldwide. It is more prevalent than what it is thought to be. So I appreciate your fight against depression and may you stay healthy physically and mentally as well. Visit your psychiatrist regularly and have a good compliance with your medicines as well. Take care.

Depression. Thought of suicide

Dr. Jyoti Kapoor Madan

Psychiatry

Depression about current situation

Dr. Jyoti Kapoor Madan

Psychiatry

Depression is a persistent state of sadness that is the result of interaction between one's inner biological and psychological state and gets triggered of with environmental stressors. Endogenous depression occurs without any noticeable environmental stressors. Psychological symptoms include lack of interest, negative thinking, irritability, frustration, feeling demotivated etc. Somatic symptoms like fatigue/ weakness/ lack of sleep/ lack of appetite and other physical symptoms are common. Anxiety is common. In severe cases one may feel helpless and hopeless enough to wish for death or attempt suicide. Treatment includes physical and psychiatric work up following which medicines can be prescribed. In milder cases, psychotherapy or counselling is recommended.

FAQs

Q. Are there any important warnings associated with use of Corel Plus Tablet?

During the first few months of treatment, Corel Plus Tablet may increase suicidal thoughts or actions in some patients. Patients having mood or behavioral disorder have a high risk of developing suicidal thoughts and actions. You should pay close attention and report your doctor of any such behavior or mood changes. Make sure that you visit the doctor for the scheduled follow-up appointments.

Q. Can I stop taking Corel Plus Tablet when my symptoms are relieved?

No, you should continue to take Corel Plus Tablet, even if you feel well. If you stop Corel Plus Tablet suddenly, serious withdrawal symptoms may occur. Consult your doctor if the symptoms are relieved, he might decrease your dose gradually.

Q. How to manage weight gain associated with the use of Corel Plus Tablet?

There are reports which suggest that the use of Corel Plus Tablet can cause weight gain. If you maintain good eating habits and exercise regularly, you might not gain any weight. An important to remember is that it is easier to prevent weight gain than losing increased weight.

Q. What are the instructions for storage and disposal of Corel Plus Tablet?

Keep this medicine in the container or the pack it came in, tightly closed. Store it according to the instructions mentioned on the pack or label. Dispose of the unused medicine. Make sure it is not consumed by pets, children and other people.

Q. Can the use of Corel Plus Tablet cause sleepiness?

Yes, Corel Plus Tablet can make you feel sleepy. Avoid driving, operating machinery, working at heights or participating in potentially dangerous activities till you know how this medicine affects you.

Q. Can the use of Corel Plus Tablet affect my sexual life?

The use of Corel Plus Tablet can affect the sexual life of both men and women. Most commonly caused problems are decreased sexual desire, erectile dysfunction (inability to develop or maintain erection during the sexual activity) and inability to reach orgasm. It can also cause a decrease in satisfaction and cause discomfort while having sex. If you experience these problems, discuss with your doctor.

Q. Can I drink alcohol while taking Corel Plus Tablet?

No, do not drink alcohol while you are taking Corel Plus Tablet. Drinking alcohol can increase the severity of drowsiness or sleepiness caused by Corel Plus Tablet.

Q. Can the use of Corel Plus Tablet change the color of urine?

Yes, Corel Plus Tablet can the change the color of the urine to blue or green. This change of color is expected while using Corel Plus Tablet, and it is not harmful. Your urine color becomes normal once you stop taking Corel Plus Tablet.

Q. How long does Corel Plus Tablet take to work?

Everybody responds differently to the treatment. In general, it can take several weeks to feel the full benefits of Corel Plus Tablet, although some people will start to feel better sooner. When taking Corel Plus Tablet, it is important to give it time to work.

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Disclaimer:

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

References

DailyMed. Chlordiazepoxide and amitriptyline hydrochloride. [Accessed 10 Apr. 2019] (online) Available from:
Amitriptyline. North Harrow, Middlesex: Accord Healthcare Limited; 2018. [Accessed 10 Apr. 2019] (online) Available from:
MedlinePlus. Chlordiazepoxide. [Accessed 10 Apr. 2019] (online) Available from:

Manufacturer/Marketer address

Thrift Pharmaceuticals Private Limited, Kh--136, raipur Industrial Area Behind Pritam International, Roorkee-247661, Uttarakhand, India

Country of origin: India

NOT FOR SALE

We do not facilitate sale of this product at present