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MD (Pharmacology), MBBS
Last updated:
16 Oct 2019 | 01:31 PM (IST)
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Corel Forte Tablet



Corel Forte Tablet is a combination of two medicines. It is used in the treatment of depression associated with anxiety. It helps in regulating mood and to reduce anxiety.

Corel Forte Tablet is taken with or without food. However, it is advisable to take it at a fixed time each day to maintain consistent level of medicine in the blood. In case you miss a dose of this medicine, take it as soon as you remember. Never skip any dose and finish the full course of treatment even if you feel better. It is important that this medication is not stopped suddenly without talking to the doctor as it may worsen your symptoms. Taking this medicine for long time may require regular monitoring of blood and liver functions.

Some common side effects of this medicine include insomnia, agitation, anxiety and a feeling of worthlessness. This medicine may cause weight loss. So, in case you lose weight, consult a dietitian for dietary supplement or try to increase your food portion. Remember to inform your doctor if you develop any unusual changes in mood as it may lead to suicidal thoughts.

Uses of Corel Forte Tablet

Side effects of Corel Forte Tablet

  • Constipation
  • Difficulty in urination
  • Weight gain
  • Confusion
  • Orthostatic hypotension (sudden lowering of blood pressure on standing)
  • Tiredness
  • Blurred vision
  • Dryness in mouth
  • Increased heart rate
  • Uncoordinated body movement
  • Depression
  • Memory impairement

How to use Corel Forte Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Corel Forte Tablet may be taken with or without food, but it is better to take it at a fixed time.

How Corel Forte Tablet works

Corel Forte Tablet is a combination of two medicines: Amitriptyline and Chlordiazepoxide, which treats depression. Amitriptyline is a tricyclic antidepressant which increases the levels of chemical messengers in the brain that help in regulating the mood and treat depression. Chlordiazepoxide is a benzodiazepine (BZD) which works by increasing the action of GABA, a chemical messenger which suppresses the abnormal and excessive activity of the nerve cells in the brain.

Safety Advice

It is unsafe to consume alcohol with Corel Forte Tablet.
Corel Forte Tablet is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.
Corel Forte Tablet is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
Corel Forte Tablet may cause side effects which could affect your ability to drive.
As Corel Forte Tablet may make you feel drowsy or affect your concentration and this may affect your ability to drive.
Corel Forte Tablet is probably safe to use in patients with kidney disease. Limited data available suggests that dose adjustment of Corel Forte Tablet may not be needed in these patients. Please consult your doctor.
Corel Forte Tablet should be used with caution in patients with liver disease. Dose adjustment of Corel Forte Tablet may be needed. Please consult your doctor.

Alternate Brands

For informational purposes only. Consult a doctor before taking any medicines.
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Patient Concerns

I started with nexito forte , one tablet/day after consulting psychiatrist again,he prescribed me nexito LS (bd) I am taking now nexito LS from last 45 days with almost 40% releif but negative thought still harms me What to do please help
Dr. Jyoti Kapoor Madan
Based on your clinical history, your doctor plans the type of medicine and it's dose and duration. For first episode of anxiety/ depression/ panic, the usual maintenance phase is 6 months of asymptomatic period, after which medicines can be gradually tapered. But treatment may need to continue longer depending on severity and frequency of episodes. To take any decision to change medication or stop them, several factors have to be taken in account for which regular follow up with your psychiatrist is important. For second opinion, seek a proper consultation with another psychiatrist and take along your previous prescriptions.
Dear sir I am a 32 yr old guy last few months i am feeling very sad i am loosing interest in everything i runs a pharmacy and i earn a good amount every month there is no tension in my life i am happily married but last few mmths i am fearing about something which i cant define my heart is beating faster and i am always afraid from my inner could not sleep in time could not concentrate always have a fear of unknown in my heart plz help me outSometimes i have a sleep disturbance i consulted a psychiatrist 10yrs ago he prescribed me nexito forte i had this tablet for a few days then i was ok i never visited the doctor after that actually i realised that i feel sleepy but could not sleep sometimes and whenever this problem arise i take nexito forte for a day or two then i keep it away this continues till date but last 1 month i am fearing in my heart it beats fast and i am afraid how can i get rid of it
Dr. Ambrish Dharmadhikari
Mental Wellness
From your detailed description, I can understand you are suffering from depression. Taking antidepressant (Nexito) off n on is not useful. Antidepressant takes time to act on. So please take medication regularly. And then discuss with doctor when to start reducing medication.
Do you have any questions related to Corel Forte Tablet ?


Q. What are the instructions for storage and disposal of Corel Forte?

Keep this medicine in the container or the pack it came in, tightly closed. Store it according to the instructions mentioned on the pack or label. Dispose of the unused medicine. Make sure it is not consumed by pets, children and other people.

Q. Are there any important warnings associated with use of Corel Forte?

During the first few months of treatment, Corel Forte may increase suicidal thoughts or actions in some patients. Patients having mood or behavioral disorder have a high risk of developing suicidal thoughts and actions. You should pay close attention and report your doctor of any such behavior or mood changes. Make sure that you visit the doctor for the scheduled follow-up appointments.

Q. Can I stop taking Corel Forte when my symptoms are relieved?

No, you should continue to take Corel Forte, even if you feel well. If you stop Corel Forte suddenly, serious withdrawal symptoms may occur. Consult your doctor if the symptoms are relieved, he might decrease your dose gradually.

Q. How to manage weight gain associated with the use of Corel Forte?

There are reports which suggest that the use of Corel Forte can cause weight gain. If you maintain good eating habits and exercise regularly, you might not gain any weight. An important to remember is that it is easier to prevent weight gain than losing increased weight.

Q. Can the use of Corel Forte cause sleepiness?

Yes, Corel Forte can make you feel sleepy. Avoid driving, operating machinery, working at heights or participating in potentially dangerous activities till you know how this medicine affects you.

Q. Can the use of Corel Forte affect my sexual life?

The use of Corel Forte can affect the sexual life of both men and women. Most commonly caused problems are decreased sexual desire, erectile dysfunction (inability to develop or maintain erection during the sexual activity) and inability to reach orgasm. It can also cause a decrease in satisfaction and cause discomfort while having sex. If you experience these problems, discuss with your doctor.

Q. Can I drink alcohol while taking Corel Forte?

No, do not drink alcohol while you are taking Corel Forte. Drinking alcohol can increase the severity of drowsiness or sleepiness caused by Corel Forte.

Q. Can the use of Corel Forte change the color of urine?

Yes, Corel Forte can the change the color of the urine to blue or green. This change of color is expected while using Corel Forte, and it is not harmful. Your urine color becomes normal once you stop taking Corel Forte.

Q. How long does Corel Forte take to work?

Everybody responds differently to the treatment. In general, it can take several weeks to feel the full benefits of Corel Forte, although some people will start to feel better sooner. When taking Corel Forte, it is important to give it time to work.

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Disclaimer: 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover all possible side effects, drug interactions or warnings or alerts. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.
  1. DailyMed. Chlordiazepoxide and amitriptyline hydrochloride. [Accessed 10 Apr. 2019] (online) Available from:External Link
  2. Amitriptyline. North Harrow, Middlesex: Accord Healthcare Limited; 2018. [Accessed 10 Apr. 2019] (online) Available from:External Link
  3. MedlinePlus. Chlordiazepoxide. [Accessed 10 Apr. 2019] (online) Available from:External Link
Manufacturer/Marketer Address
Thrift Pharmaceuticals Private Limited, Kh--136, raipur Industrial Area Behind Pritam International, Roorkee-247661, Uttarakhand, India
We do not facilitate sale of this product at present


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