Combutol 800 mg Tablet

Prescription Required

Overview

Uses of Combutol Tablet
Combutol 800 mg Tablet is used in the treatment of tuberculosis.
Combutol Tablet side effects
Common
  • Visual impairment
  • Color blindness
How to use Combutol Tablet
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Combutol 800 mg Tablet is to be taken with food.
How Combutol Tablet works
Combutol 800 mg Tablet is an antibiotic. It works by slowing the growth of bacteria that causes tuberculosis.
Combutol Tablet related warnings
Alcohol
Interaction with alcohol is unknown. Please consult your doctor.
Pregnancy
WEIGH RISKS VS BENEFITS
Combutol 800 mg Tablet may be unsafe to use during pregnancy.
Animal studies have shown adverse effects on the foetus, however, there are limited human studies. The benefits from use in pregnant women may be acceptable despite the risk. Please consult your doctor.
Lactation
SAFE
Combutol 800 mg Tablet is safe to use during lactation. Human studies have shown that either the drug does not pass into the breastmilk in significant amount or is not expected to cause toxicity to the baby.
Driving
Do not drive unless you are feeling well.
Combutol 800 mg Tablet occasionally causes sight problems and tingling or numbness in hand or feet. After taking this medicine you should not drive until you know how it affects you.
Kidney
CAUTION
Combutol 800 mg Tablet should be used with caution in patients with kidney disease. Dose adjustment of Combutol 800 mg Tablet may be needed. Please consult your doctor.
Kidney function tests are advisable before the start of this medicine.
Liver
CAUTION
Combutol 800 mg Tablet should be used with caution in patients with liver disease. Dose adjustment of Combutol 800 mg Tablet may be needed. Please consult your doctor.
What if you miss a dose of Combutol Tablet?
If you miss a dose of Combutol 800 mg Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

Alternate Brands

For informational purposes only. Consult a doctor before taking any medicines.
Combutol 800 mg Tablet
₹4.17/Tablet
Mycobutol 800mg Tablet
Cadila Pharmaceuticals Ltd
₹4.17/Tablet
same price
Ecox 800mg Tablet
Macleods Pharmaceuticals Pvt Ltd
₹4.17/Tablet
same price
Themibutol 800mg Tablet
Themis Medicare Ltd
₹4.17/Tablet
same price
Tabutol 800mg Tablet
S.S.M Pharmaceuticals
₹5.3/Tablet
27% costlier
Concox 800mg Tablet
Concept Pharmaceuticals Ltd
₹4.85/Tablet
16% costlier

Expert Advice

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  • Your doctor has prescribed Combutol 800 mg Tablet to cure your infection and improve symptoms.
  • You can take it with food or on an empty stomach.
  • Tell your doctor immediately if you experience vision changes or eye pain, swelling of face, rashes, breathing difficulty, numbness, headache, fever or chills.

Interaction with Drugs

Taking Combutol with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
Brand(s): Sodamax, Sobinix, Sobimed
MINOR
Brand(s): Magflux, Magasip
MINOR

Patient Concerns

Questions Related to Combutol

Is it cure eye vision that is effect of drug COMBUTOL 800 mg. The vision is blur.
Dr. Vikas Sharma
Neurologist
stop combutol immediately; get eye checkup done; start tab neurobion forte 1 BD
Sgot 42.8, sgpt 47.10. Taking recin 300, combutol 800, cifrocin 5 mg
Dr. Sunil Sekhri
Diabetes Specialist
Since you are taking medication of tuberculosis increase in Liver enzymes does happen. If you develop jaundice then change of medications might be required
Do you have any questions related to Combutol 800 mg Tablet?

User Feedback


FAQs

Q. Does Combutol cause blindness?
Optic neuritis (inflammation of nerve fibers that transmit visual information from your eye to the brain) is one of the side effects of Combutol which causes several forms of eye defect. Although these conditions are reversible upon discontinuation of the drug, rare cases of irreversible blindness have also been reported. Please contact your doctor immediately if you notice any of these symptoms: decreased clearness of vision, loss of vision, disturbed vision due to blind spots, color blindness, visual field defect and eye pain
Q. Does Combutol induce hyperuricemia/how does Combutol induce hyperuricemia?
Yes. Increase in blood levels of uric acid is a side effect of Combutol. It increases the retention of uric acid in the body by decreasing the excretion of urates (uric acid) by the kidneys
Q. How does Combutol work in the body?
Combutol is an antibiotic effective against tuberculosis causing bacteria. It suppresses the growth of the bacteria by interfering with the formation of the outer protective covering (cell wall) of the bacteria, thereby weakening the bacteria
Q. What is Combutol toxicity/How does Combutol cause optic neuritis/how does Combutol affect vision?
Combutol toxicity involves toxic effects on the eyes (optic neuritis/optic neuropathy) which are related to the dose and duration of Combutol treatment. It causes optic neuritis (inflammation of nerve fibers in the eye) by interfering with important cellular activities (mitochondrial toxicity) in the nerve cells and inducing nerve damage (neuropathy) thereby affecting the transmission of visual information from the eye to brain. The symptoms of Combutol induced optic neuritis include: decreased clearness of vision, loss of vision, disturbed vision due to blind spots, color blindness, visual field defect and eye pain
Q. What does Combutol treat?
Combutol is an antibiotic effective against tuberculosis causing bacteria. It is used in the prevention, treatment and second time treatment of tuberculosis (a serious infection caused by bacteria that affects the lungs and in certain cases other parts of the body)
Q. Is Combutol bacteriostatic or bactericidal?
Combutol is both a bacteriostatic and a bactericidal antibiotic. It suppresses the growth of bacteria (bacteriostatic) by interfering with the formation of the outer protective covering (cell wall) of the bacteria, thereby weakening it and causing cell death in certain cases (bactericidal)
Q. Is Combutol hepatotoxic?
Liver toxicities are among the known side effects of Combutol. Inflammation of liver (hepatitis), abnormal liver function causing yellowing of skin and eyes (jaundice), abnormal liver function tests (blood tests to assess health of liver) and very rarely liver failure have been noted in patients receiving multi drug (including Combutol) treatment for tuberculosis. Please contact your doctor before taking Combutol if you have any liver problems
Q. Is Combutol toxicity reversible?
In most cases Combutol toxicities are related to dose (depends upon the quantity of Combutol you take) and duration of treatment and are reversible upon discontinuation. However, serious irreversible damage to eye and liver has been reported in rare cases
Q. Is Combutol chemotherapy?
Combutol is an antibiotic used in the treatment of tuberculosis. Do not confuse it with chemotherapy or chemo drugs used for the treatment of cancer
Q. Combutol is effective against?
Combutol is effective against most tuberculosis causing bacteria belonging to Mycobacterium family (M. tuberculosis, M. avium complex, M. kansasii, M. marinum).
Information last updated by Dr. Varun Gupta, MD Pharmacology on 6th Sep 2018.
Manufacturer/Marketer Address
Lupin Ltd, 3rd floor Kalpataru Inspire, Off. W E Highway, Santacruz (East), Mumbai 400 055. India
NOT FOR SALE
We do not facilitate sale of this product at present
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