Medicine Overview of Combutol Tablet
Combutol 800mg Tablet is used in the treatment of tuberculosis
Visual impairment, Color blindness.
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Combutol 800mg Tablet is to be taken with food.
Combutol 800mg Tablet is an antibiotic. It works by slowing the growth of bacteria that causes tuberculosis.
In Depth Information on Combutol Tablet
Do consult your doctor before taking ethambutol if you have any eye problems such as cataracts (disturbed vision due to clouding of eye lenses) , recurrent inflammatory conditions of the eye, optic neuritis (inflammation of nerve fibers that transmit visual information from your eye to the brain), and diabetic retinopathy (a complication of eye due to diabetes). Ethambutol can cause serious eye damage. Regular eye checkups are recommended while on treatment with ethambutol.
Do consult your doctor before taking ethambutol:
- If you have kidney problems.
- If you have liver problems.
- If you have gout (pain, swelling, redness and stiffness in joints due to accumulation of uric acid).
Ethambutol is not recommended for use in children aged below 3 years.
Do consult your doctor before taking ethambutol if you are pregnant or planning to become pregnant.
Do consult your doctor before taking ethambutol if you are breastfeeding.
Do not stop taking ethambutol without consulting your doctor. If you forget to take a dose of ethambutol, take it as soon as you remember. Do not double the dose to make up for the missed dose.
Combutol Tablet related warnings
Interaction with alcohol is unknown. Please consult your doctor.
WEIGH RISKS VS BENEFITS
Combutol 800mg Tablet may be unsafe to use during pregnancy.
Animal studies have shown adverse effects on the foetus, however, there are limited human studies. The benefits from use in pregnant women may be acceptable despite the risk. Please consult your doctor.
Combutol 800mg Tablet is safe to use during lactation.
Human studies have shown that either the drug does not pass into the breastmilk in significant amount or is not expected to cause toxicity to the baby.
Do not drive unless you are feeling well.
Combutol 800mg Tablet occasionally causes sight problems and tingling or numbness in hand or feet. After taking this medicine you should not drive until you know how it affects you.
Combutol 800mg Tablet should be used with caution in patients with kidney disease. Dose adjustment of Combutol 800mg Tablet may be needed. Please consult your doctor.
Kidney function tests are advisable before the start of this medicine.
Combutol 800mg Tablet should be used with caution in patients with liver disease. Dose adjustment of Combutol 800mg Tablet may be needed. Please consult your doctor.
If you miss a dose of Combutol 800mg Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
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Frequently asked questions about Combutol Tablet
Optic neuritis (inflammation of nerve fibers that transmit visual information from your eye to the brain) is one of the side effects of Combutol which causes several forms of eye defect. Although these conditions are reversible upon discontinuation of the drug, rare cases of irreversible blindness have also been reported. Please contact your doctor immediately if you notice any of these symptoms: decreased clearness of vision, loss of vision, disturbed vision due to blind spots, color blindness, visual field defect and eye pain
Yes. Increase in blood levels of uric acid is a side effect of Combutol. It increases the retention of uric acid in the body by decreasing the excretion of urates (uric acid) by the kidneys
Combutol is an antibiotic effective against tuberculosis causing bacteria. It suppresses the growth of the bacteria by interfering with the formation of the outer protective covering (cell wall) of the bacteria, thereby weakening the bacteria
Combutol toxicity involves toxic effects on the eyes (optic neuritis/optic neuropathy) which are related to the dose and duration of Combutol treatment. It causes optic neuritis (inflammation of nerve fibers in the eye) by interfering with important cellular activities (mitochondrial toxicity) in the nerve cells and inducing nerve damage (neuropathy) thereby affecting the transmission of visual information from the eye to brain. The symptoms of Combutol induced optic neuritis include: decreased clearness of vision, loss of vision, disturbed vision due to blind spots, color blindness, visual field defect and eye pain
Combutol is an antibiotic effective against tuberculosis causing bacteria. It is used in the prevention, treatment and second time treatment of tuberculosis (a serious infection caused by bacteria that affects the lungs and in certain cases other parts of the body)
Combutol is both a bacteriostatic and a bactericidal antibiotic. It suppresses the growth of bacteria (bacteriostatic) by interfering with the formation of the outer protective covering (cell wall) of the bacteria, thereby weakening it and causing cell death in certain cases (bactericidal)
Liver toxicities are among the known side effects of Combutol. Inflammation of liver (hepatitis), abnormal liver function causing yellowing of skin and eyes (jaundice), abnormal liver function tests (blood tests to assess health of liver) and very rarely liver failure have been noted in patients receiving multi drug (including Combutol) treatment for tuberculosis. Please contact your doctor before taking Combutol if you have any liver problems
In most cases Combutol toxicities are related to dose (depends upon the quantity of Combutol you take) and duration of treatment and are reversible upon discontinuation. However, serious irreversible damage to eye and liver has been reported in rare cases
Combutol is an antibiotic used in the treatment of tuberculosis. Do not confuse it with chemotherapy or chemo drugs used for the treatment of cancer
Combutol is effective against most tuberculosis causing bacteria belonging to Mycobacterium family (M. tuberculosis, M. avium complex, M. kansasii, M. marinum).
Severely interacts with other drugs like
Taking Combutol with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
Medicines with composition Sodium Bicarbonate: Diosis, Sodanet, Nodosis, Auxisoda, Audosis, Sodapill, Nocidos, Sobinate, Sodarise, Sarpix, Sodac
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