Combutol 600 Tablet

Prescription Required
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Overview

Uses of Combutol Tablet

Combutol 600 Tablet is used in the treatment of tuberculosis.

Combutol Tablet side effects

Common
  • Visual impairment
  • Color blindness

How to use Combutol Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Combutol 600 Tablet is to be taken with food.

How Combutol Tablet works

Combutol 600 Tablet is an antibiotic. It works by slowing the growth of bacteria that causes tuberculosis.

Combutol Tablet related warnings

Alcohol
Interaction with alcohol is unknown. Please consult your doctor.
Pregnancy
WEIGH RISKS VS BENEFITS
Combutol 600 Tablet may be unsafe to use during pregnancy.
Animal studies have shown adverse effects on the foetus, however, there are limited human studies. The benefits from use in pregnant women may be acceptable despite the risk. Please consult your doctor.
Lactation
SAFE
Combutol 600 Tablet is safe to use during lactation. Human studies have shown that either the drug does not pass into the breastmilk in significant amount or is not expected to cause toxicity to the baby.
Driving
Do not drive unless you are feeling well.
Combutol 600 Tablet occasionally causes sight problems and tingling or numbness in hand or feet. After taking this medicine you should not drive until you know how it affects you.
Kidney
CAUTION
Combutol 600 Tablet should be used with caution in patients with kidney disease. Dose adjustment of Combutol 600 Tablet may be needed. Please consult your doctor.
Kidney function tests are advisable before the start of this medicine.
Liver
CAUTION
Combutol 600 Tablet should be used with caution in patients with liver disease. Dose adjustment of Combutol 600 Tablet may be needed. Please consult your doctor.

What if you miss a dose of Combutol Tablet?

If you miss a dose of Combutol 600 Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

Alternate Brands

For informational purposes only. Consult a doctor before taking any medicines.
Combutol 600 Tablet
₹3.48/Tablet
Mycobutol 600 Tablet
Cadila Pharmaceuticals Ltd
₹3.49/Tablet
same price
Ecox 600mg Tablet
Macleods Pharmaceuticals Pvt Ltd
₹3.09/Tablet
save 11%
Themibutol 600mg Tablet
Themis Medicare Ltd
₹3.37/Tablet
save 3%
Sunibutol 600mg Tablet
Sunij Pharma Pvt Ltd
₹4.29/Tablet
23% costlier
Koxylar 600mg Tablet
Lark Laboratories Ltd
₹2.22/Tablet
save 36%

Expert Advice

  • Combutol 600 Tablet is effective at treating tuberculosis when taken together with other antibacterial drugs.
  • It has to be taken for several months in order for it work properly (usually 6 months).
  • Take it with food to avoid stomach upset.
  • It can lower your blood sugar. If you have diabetes, monitor your blood sugar regularly.
  • Your doctor may monitor your liver function, vision and thyroid function while on treatment with this medicine.
  • Avoid consuming alcohol while taking this medication.
  • Do not stop taking Combutol 600 Tablet even if you start to feel better. Stopping early can  can result in treatment failure and in the development of drug-resistant tuberculosis. This can be life-threatening and lead to other serious health risks.

Interaction with Drugs

Taking Combutol with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
Brand(s): Magflux, Magasip
MINOR
Brand(s): Sodamax, Sobinix, Sobimed
MINOR

Patient Concerns

Questions Related to Combutol

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Is it cure eye vision that is effect of drug COMBUTOL 800 mg. The vision is blur.
Dr. Vikas Sharma
Neurologist
stop combutol immediately; get eye checkup done; start tab neurobion forte 1 BD
Sgot 42.8, sgpt 47.10. Taking recin 300, combutol 800, cifrocin 5 mg
Dr. Sunil Sekhri
Diabetes Specialist
Since you are taking medication of tuberculosis increase in Liver enzymes does happen. If you develop jaundice then change of medications might be required
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Do you have any questions related to Combutol 600 Tablet?

User Feedback


FAQs

Q. Does Combutol cause blindness?

Optic neuritis (inflammation of nerve fibers that transmit visual information from your eye to the brain) is one of the side effects of Combutol which causes several forms of eye defect. Although these conditions are reversible upon discontinuation of the drug, rare cases of irreversible blindness have also been reported. Please contact your doctor immediately if you notice any of these symptoms: decreased clearness of vision, loss of vision, disturbed vision due to blind spots, color blindness, visual field defect and eye pain

Q. Does Combutol induce hyperuricemia/how does Combutol induce hyperuricemia?

Yes. Increase in blood levels of uric acid is a side effect of Combutol. It increases the retention of uric acid in the body by decreasing the excretion of urates (uric acid) by the kidneys

Q. How does Combutol work in the body?

Combutol is an antibiotic effective against tuberculosis causing bacteria. It suppresses the growth of the bacteria by interfering with the formation of the outer protective covering (cell wall) of the bacteria, thereby weakening the bacteria

Q. What is Combutol toxicity/How does Combutol cause optic neuritis/how does Combutol affect vision?

Combutol toxicity involves toxic effects on the eyes (optic neuritis/optic neuropathy) which are related to the dose and duration of Combutol treatment. It causes optic neuritis (inflammation of nerve fibers in the eye) by interfering with important cellular activities (mitochondrial toxicity) in the nerve cells and inducing nerve damage (neuropathy) thereby affecting the transmission of visual information from the eye to brain. The symptoms of Combutol induced optic neuritis include: decreased clearness of vision, loss of vision, disturbed vision due to blind spots, color blindness, visual field defect and eye pain

Q. What does Combutol treat?

Combutol is an antibiotic effective against tuberculosis causing bacteria. It is used in the prevention, treatment and second time treatment of tuberculosis (a serious infection caused by bacteria that affects the lungs and in certain cases other parts of the body)

Q. Is Combutol bacteriostatic or bactericidal?

Combutol is both a bacteriostatic and a bactericidal antibiotic. It suppresses the growth of bacteria (bacteriostatic) by interfering with the formation of the outer protective covering (cell wall) of the bacteria, thereby weakening it and causing cell death in certain cases (bactericidal)

Q. Is Combutol hepatotoxic?

Liver toxicities are among the known side effects of Combutol. Inflammation of liver (hepatitis), abnormal liver function causing yellowing of skin and eyes (jaundice), abnormal liver function tests (blood tests to assess health of liver) and very rarely liver failure have been noted in patients receiving multi drug (including Combutol) treatment for tuberculosis. Please contact your doctor before taking Combutol if you have any liver problems

Q. Is Combutol toxicity reversible?

In most cases Combutol toxicities are related to dose (depends upon the quantity of Combutol you take) and duration of treatment and are reversible upon discontinuation. However, serious irreversible damage to eye and liver has been reported in rare cases

Q. Is Combutol chemotherapy?

Combutol is an antibiotic used in the treatment of tuberculosis. Do not confuse it with chemotherapy or chemo drugs used for the treatment of cancer

Q. Combutol is effective against?

Combutol is effective against most tuberculosis causing bacteria belonging to Mycobacterium family (M. tuberculosis, M. avium complex, M. kansasii, M. marinum).
The medicine details are for information purpose only. Consult a doctor before taking any medicine.
Manufacturer/Marketer Address
Lupin Ltd, 3rd floor Kalpataru Inspire, Off. W E Highway, Santacruz (East), Mumbai 400 055. India
NOT FOR SALE
We do not facilitate sale of this product at present