Combunex 300 mg/600 mg Tablet
Prescription RequiredProduct introduction
Combunex 300 mg/600 mg Tablet is a combination medicine used in the treatment of tuberculosis. It prevents the growth of the microorganisms that cause the infection.
Combunex 300 mg/600 mg Tablet is a prescription medicine and it is to be taken it as suggested by the doctor. It should be taken in an empty stomach and take it at a fixed time to ensure better efficacy. Do not consume more than the recommended dose, as this may have harmful effects on your body. If you miss a dose, take it as soon as you remember. The course of the treatment must be completed even if you feel better. Sudden discontinuation of the treatment may affect the potency of the medicine. The medicine may take some to show its effects on the symptoms. However, it is advised to consult the doctor if you feel an aggravation of the condition or if your condition does not improve.
Some common side effects of this medicine are nausea, vomiting, fever, dark-colored urine, sweating, increased saliva, etc. To cope up with the side effects, you should drink plenty of water. If any of the side effects get aggravated, you must consult your doctor immediately. Generally, serious side effects are rare. If you experience any allergic reaction (rashes, itching, swelling, shortness of breath, etc.), you must seek immediate medical help.
Before taking this medicine, you should tell your doctor if you are taking any medicines for any health condition. Patients with liver and kidney ailments must take this medicine with proper consultation and caution. Pregnant or breastfeeding women should also consult with the doctor before taking it. Avoid drinking alcohol as it can cause excessive drowsiness with this medicine. It usually does not impair your ability to drive, but you should not drive if it makes you feel sleepy or dizzy. During the treatment, you must take adequate rest and eat a healthy diet for a faster recovery. While on the medication, your doctor may ask for a few laboratory and diagnostic tests to know the effects of the medicine on your body.
Uses of Combunex Tablet
Benefits of Combunex Tablet
In Treatment of Tuberculosis (TB)
Tuberculosis is an infectious disease that mainly affects the lungs but can affect other parts of the body as well. Combunex 300 mg/600 mg Tablet helps treat tuberculosis by stopping the growth of bacteria causing infection. Your symptoms might improve after using Combunex 300 mg/600 mg Tablet. However, make sure to complete the full course of treatment. This will ensure that the infection is completely cured and prevent it from returning.
Side effects of Combunex Tablet
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Combunex
- Peripheral neuropathy (tingling and numbness of feet and hand)
- Increased liver enzymes
- Jaundice
- Increased uric acid level in blood
- Gout
- Visual impairment
How to use Combunex Tablet
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Combunex 300 mg/600 mg Tablet is to be taken on an empty stomach.
Avoid Combunex 300 mg/600 mg Tablet with tyramine-rich food such as cheese, smoked fish, meats and some types of beer.
Avoid Combunex 300 mg/600 mg Tablet with tyramine-rich food such as cheese, smoked fish, meats and some types of beer.
How Combunex Tablet works
Combunex 300 mg/600 mg Tablet is a combination of two medicines: isoniazid and ethambutol which treat tuberculosis. Isoniazid prevents the TB bacteria from forming their own protective covering. This kills the bacteria and eradicate the infection. Ethambutol, on the other hand works by slowing the growth of these bacteria.
Safety advice
Alcohol
UNSAFE
Consumption of alcohol with Combunex 300 mg/600 mg Tablet may cause a disulfiram-like reaction, leading to symptoms such as flushing, increased heart rate, low blood pressure, nausea, lightheadedness, and severe headache.
Pregnancy
CONSULT YOUR DOCTOR
The safety of Combunex 300 mg/600 mg Tablet during pregnancy has not been established. There are no adequate and well-controlled studies in pregnant women, and animal data on reproductive toxicity are insufficient. Your doctor will weigh the benefits and any potential risks before prescribing.
Breast feeding
SAFE IF PRESCRIBED
Available human data suggest that the drug does not pass into breast milk in clinically significant amounts and is unlikely to harm the infant.
Driving
UNSAFE
Combunex 300 mg/600 mg Tablet may cause side effects that could affect your ability to drive.
Combunex 300 mg/600 mg Tablet occasionally causes sight problems and tingling or numbness in hand or feet. After taking this medicine you should not drive until you know how it affects you.
Combunex 300 mg/600 mg Tablet occasionally causes sight problems and tingling or numbness in hand or feet. After taking this medicine you should not drive until you know how it affects you.
Kidney
CAUTION
Combunex 300 mg/600 mg Tablet should be used with caution in patients with kidney disease. Dose adjustment may be needed.
Kidney function tests are advisable before the start of this medicine.
Kidney function tests are advisable before the start of this medicine.
Liver
CAUTION
Combunex 300 mg/600 mg Tablet should be used with caution in patients with liver disease. Dose adjustment may be needed.
What if you forget to take Combunex Tablet?
If you miss a dose of Combunex 300 mg/600 mg Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
All substitutes
For informational purposes only. Consult a doctor before taking any medicines.
No substitutes found for this medicine
Quick tips
- Combunex 300 mg/600 mg Tablet should be taken on an empty stomach but at the same time every day.
- Do not skip any doses and finish the full course of treatment even if you feel better.
- It may cause dizziness. Don't drive or do anything that requires mental focus until you know how Combunex 300 mg/600 mg Tablet affects you.
- It is advisable to stay hydrated and drink plenty of water to overcome medicine side effects.
- Avoid consuming alcohol while taking this medication as it can enhance the dizziness.
- Your doctor may monitor your liver function, vision and thyroid function while on treatment with this medicine.
Fact Box
Habit Forming
No
Therapeutic Class
ANTI INFECTIVES
Patient concerns
User feedback
Patients taking Combunex 300 mg/600 mg Tablet
Once A Day
100%
What are you using Combunex Tablet for?
Tuberculosis *
100%
*Tuberculosis (TB)
FAQs
What is Combunex 300 mg/600 mg Tablet used for?
Combunex 300 mg/600 mg Tablet is used in the continuation phase of tuberculosis (TB) treatment. It helps stop the TB bacteria from multiplying and lowers the risk of drug resistance.
Does Combunex 300 mg/600 mg Tablet cure tuberculosis permanently?
Combunex 300 mg/600 mg Tablet is a part of a complete TB treatment plan, but is not used alone. When taken correctly with other TB medicines, they help cure tuberculosis and prevent relapse.
Who should not take Combunex 300 mg/600 mg Tablet?
Individuals should not take Combunex 300 mg/600 mg Tablet if they have severe liver disease, optic neuritis (serious eye nerve problems), previous severe reactions to isoniazid or ethambutol, or any other ingredient present in this medicine.
Can children take Combunex 300 mg/600 mg Tablet safely?
Combunex 300 mg/600 mg Tablet is not recommended for children under 13 years without careful monitoring. Also, since children may not report eye problems early, it is difficult to prevent eye damage in children. Separate doses are preferred in younger children.
What are the serious side effects of Combunex 300 mg/600 mg Tablet?
Serious side effects of Combunex 300 mg/600 mg Tablet include hepatitis (liver damage), vision problems like blurred vision or color blindness, severe allergic reactions, nerve problems (tingling or numbness), and rare blood disorders. If you experience any of these symptoms, seek immediate medical attention.
Why are regular eye checks important while taking Combunex 300 mg/600 mg Tablet?
Combunex 300 mg/600 mg Tablet may cause optic neuritis, leading to vision problems such as color blindness or reduced eyesight. Regular eye tests are important to detect early changes and prevent permanent damage.
Can Combunex 300 mg/600 mg Tablet damage the liver?
Yes, Combunex 300 mg/600 mg Tablet can cause severe liver damage, especially in people over 35, alcohol users, and those with existing liver disease. Monthly monitoring and liver function tests are strongly advised.
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Disclaimer:
Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.References
- Ethambutol. Ontario, Canada: Patheon Inc.; 2007. [Accessed 09 Apr. 2019] (online) Available from:
- Isoniazid. Nottingham, Nottinghamshire: Boots Contract Manufacturing; 2015. [Accessed 09 Apr. 2019] (online) Available from:
- Chaves RG, Lamounier JA. Breastfeeding and maternal medications. J Pediatr (Rio J). 2004;80(5 Suppl):S189-98. [Accessed 09 Apr. 2019] (online) Available from:
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Name: Lupin Ltd
Address: 3rd floor Kalpataru Inspire, Off. W E Highway, Santacruz (East), Mumbai 400 055. India
Country of origin: India
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