


Combitide Disk 50mcg/250mcg Tablet
Salmeterol (50mcg)+ Fluticasone Propionate (250mcg)
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Combitide Disk 50mcg/250mcg Tablet is used in the treatment of asthma (wheezing and shortness of breath) and chronic obstructive pulmonary disorder (a lung disorder in which the flow of air to the lungs is blocked). It relaxes the muscles of the air passages and making it easier to breathe.
Written By Dr. Lipika Khurana, PGDHHM, BDS,
Reviewed By Dr. Rajeev Sharma, MBA, MBBS,
Last updated on 20 Jan 2026 | 10:57 AM (IST)
Written By Dr. Lipika Khurana, PGDHHM, BDS,
Reviewed By Dr. Rajeev Sharma, MBA, MBBS,
Last updated on 20 Jan 2026 | 10:57 AM (IST)
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General Information
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Product introduction
Combitide Disk 50mcg/250mcg Tablet is taken in a dose and duration as advised by the doctor. The dose you are given will depend on your condition and how you respond to the medicine. You should keep taking this medicine for as long as your doctor recommends. If you stop treatment too early your symptoms may come back and your condition may worsen. Let your doctor know about all other medications you are taking as some may affect, or be affected by this medicine.
The most common side effects are nausea, vomiting, respiratory tract infection, fungal infections in the mouth, headache, dry mouth, hoarseness of voice, sore throat, cough, musculoskeletal (bone, muscle or joint) pain, and increased heart rate. If you get there, don’t stop taking it but do talk to your doctor. There are other, rarer side effects which can be serious. Talk to your doctor if you're worried about them. In general, you should be trying to avoid situations that make your asthma worse (your triggers) and try not to smoke.
Ask your doctor whether it’s safe to take this medicine if you're pregnant or breastfeeding. Before taking it, you should tell your doctor if you have any kidney or liver diseases so that your doctor can prescribe a suitable dose for you.
The most common side effects are nausea, vomiting, respiratory tract infection, fungal infections in the mouth, headache, dry mouth, hoarseness of voice, sore throat, cough, musculoskeletal (bone, muscle or joint) pain, and increased heart rate. If you get there, don’t stop taking it but do talk to your doctor. There are other, rarer side effects which can be serious. Talk to your doctor if you're worried about them. In general, you should be trying to avoid situations that make your asthma worse (your triggers) and try not to smoke.
Ask your doctor whether it’s safe to take this medicine if you're pregnant or breastfeeding. Before taking it, you should tell your doctor if you have any kidney or liver diseases so that your doctor can prescribe a suitable dose for you.
Uses of Combitide Disk Tablet
Benefits of Combitide Disk Tablet
Treatment of Chronic obstructive pulmonary disease (COPD)
Combitide Disk 50mcg/250mcg Tablet helps the airways in your lungs stay open. It relaxes the muscles of these airways. This makes it easier for air to get in and out. It will relieve symptoms such as tightness in your chest, shortness of breath, wheezing and coughing and help you carry out your daily activities more easily. This medicine is safe and effective. It usually starts to work within a few minutes and the effects can last up to several hours. Do not stop using it unless you are advised to by your doctor.
Combitide Disk 50mcg/250mcg Tablet helps the airways in your lungs stay open. It relaxes the muscles of these airways. This makes it easier for air to get in and out. It will relieve symptoms such as tightness in your chest, shortness of breath, wheezing and coughing and help you carry out your daily activities more easily. This medicine is safe and effective. It usually starts to work within a few minutes and the effects can last up to several hours. Do not stop using it unless you are advised to by your doctor.
Side effects of Combitide Disk Tablet
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Combitide Disk
- Dryness in mouth
- Headache
- Cough
- Upper respiratory tract infection
- Nasopharyngitis (inflammation of the throat and nasal passages)
- Sinus inflammation
- Stomach discomfort
- Fungal infection of oropharynx
- Tremors
- Palpitations
- Voice change
How to use Combitide Disk Tablet
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Combitide Disk 50mcg/250mcg Tablet may be taken with or without food.
How Combitide Disk Tablet works
Combitide Disk 50mcg/250mcg Tablet is a combination of two medicines: Salmeterol and Fluticasone Propionate. Salmeterol is a long-acting bronchodilator which works by relaxing the muscles in the airways and widens the airways. Fluticasone Propionate is a steroid. It works by stopping the release of certain chemical messengers that cause inflammation (swelling) of the airways. Together, they make breathing easier.
Quick tips
- This medicine is for inhalation only. The tablet should not be swallowed.
- It should be taken at the same time each day.
- It does not work right away and should not be used to relieve sudden breathing problems. Use your rescue inhaler to control sudden difficulty in breathing.
- Dry mouth may occur as a side effect. Frequent mouth rinses, good oral hygiene, increased water intake and sugarless candy may help.
- Gargle with warm water after each inhalation to avoid any fungal infections in your mouth and throat.
- Take the first dose of this medicine under medical supervision as it may cause wheezing or tightening of the airways (bronchospasm) immediately after using.
- Your doctor may regularly monitor your blood potassium level as low oxygen level in the blood (hypoxia) and medicines such as Combitide Disk 50mcg/250mcg Tablet can lower blood potassium level.
- Only miniscule amounts of Combitide Disk 50mcg/250mcg Tablet may get absorbed into the bloodstream after inhalation. Hence, serious side effects are unlikely.
Safety advice

Alcohol
UNSAFE
It is unsafe to consume alcohol with Combitide Disk 50mcg/250mcg Tablet

Pregnancy
CONSULT YOUR DOCTOR
The safety of Combitide Disk 50mcg/250mcg Tablet during pregnancy has not been established. There are no adequate and well-controlled studies in pregnant women, and animal data on reproductive toxicity are insufficient. Your doctor will weigh the benefits and any potential risks before prescribing.

Breast feeding
SAFE IF PRESCRIBED
Combitide Disk 50mcg/250mcg Tablet may be safe to use during breastfeeding. Animal studies have shown low or no adverse effects to the developing baby; however, there are limited human studies.

Driving
CONSULT YOUR DOCTOR
It is not known whether Combitide Disk 50mcg/250mcg Tablet alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react. Please consult your doctor.

Kidney
SAFE IF PRESCRIBED
Combitide Disk 50mcg/250mcg Tablet is probably safe to use in patients with kidney disease. Limited data suggest dose adjustment may not be needed.

Liver
CAUTION
Combitide Disk 50mcg/250mcg Tablet should be used with caution in patients with liver disease. Dose adjustment may be needed.
Frequently asked questions
No, do not stop taking Combitide Disk 50mcg/250mcg Tablet. If you stop taking Combitide Disk 50mcg/250mcg Tablet, your symptoms may come back and may lead to serious complications. Take your medicine as advised by your doctor.
No, taking more of this medicine will not make it more effective, rather it can lead to increased side effects. If symptoms are not getting relieved by the recommended doses, please consult the doctor for re-evaluation.
Keep this medicine in the container it came in, tightly closed. Store it according to the instructions mentioned on the pack or label. Dispose of the unused medicine. Make sure it is not consumed by pets, children and other people.
Combitide Disk 50mcg/250mcg Tablet is prescribed to treat Chronic Obstructive Pulmonary Disease and Asthma. The symptoms may include wheezing, shortness of breath, and breathing difficulties.
Fact Box
Habit Forming
No
Therapeutic Class
RESPIRATORY
References
- Fluticasone propionate and salmeterol inhalation aerosol. Research Triangle Park, North Carolina: GlaxoSmithKline; 2000 [Revised Feb. 2019]. [Accessed 18 Apr. 2019] (online) Available from:
- Fluticasone propionate/formoterol fumarate dihydrate. Cambridge, UK: Bard Pharmaceuticals Limited; 2018. [Accessed 24 Apr. 2019] (online) Available from:
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Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.
Marketer details
Name: Sun Pharma Laboratories Ltd
Address: Sun Pharmaceutical Industries Ltd., SUN HOUSE, CTS No. 201 B/1, Western Express Highway, Goregaon (E), Mumbai 400063
Address: Sun Pharmaceutical Industries Ltd., SUN HOUSE, CTS No. 201 B/1, Western Express Highway, Goregaon (E), Mumbai 400063
Vendor Details
Country of origin: India
Lab tests offered by us
- CBC (Complete Blood Count)
- FBS (Fasting Blood Sugar)
- Thyroid Profile Total (T3, T4 & TSH)
- HbA1c (Glycosylated Hemoglobin)
- PPBS (Postprandial Blood Sugar)
- Lipid Profile
- Vitamin D (25-Hydroxy)
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- Coronavirus Covid -19 test- RT PCR
- LFT (Liver Function Test)
- KFT (Kidney Function Test)
- TSH (Thyroid Stimulating Hormone) Ultrasensitive
- ESR (Erythrocyte Sedimentation Rate)
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