Clotihem 500mg/250mg Tablet
Prescription Required
View available alternative with same salt composition
Product introduction
Clotihem 500mg/250mg Tablet is a combination medicine used in the treatment of heavy menstrual bleeding. It works by preventing the breakdown of blood clots and controlling excessive bleeding. It also increases the ability of platelets to stick together and form blood clots.
You can take Clotihem 500mg/250mg Tablet at any time of day, with or without food, but it is best to take it at the same time each day. Keep taking it for as long as advised by your doctor. Take this medicine in the dose and duration advised by the doctor, and if you have missed a dose, take it as soon as you remember. Remember to finish the full course of treatment even if you feel better. This medication mustn't be stopped suddenly without talking to the doctor.
Common side effects of Clotihem 500mg/250mg Tablet include nausea, stomach pain, headache, nasal congestion, sinus pain, sinus inflammation, rash, tiredness, and musculoskeletal (bone, muscle, or joint) pain. It may also cause diarrhea, so it is better to drink plenty of fluids while taking this medicine, as it may help to prevent dehydration. It is advised to consult with your doctor if you do not notice any changes in periods after 3 consecutive periods.
Before taking it, let your doctor know if you have any kidney problems or vaginal bleeding disorder. Pregnant or breastfeeding women should also consult their doctor for advice before taking this medicine. You also need to tell your doctor what other medicines you are taking. You might be asked for eye check-ups while taking this medicine.
Uses of Clotihem Tablet
Benefits of Clotihem Tablet
In Heavy menstrual bleeding
Clotihem 500mg/250mg Tablet helps normal blood clotting, which reduces the bleeding during menstruation. It helps to prevent excessive loss of blood, stops bleeding and enhances the healing process. This helps prevent complications of excessive bleeding such as hemorrhage. If heavy periods become such a problem that they interfere with your everyday life, then try taking things a little easier on those days. Some women find that relaxation techniques or yoga help them feel more relaxed and reduce stress. Getting a lot of exercise can also help.
Side effects of Clotihem Tablet
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Clotihem
- Nausea
- Stomach pain
- Diarrhea
- Headache
- Nasal congestion (stuffy nose)
- Sinus pain
- Sinus inflammation
- Rash
- Tiredness
- Musculoskeletal (bone, muscle or joint) pain
- Anemia (low number of red blood cells)
- Dizziness
How to use Clotihem Tablet
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Clotihem 500mg/250mg Tablet may be taken with or without food, but it is better to take it at a fixed time.
How Clotihem Tablet works
Clotihem 500mg/250mg Tablet is a combination of two medicines: tranexamic acid and ethamsylate. Tranexamic acid is an antifibrinolytic. It works by preventing the breakdown of blood clots and controlling excessive bleeding. Ethamsylate is a hemostatic. It works by increasing the ability of platelets to stick together and form blood clots. It also helps control bleeding from tiny blood vessels (capillaries).
Safety advice
Alcohol
UNSAFE
Clotihem 500mg/250mg Tablet may cause excessive drowsiness with alcohol.
Pregnancy
CONSULT YOUR DOCTOR
Information regarding the use of Clotihem 500mg/250mg Tablet during pregnancy is not available. Please consult your doctor.
Breast feeding
CONSULT YOUR DOCTOR
Information regarding the use of Clotihem 500mg/250mg Tablet during breastfeeding is not available. Please consult your doctor.
Driving
CONSULT YOUR DOCTOR
It is not known whether Clotihem 500mg/250mg Tablet alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react.
Kidney
CAUTION
Clotihem 500mg/250mg Tablet should be used with caution in patients with kidney disease. Dose adjustment of Clotihem 500mg/250mg Tablet may be needed. Please consult your doctor.
Liver
SAFE IF PRESCRIBED
Clotihem 500mg/250mg Tablet is probably safe to use in patients with liver disease. Limited data available suggests that dose adjustment of Clotihem 500mg/250mg Tablet may not be needed in these patients. Please consult your doctor.
What if you forget to take Clotihem Tablet?
If you miss a dose of Clotihem 500mg/250mg Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
All substitutes
For informational purposes only. Consult a doctor before taking any medicines.
Clotihem 500mg/250mg Tablet
₹4.78/Tablet
Sylate T 500mg/250mg Tablet
Emcure Pharmaceuticals Ltd
₹46.4/tablet
871% costlier
Tranlok E 500mg/250mg Tablet
Aristo Pharmaceuticals Pvt Ltd
₹22.8/tablet
377% costlier
₹24.5/tablet
413% costlier
K-Stat-ET Tablet
Mercury Laboratories Ltd
₹25.8/tablet
440% costlier
Sylate T 500mg/250mg Tablet
Emcure Pharmaceuticals Ltd
₹30.17/tablet
531% costlier
Quick tips
- Stick to simple meals and avoid spicy food to avoid feeling sick (nausea).
- If you get diarrhea while taking this medicine, consult your doctor immediately.
- Along with taking Clotihem 500mg/250mg Tablet, you can use a heating pad or try gentle massage and relaxation techniques to get relief during periods.
- Inform your doctor if there is no improvement in your bleeding after using this medicine for three consecutive periods.
- Inform your doctor if you have any bleeding disorders.
Fact Box
Habit Forming
No
Therapeutic Class
BLOOD RELATED
Patient concerns
FAQs
Can the use of Clotihem 500mg/250mg Tablet cause diarrhea?
Yes, the use of Clotihem 500mg/250mg Tablet can cause diarrhea. In case of diarrhea, drink plenty of water or other fluids. Talk to your doctor if diarrhea persists. Do not take any other medicine without consulting a doctor.
Can I use oral contraceptives while using Clotihem 500mg/250mg Tablet?
No, do not use oral contraceptives while using Clotihem 500mg/250mg Tablet. Use of oral contraceptives along with this medicine increases the chance of serious complications.
Will a higher than the recommended dose of Clotihem 500mg/250mg Tablet be more effective?
No, taking a higher than recommended dose may not be more effective; rather, it may increase the chances of having serious side effects and toxicity. If the recommended doses do not relieve your symptoms, please consult your doctor.
What are the instructions for the storage and disposal of Clotihem 500mg/250mg Tablet?
Keep this medicine in the container it came in, tightly closed. Store it according to the instructions mentioned on the pack or label. Dispose of the unused medicine. Make sure it is not consumed by pets, children, or other people.
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Disclaimer:
Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.References
- Garay PR, Chiavaroli C, Hannaert P. Therapeutic Efficacy and Mechanism of Action of Ethamsylate, a Long-Standing Hemostatic Agent. Am J Ther. 2006;13(3):236-47. [Accessed 10 Apr. 2019] (online) Available from:
- Negrete R, Molina M, Gutierrez-Aceves J. Preoperative administration of ethamsylate: reduces blood loss associated with percutaneous nepholithotomy? A prospective randomized study. J Urol. 2009;181(4S):625. [Accessed 10 Apr. 2019] (online) Available from:
- Tranexamic Acid and Ethamsylate. Panchkula, Haryana: Biofield Pharma Pvt Ltd.; [Accessed 03 Apr. 2025] (online) Available from:
- Tranexamic Acid and Ethamsylate. Zeelab Pharmacy Pvt Ltd.; [Accessed 03 Apr. 2025] (online) Available from:
- Tranexamic Acid and Ethamsylate. Chandigarh, Punjab: Gracia Life Sciences; [Accessed 03 Apr. 2025] (online) Available from:
Marketer details
Name: Candor Biotech Ltd
Address: Candor Biotech Limited, SCO- 66, Sector 32- C, Chandigarh-160047, India
Country of origin: India
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₹71.7
Inclusive of all taxes
MRP₹79.69 10% OFF
15.0 tablets in 1 strip
SOLD OUT
Available alternative with same salt composition
Sylate T 500mg/250mg Tablet
strip of 10 tablets
by Emcure Pharmaceuticals Ltd
Get by 12am, Tomorrow
₹464
10% off
Tranexamic Acid (500mg) + Ethamsylate (250mg)