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Closalic MF Cream

Written By Dr. Subita Alagh, BDS
Reviewed By Dr. Lalit Kanodia, MBA, MD Pharmacology
Last updated on 03 Dec 2025 | 11:26 AM (IST)
Closalic MF Cream has a combination of medicines that are used to treat eczema and psoriasis. It helps to provide relief from redness, itching, and swelling. It removes dead skin cells and helps in softening the skin.
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₹85.7 MRP ₹93.759% off 
 
 
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General Information

Contains

Clobetasol (0.05% w/w)+ Salicylic Acid (3% w/w)

Marketer

Ektek Pharma

Storage

Store below 30°C
The content is shown in English
Closalic MF Cream image
Closalic MF Cream image

Product introduction

Closalic MF Cream should be used in the dose and duration as advised by your doctor. Wash your hands before using this medicine. It is advised to check the label for directions before use. It is for external use only.

Do not use this medicine more than the recommended dose. Inform your doctor if you have known allergies to this medicine. The common side effects of this medicine include peeling of the skin, thinning of the skin, burning, itching, irritation, and redness at the application site.

If these side effects or any other symptoms which you think are because of this medicine persist for a longer duration, please consult your doctor. Inform your doctor if you are pregnant or are suffering from any other disease. This medicine is safe to use in breastfeeding mothers.

Uses of Closalic MF Cream

Benefits of Closalic MF Cream

Treatment of Psoriasis
Psoriasis is a condition where the skin cells in the body grow too quickly and form scales and dry patches. They can grow anywhere, but most appear on the scalp, elbows, knees, and lower back. Closalic MF Cream reduces the scaly, itchy patches which may develop on the different parts of the body. Use it exactly as prescribed and for as long as it is prescribed to get the most benefit. It may take several months to become fully effective. You should avoid drinking alcohol while having this treatment and drink plenty of water to stay hydrated.
Treatment of Eczema
Eczema is a skin condition where patches of skin become inflamed, itchy, red, cracked, and rough. Closalic MF Cream helps in treating inflammation and itching in eczema. When used correctly it is a safe and effective treatment. Closalic MF Cream reduces the redness, rash, pain or itchiness caused by your skin’s reaction to an irritant. This improves your self-esteem and confidence as your appearance changes. You should always use the cream or ointment as prescribed and only apply the amount you have been told to. Keep using it for as long as it is prescribed to get the full benefits.

Side effects of Closalic MF Cream

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Closalic MF
  • Skin peeling
  • Thinning of skin
  • Application site reactions (burning, irritation, itching and redness)

How to use Closalic MF Cream

This medicine is for external use only. Use it in the dose and duration as advised by your doctor. Check the label for directions before use. Clean and dry the affected area and apply the cream. Wash your hands after applying, unless hands are the affected area.

How Closalic MF Cream works

Closalic MF Cream is a combination of two medicines: Clobetasol and Salicylic Acid, which treats eczema and psoriasis. Clobetasol is a steroid which blocks the production of certain chemical messengers (prostaglandins) that make the skin red, swollen and itchy. Salicylic Acid is a keratolytic medicine which breaks down keratin clumps, removes dead skin cells and softens the skin. It also enhances the absorption of Clobetasol into the skin.

Quick tips

  • Closalic MF Cream is used to treat the redness, swelling, itching, and discomfort of various skin conditions like eczema and psoriasis.
  • Apply to the affected areas as a thin film two or three times daily, or as advised by your doctor.
  • Don't cover the area being treated with airtight dressings such as bandages unless directed by a doctor, as this may increase the risk of side effects.
  • After you have applied Closalic MF Cream, remember to wash your hands (unless your hands are the treated area).
  • Use a mild moisturizer regularly to overcome the skin dryness during the course of treatment.
  • Consult your doctor if your skin condition has not improved after 2 weeks of treatment.

Safety advice

Alcohol

Alcohol

No interaction found/established
Pregnancy

Pregnancy

CONSULT YOUR DOCTOR
The safety of Closalic MF Cream during pregnancy has not been established. There are no adequate and well-controlled studies in pregnant women, and animal data on reproductive toxicity are insufficient. Your doctor will weigh the benefits and any potential risks before prescribing.
Breast feeding

Breast feeding

SAFE IF PRESCRIBED
Closalic MF Cream may be safe to use during breastfeeding. Animal studies have shown low or no adverse effects to the developing baby; however, there are limited human studies.
Driving

Driving

No interaction found/established
Kidney

Kidney

No interaction found/established
Liver

Liver

No interaction found/established

Frequently asked questions

Follow the directions given by the doctor or provided on the medicine. Apply the medicine thinly and in sufficient quantity to cover the affected areas. Closalic MF Cream is usually applied two or three times a day to the affected areas of skin. Wash your hands after using Closalic MF Cream, unless it is used for treating skin infection on the hands.
No, do not stop using Closalic MF Cream and complete the full course of treatment, even if you feel better. Your symptoms may improve before the disease is completely treated.
Closalic MF Cream should not be used on the face. Do not use the medication for longer than the advised periods of time. Do not apply a bandage or dressing to the area being treated, as this will increase absorption of the preparation and increase the risk of side effects. This medicine should only be used by the patient and never give it to other people, even if their condition appears to be the same.
No, Closalic MF Cream will not be more effective if overused. Overusing the medicine can result in too much medicine being absorbed into the body. This may lead to thinning or weakening of the skin and other serious side effects. If you are experiencing increased severity of your symptoms, please consult your doctor for re-evaluation.
Keep this medicine in the container or the pack it came in, tightly closed. Store it according to the instructions mentioned on the pack or label. Dispose of the unused medicine. Make sure it is not consumed by pets, children and other people.

Fact Box

Habit Forming

No

Therapeutic Class

DERMA

References

  1. Clobetasol propionate. Uxbridge, Middlesex: GlaxoSmithKline UK; 1993 [revised 18 Oct. 2017]. [Accessed 04 Apr. 2019] (online) Available from:
  2. Salicylic Acid. Huddersfield: Thornton & Ross Ltd.; 1985 [revised 20 Feb 2018]. [Accessed 03 Apr. 2019] (online) Available from:
  3. Clobetasol propionate. Melville, New York: Fougera Pharmaceuticals Inc.; 1994. [revised Nov. 2012] [Accessed 04 Apr. 2019] (online) Available from:
  4. PubChem. Salicylic acid. [Accessed 26 Apr. 2019] (online) Available from:
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Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Ektek Pharma
Address: 15l, model town, ludhiana, punjab, india - 141002

Vendor Details

Country of origin: India

Lab tests offered by us

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