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Clofros 100 Capsule

Clofazimine (100mg)
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Clofros 100 Capsule belongs to a class of drugs known as antileprotic medicines. It is used in combination with other medicines for the treatment of leprosy. It works by stopping the growth of disease-causing organisms in the body.

Written By Dr. Lipika Khurana, PGDHHM, BDS,
Reviewed By Dr. Sachin Gupta, MD Pharmacology, MBBS,
Last updated on 29 Apr 2026 | 01:01 PM (IST)
₹36.7 MRP ₹40.5610% off 
 
 
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Clofros 100 Capsule
Clofros 100 Capsule
strip of 10 capsules
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₹40.56
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Same composition
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Hansepran 100 Capsule
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General Information

The content is shown in English
Clofros 100 Capsule image
Clofros 100 Capsule image
Clofros 100 Capsule image

Product introduction

Clofros 100 Capsule should be used in the dose and duration as advised by your doctor. It should be taken with food, preferably at a fixed time. Avoid skipping any doses and finish the full course of treatment even if you feel better. Do not take a double dose to make up for a missed dose. Simply take the next dose as planned.

Some people may experience nausea, stomach upset, and vomiting as the side effects of this medicine. It may also discolor your skin, urine, saliva, tears, and other body fluids. This is normally temporary and resolves once the treatment is completed. Please consult your doctor if these side effects bother you or persist for a longer duration.

Uses of Clofros Capsule

  • Leprosy

Benefits of Clofros Capsule

Leprosy
Clofros 100 Capsule is used in the treatment of leprosy to help reduce skin lesions, nerve damage, and inflammation. It supports better disease control and is often used as part of a multi-drug therapy for effective management.

Side effects of Clofros Capsule

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Clofros
  • Eye discoloration
  • Abdominal pain
  • Vomiting
  • Nausea
  • Diarrhea
  • Loss of appetite
  • Rash
  • Itching
  • Skin peeling
  • Skin discoloration

How to use Clofros Capsule

Take this medicine in the dose and duration as advised by your doctor. Clofros 100 Capsule should be taken with or after food.

How Clofros Capsule works

Clofros 100 Capsule works by killing the bacteria that cause leprosy and preventing them from growing further. It also helps reduce the inflammation and skin problems that can occur with the disease.

All substitutes for Clofros 100 Capsule

For information purposes only. Consult a doctor before taking any medicine.

Quick tips

  • Clofros 100 Capsule is used in combination with other medicines for the treatment of leprosy.
  • Finish the prescribed course, even if you start to feel better. Stopping it early may make the infection come back and harder to treat.
  • Take it with or just after meal.
  • Take it as per the dose and duration prescribed by your doctor.
  • It may discolour your skin, urine, saliva, tears and other body fluids. This is normal and not harmful.

Safety advice

Alcohol

Alcohol

CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with Clofros 100 Capsule. Please consult your doctor.
Pregnancy

Pregnancy

CONSULT YOUR DOCTOR
Clofros 100 Capsule is not recommended during pregnancy as there is positive evidence of fetal risk based on animal studies. However, it may still be prescribed by a doctor in situations where the benefits outweigh the risks.
Breast feeding

Breast feeding

CAUTION
Clofros 100 Capsule should be used with caution during breastfeeding. Breastfeeding should be held until the treatment of the mother is completed and the drug is eliminated from the body.
Driving

Driving

UNSAFE
Clofros 100 Capsule may decrease alertness, affect your vision, or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
Kidney

Kidney

SAFE IF PRESCRIBED
Clofros 100 Capsule is probably safe to use in patients with kidney disease. Limited data suggest dose adjustment may not be needed.
Liver

Liver

CAUTION
Clofros 100 Capsule should be used with caution in patients with liver disease. Dose adjustment may be needed.

Interaction with drugs

Taking Clofros with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
Life-threatening

Domperidone (Oral Route)

Do not consume Clofazimine with Domperidone.
Life-threatening

Domperidone (Oral Route)

Do not consume Clofazimine with Domperidone.
Life-threatening

Domperidone (Oral Route)

Do not consume Clofazimine with Domperidone.
Life-threatening

Domperidone (Oral Route)

Do not consume Clofazimine with Domperidone.
Life-threatening

Domperidone (Oral Route)

Do not consume Clofazimine with Domperidone.

Frequently asked questions

Yes, Clofros 100 Capsule may cause orange-pink to brownish-black discoloration of the skin within a few weeks after you start using it. This skin discoloration may take several months or years to resolve even after completion of your treatment with Clofros 100 Capsule. Such conditions may cause the patient to become depressed or the patient may develop suicidal thoughts. You must discuss with your doctor if you feel depressed or have any suicidal thoughts, during or after your treatment. This medicine may also cause your sweat, tears, saliva, urine, stools, and the whites of your eyes to turn red or brownish-black in color. Consult your doctor if you experience any such changes or if you have any other concerns regarding this.
Use of Clofros 100 Capsule should be avoided in patients who are allergic to Clofros 100 Capsule or any of its components. However, if you are not aware of any allergy or if you are using Clofros 100 Capsule for the first time, consult your doctor.
Clofros 100 Capsule is safe if used in the dose and duration advised by your doctor. Take it exactly as directed and do not skip any dose. Follow your doctor's instructions carefully and let your doctor know if any of the side effects bother you.
If you forget a dose of Clofros 100 Capsule, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and take the next scheduled dose in the prescribed time. Do not double the dose to make up for the missed one as this may increase the chances of developing side effects.
No, do not stop taking Clofros 100 Capsule without consulting your doctor even if you feel better. Your symptoms may improve before the infection is completely cured. If you stop using Clofros 100 Capsule too early, the symptoms may return or worsen. Therefore, it is advised to continue taking Clofros 100 Capsule in the dose and duration advised by the doctor.

Fact Box

Chemical Class

Phenazine derivative

Habit Forming

No

Therapeutic Class

ANTI INFECTIVES

Action Class

Antileprotic Agents

References

  1. Gumbo T. Chemotherapy of Tuberculosis, Mycobacterium Avium Complex Disease, and Leprosy. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. p. 1560.
  2. Chambers HF, Deck DH. Antimycobacterial Drugs. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. p. 831.
  3. Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 295-96.
  4. ScienceDirect. Clofazimine. [Accessed 01 Apr. 2019] (online) Available from:
  5. Clofazimine. East Hanover, New Jersey: Novartis Pharmaceuticals; 1998 [revised Jul. 2002]. [Accessed 01 Apr. 2019] (online) Available from:
  6. Chaves RG, Lamounier JA. Breastfeeding and maternal medications. J Pediatr (Rio J). 2004;80(5 Suppl):S189-98. [Accessed 01 Apr. 2019] (online) Available from:
  7. Clofazimine [Prescribing Information]. East Hanover, NJ: Novartis Pharmaceuticals Corporation; 2019. [Accessed 25 Jul. 2024] (online) Available from:
  8. Clofazimine [Prescribing Information]. Mumbai, Maharashtra: Macleods Pharmaceuticals Ltd.; [Accessed 04 Nov. 2025] (online)
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User feedback

Leprosy
83%
Others
17%
Average
33%
Excellent
33%
Poor
33%
Loss of appetite
33%
No Side Effect
33%
Nausea
33%
With food
67%
Empty stomach
33%
Expensive
56%
Not Expensive
33%
Average
11%
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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Sangrose Laboratories Pvt Ltd
Address: SANGROSE LABORATORIES PVT LTD , INDUSTRIAL ESTATE KALLIMEL P.O, MAVELIKARA-690 509, KERALA.

Vendor Details

Country of origin: India
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