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Clofazimine is used in the treatment of leprosy.

How it works

Clofazimine belongs to a class of drugs called leprostatics. It works by acting on the DNA of bacteria that causes leprosy.

Common side effects

Vomiting, Nausea, Diarrhoea, Loss of appetite, Rash, Itching, Scaling of skin, Skin discolouration, Eye discolouration


Expert advice

  • Keep taking clofazimine for the full course of treatment, even if you begin to feel better after a few months.
  • Do not get exposed to sunlight even for a brief period of time as clofazimine may cause your skin to become more sensitive to sunlight.
  • Use of clofazimine may cause pink or red to brownish-black discoloration of the skin within few weeks.
  • Take precautions while taking clofazimine as it may cause some stomach upset, but on rare occasion it may also cause severe, sharp abdominal pain and burning.
  • Do not drive or operate machinery as clofazimine may cause dizziness and drowsiness.

Content on this page was last updated on 11 November, 2016, by Dr. Varun Gupta (MD Pharmacology)